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Preparation method of dressing suitable for burns

A porous material and temperature control technology, applied in the medical and health field, can solve the problems of poor antibacterial and antibacterial ability, unfavorable wound healing, unsuitable hemostatic dressing for burn wounds, etc., to isolate external bacteria, promote burn or scald healing, and achieve good biological phase capacitive effect

Inactive Publication Date: 2018-06-15
SUZHOU ORIZA MEDICAL INSTR CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The technical problem to be solved by the present invention is that the hemostatic dressing prepared by the medical dressing preparation method in the prior art is not suitable for burn wounds, is not conducive to wound healing, and has poor antibacterial and antibacterial ability. Preparation method of dressing beneficial to wound healing and high antibacterial and antibacterial ability

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] The preparation method of the dressing that is applicable to the burn of the present embodiment, the steps are as follows:

[0021] (1) Take the polymer material, add it into water, stir until it is completely dissolved, and after mixing evenly, under vacuum conditions, control the temperature to 300°C, and perform heating and foaming treatment to obtain a porous material;

[0022] (2) Weigh 20g of collagen particles and grind them into powder, dissolve them in water to make a colloidal liquid with a mass fraction of 0.5% to 10%, add 5g of sodium alginate, stir well and pour it on a glass or stainless steel plate On the surface, casting into a film, drying at room temperature to obtain a film-like bioabsorbable film;

[0023] (3) The bioabsorbable membrane obtained in step (2) is crimped with the porous material after foaming treatment in step (1), and then placed in a vacuum to freeze-dry, and the temperature is controlled to - Freeze-drying at 80° C. for 2 hours to o...

Embodiment 2

[0025] The preparation method of the dressing that is applicable to the burn of the present embodiment, the steps are as follows:

[0026] (1) Take 20g of gelatin, add it to water, then add 0.02g of hydroxypropyl methylcellulose, stir until it is completely dissolved, mix evenly, and control the temperature at 100°C under vacuum conditions to perform heating and foaming treatment , molding for 2 hours, the porous material is obtained;

[0027] (2) Weigh 20g of gelatin particles and grind them into powder, dissolve them in water to make a colloidal liquid with a mass fraction of 0.5% to 10%, add 5g of sodium alginate, stir well and pour it on a glass or stainless steel plate , cast into a film, and dry at room temperature to obtain a film-like bioabsorbable film;

[0028] (3) The bioabsorbable membrane obtained in step (2) is crimped with the porous material after foaming treatment in step (1), and then placed in a vacuum to freeze-dry, and the temperature is controlled to - ...

Embodiment 3

[0030] The preparation method of the dressing that is applicable to the burn of the present embodiment, the steps are as follows:

[0031] (1) Take 20g of bone collagen, add it to water, then add 0.08g of hydroxypropyl methylcellulose, stir until completely dissolved, mix well, and control the temperature at 100°C under vacuum conditions to heat and foam Processing and molding for 2 hours, the porous material is obtained;

[0032] (2) Weigh 20g of gelatin particles and grind them into powder, dissolve them in water to make a colloidal liquid with a mass fraction of 0.5% to 10%, add 5g of sodium alginate, stir well and pour it on a glass or stainless steel plate , cast into a film, and dry at room temperature to obtain a film-like bioabsorbable film;

[0033] (3) The bioabsorbable membrane obtained in step (2) is crimped with the porous material after foaming treatment in step (1), and then placed in a vacuum to freeze-dry, and the temperature is controlled to - Freeze-dry at...

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PUM

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Abstract

The invention provides a preparation method of a dressing suitable for burns. The preparation method comprises the following steps: obtaining a porous material in a heating and foaming treatment manner for natural polymers; and compounding the porous material with a film-like bio-absorption membrane. The preparation method provided by the invention is simple to operate and solves a problem that the dressing is not suitable for burns or scalds in the prior art; the prepared hemostatic dressing has excellent biocompatibility, fits with a wound surface well, can isolate external bacteria, and better promotes healing of the burns or the scalds.

Description

technical field [0001] The invention relates to the medical and health field, in particular to a preparation method of a dressing suitable for burns. Background technique [0002] Scalds or burns are collectively referred to as "burns", which are common traumas that not only cause damage to the skin, but also can cause severe systemic reactions, especially for large-scale burns. The systemic reactions are very severe, such as fluid leakage, infection, Absorption of toxins, etc. may cause metabolic disorders and dysfunction of various systems and organs, and high mortality. At the same time, if the burn wound is not treated properly (such as red lotion, toothpaste, dog oil and some traditional Chinese medicine prescriptions, etc.), it is easy to cause wound infection, deepen the wound, and prolong the healing time of the burn, which will increase the pain of the patient and form scars or scar hyperplasia. , contractures and other sequelae such as deformity, dysfunction, and ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/32A61L15/42
CPCA61L15/32A61L15/325A61L15/425A61L2400/04C08L89/00
Inventor 吴鸿
Owner SUZHOU ORIZA MEDICAL INSTR CO LTD
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