MTHFR (methylenetetrahydrofolate reductase) gene fragment as SNP (single-nucleotide polymorphism) molecular marker associated with sow foot-leg bone density

A technology of molecular markers and bone density, which is applied in the determination/inspection of microorganisms, biochemical equipment and methods, etc., can solve the problems of high price, limited application, rare research on livestock bones, etc., and achieve high sensitivity and good specificity
CN108411005AActive Publication Date: 2018-08-17HUAZHONG AGRI UNIV
0 Cites 2 Cited by

Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
HUAZHONG AGRI UNIV
Publication Date
2018-08-17

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

The invention belongs to the technical field of animal molecular marking and particularly relates to MTHFR (methylenetetrahydrofolate reductase) gene fragment as an SNP (single-nucleotide polymorphism) molecular marker associated with sow foot-leg bone mineral density. The molecular marker is cloned from the MTHFR gene fragment having the register number of M1GA0008657; the gene fragment is subjected to typing screening via a gene chip technology so as to obtain the molecular marker associated with sow foot-leg bone mineral density; a nucleotide sequence of the molecular marker is shown as inSEQ ID NO: 1; base 51 of the nucleotide sequence has an A / C allele mutation; when nucleotide 51 in the SEQ ID NO: 1 is A, sow leg-foot bone has higher bone mineral density. Disclosed a method of screening molecular markers associated with sow pig-leg bone mineral density, as well as application of association analytical method. The novel SNP molecular marker is provided for marking-assisted selection of pig leg-foot compactness traits, particularly bone mineral density.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The invention relates to the technical field of preparation of pig molecular markers, in particular to the use of MTHFR gene fragments as SNP molecular markers related to bone density of sows' limbs and hooves. The molecular marker of the invention is cloned from the MTHFR gene, and can be used to predict the bone density traits of pig limbs and hooves. Background technique

[0002] With the development of science and technology, the pig breeding industry has made significant breakthroughs in genetic breeding, nutritional regulation, and disease prevention and control. The lean meat rate, feed-to-meat ratio, and growth rate of commercial pigs have all been greatly improved. However, with intensive farming comes the increasingly prominent problem of limbs and feet. For intensive production, the range of activities of pigs is limited. In addition, the design of pens (slatted floors) has exacerbated the occurrence of pigs' limbs and feet. It has been rep...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More