Three-layer structural composite artificial blood vessel

Abstract

The invention discloses a three-layer structural composite artificial blood vessel, and belongs to the field of medical apparatuses. The three-layer structural composite artificial blood vessel is composed of a dense blood retaining layer, an elastomer layer and a fiber-reinforced layer, wherein the dense blood retaining layer is arranged on the inner surface of a vessel body; the elastomer layeris arranged in the middle of the vessel body; and the fiber-reinforced layer is arranged on the outer surface of the vessel body. Pores are distributed in the blood retaining layer, the elastomer layer and the fiber-reinforced layer; and the size of the pores follows a trend of being increased from inner layer to outer layer. Blood retaining performance, tissue growth-in performance, anti-thrombotic property, mechanical strength and thickness of various layers of the artificial blood vessel are in gradient change; the blood retaining performance has a trend of being increased from outer layerto inner layer; the cell growth-in performance has a trend of being decreased from outer layer to inner layer; the anti-thrombotic property has a trend of being increased from outer layer to inner layer; and the mechanical strength has a trend of being decreased from outer layer to inner layer. The three-layer structural composite artificial blood vessel provided by the invention is excellent in penetration resistance, anti-thrombotic property, compliance, bio-compatibility and mechanical performance.

Description

technical field

[0001] The invention belongs to the field of medical devices, and in particular relates to a three-layer composite artificial blood vessel with good permeability resistance, antithrombotic performance, compliance, biocompatibility and mechanical properties. Background technique

[0002] The vascular system includes the heart, blood vessels, and blood. The heart transports fresh blood to various parts of the body through large and small blood vessels to exchange nutrients and waste in the body to ensure the normal function of various organs. However, atherosclerosis, hemangioma, and external trauma cause a variety of arterial and venous vascular defects, and it is necessary to use vascular substitutes of different diameters through surgery to replace the corresponding diseased blood vessel, bypass and other repair treatments. Blood vessel substitutes generally include autologous blood vessels, xenograft blood vessels, allogeneic blood vessels, and artificial ...

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