A magnetic graphene oxide immobilized enzyme and its application in wet corn soaking
A technology for immobilizing enzymes and oxidized stones, applied to biochemical equipment and methods, enzymes, etc. fixed on or in inorganic carriers, can solve the problems of reducing economic benefits, environmental pollution, corrosion of equipment and pipelines, etc., and achieve protein The effect of low content, high yield and low dosage
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Embodiment 1
[0018] (1) Take 10g of graphene oxide (GO) and add 600mL of ethanol solution with a volume fraction of 30%, after 30KHz ultrasonic dispersion for 0.5h, add ferrous chloride (15mmol) and ferric chloride (30mmol) under stirring, and continue stirring After 30 minutes, react at 50°C for 2 hours, add ammonia water to adjust the pH to 11, and continue stirring for 1 hour, then magnetically separate, wash with water, and dry to obtain GO / Fe 3 o 4 Composite magnetic materials;
[0019] (2) Take the GO / Fe obtained in step (1) 3 o 4 Composite magnetic material (1.0g) and papain (50mg) were placed in 80mL phosphate buffer solution pH 6.0, and after 30KHz ultrasonication for 45min, the magnetic graphene oxide immobilized enzyme (hereinafter referred to as product) was obtained by magnetic separation, washing and drying. A, the enzyme immobilization rate is 82.1%).
Embodiment 2
[0021] (1) Take 10g of graphene oxide (GO) and add 400mL of ethanol solution with a volume fraction of 50%. After 40KHz ultrasonic dispersion for 0.5h, add ferrous sulfate (25mmol) and ferric sulfate (50mmol) under stirring, and continue stirring for 30 minutes Finally, react at reflux temperature for 1 hour, add ammonia water to adjust the pH to 11, continue to stir for 2 hours, and obtain GO / Fe by magnetic separation, washing and drying. 3 o 4 Composite magnetic materials;
[0022] (2) Take the GO / Fe obtained in step (1) 3 o 4 Composite magnetic material (1.0g) and papain (80mg) were placed in 100mL phosphate buffer solution pH 7.0, and after 40KHz ultrasonication for 30min, the magnetic graphene oxide immobilized enzyme (hereinafter referred to as product) was obtained by magnetic separation, washing and drying. B, the immobilization rate of the enzyme is 80.5%).
Embodiment 3
[0024] Commercially available degerminated corn (100kg) was crushed to 20-40 mesh, water (300kg) and product A (100g) were added, and after stirring and soaking at 50°C for 6 hours, the magnetic graphene oxide immobilized enzyme was reclaimed by magnetic separation ( After the recovery rate is 99.2%), the remaining soaked mixture is transferred to a pulverizer for fine pulverization, and the filtrate is allowed to stand overnight after crossing a 200 mesh sieve, centrifuged, and dried to obtain 71.3kg of cornstarch (protein≤0.4%).
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