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Drug for treating coronary heart disease and preparation method thereof

A production method and technology for coronary heart disease, applied in the field of medicine, can solve the problems of slow curative effect, large side effects, single pharmacological action, etc., and achieve the effects of short treatment period and significant curative effect.

Inactive Publication Date: 2018-05-11
GUIZHOU RUNSHENG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, there are many medicines for the clinical treatment of coronary heart disease. Among them, the western medicine for the treatment of coronary heart disease has relatively large side effects and single pharmacological effect, while the traditional Chinese medicine currently used for the treatment of coronary heart disease has unsatisfactory effects and slow curative effect.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Recipe: 15 parts of Ziheche, 8 parts of antlers, 13 parts of Wulingzhi, 20 parts of heterophylla, 15 parts of Fritillaria, 8 parts of Salvia, 10 parts of Chuanxiong, 15 parts of Pinellia, 13 parts of sandalwood, 13 parts of cassia 11 parts of Chuanxiong, 12 parts of Wulingzhi, 16 parts of Polygonum cuspidatum, 13 parts of Yujin

[0015] Process: Add 10 times the amount of water to decoct 3 times, each time for 1.5h, filter, combine the decoction liquid, and concentrate it into an extract with a relative density of 1.15-1.20 at 50-60°C, and the amount of extract and extract is 20% Starch and 20% dextrin powder are mixed and granulated, and dried to obtain granules.

[0016] Specifications: 5g / bag.

[0017] Usage and dosage: 5-10g each time, 2-3 times a day.

Embodiment 2

[0019] Recipe: 15 parts of Ziheche, 8 parts of antlers, 13 parts of Wulingzhi, 20 parts of heterophylla, 15 parts of Fritillaria, 8 parts of Salvia, 10 parts of Chuanxiong, 15 parts of Pinellia, 13 parts of sandalwood, 13 parts of cassia 11 parts of Chuanxiong, 12 parts of Wulingzhi, 16 parts of Polygonum cuspidatum, 13 parts of Yujin

[0020] Process: Take the above-mentioned drug, reflux extract with 6 times the amount of 70% ethanol twice, each time for 1 hour, filter the extract, recover the ethanol from the filtrate and concentrate it into an extract with a relative density of 1.20-1.25 at 50-60°C, and another Take 30% starch and 0.7% magnesium stearate in the extract, mix them with the extract, granulate with 60% ethanol, dry, crush, and fill capsules to obtain capsules.

[0021] Specification: 0.3g / grain.

[0022] Usage and dosage: 5-10g each time, 2-3 times a day.

Embodiment 3

[0024] Recipe: 15 parts of Ziheche, 8 parts of antlers, 13 parts of Wulingzhi, 20 parts of heterophylla, 15 parts of Fritillaria, 8 parts of Salvia, 10 parts of Chuanxiong, 15 parts of Pinellia, 13 parts of sandalwood, 13 parts of Cassia 11 parts of Chuanxiong, 12 parts of Wulingzhi, 16 parts of Polygonum cuspidatum, 13 parts of Yujin

[0025] Process: Take the above medicine, add 10 times the amount of water to decoct 3 times, each time for 1.5h, filter, combine the decoction liquid, concentrate it into an extract with a relative density of 1.15-1.20 at 50-60°C, mix the extract with the above Mix powder and extract with 20% starch, compress into tablets, and coat with film to obtain tablets.

[0026] Specification: 0.3g / piece.

[0027] Usage and dosage: 5-10g each time, 2-3 times a day.

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PUM

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Abstract

The invention provides a drug for treating the coronary heart disease. The drug comprises, by weight, 10 to 20 parts of human placentae, 5 to 10 parts of antler, 10 to 16 parts of flying squirrel feces, 15 to 25 parts of pseudostellaria roots, 10 to 20 parts of Zhejiang fritillaria bulbs, 5 to 15 parts of red sage roots, 8 to 15 parts of Ligusticum wallichii, 10 to 20 parts of prepared pinellia tubers, 10 to 16 parts of santal, 10 to 15 parts of cassia seeds, 8 to 16 parts of Ligusticum wallichii, 8 to 15 parts of flying squirrel feces, 12 to 18 parts of gentrin knotweed and 10 to 16 parts ofcurcuma tubers. The preparation method is simple and easily practicable; and the drug is short in treatment course, free of toxic and side effect, substantial in curative effect, fast in action, freeof other high-priced adjuvant treatment and low in cost, causes no pain and no wound in usage and allows the cured coronary heart disease not to recur. The drug can be used for treating a variety of acute and chronic gastric ulcer and gastritis. The raw materials of the drug produce good synergism and coact to treat the coronary heart disease, and the drug has the advantages of substantial curative effect, short treatment period, safety and no side effect.

Description

technical field [0001] The invention relates to a medicine for treating coronary heart disease and a preparation method thereof, belonging to the field of medicine technology. Background technique [0002] Coronary atherosclerotic heart disease is a heart disease caused by atherosclerotic lesions in the coronary arteries that cause stenosis or blockage of the vessel lumen, resulting in myocardial ischemia, hypoxia or necrosis. It is often called "coronary heart disease". However, the scope of coronary heart disease may be wider, including inflammation, embolism, etc. leading to stenosis or occlusion of the lumen. The World Health Organization divides coronary heart disease into five categories: asymptomatic myocardial ischemia (occult coronary heart disease), angina pectoris, myocardial infarction, ischemic heart failure (ischemic heart disease) and sudden death. Clinically, it is often divided into stable coronary artery disease and acute coronary syndrome. [0003] There...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P9/10A61K35/24A61K35/32A61K35/50
CPCA61K35/50A61K9/1652A61K9/2059A61K9/4866A61K35/24A61K35/32A61K36/185A61K36/236A61K36/36A61K36/482A61K36/537A61K36/704A61K36/8888A61K36/8966A61K36/9066A61K2236/331A61K2236/333A61K2236/39A61K2300/00
Inventor 杨志勇陈修仕陈才献
Owner GUIZHOU RUNSHENG PHARMA