Bioactive pancreas islet glucose regulating preparation and preparation method thereof

Abstract

The invention provides a bioactive pancreas islet glucose regulating preparation and a preparation method thereof. The preparation is prepared from main materials including pancreas protein polypeptides and pancreas islet active cells of animals (such as pigs, cattle and sheep) and medicinal auxiliary materials. The preparation method includes: preparing high-activity pancreas islet cell coating liquid and trypsin polypeptide liquid from healthy animal pancreases through a series of integrated processes including separation, purification, multiplication culture, coating, ultrafiltration and the like; proportionally mixing, and adding a stabilizing agent and an absorbent; preparing into lyophilized powder through lyophilization, or preparing into enteric capsules. Pancreas islet active cells and trypsin polypeptides are directly replenished to bodies by biological means, the large quantity of pancreas islet active cells and trypsin polypeptides cultured in vitro are absorbed to give full play to a biological group effect in vivo, and accordingly the normal glucose metabolic level can be maintained, and diabetic complications can be effectively controlled.

Description

technical field [0001] The invention belongs to the technical field of biological preparation, and in particular relates to a preparation of biologically active pancreatine tongtangbao and a preparation method thereof. Background technique [0002] Diabetes is an absolute or relative lack of insulin in the blood, leading to high blood sugar and diabetes, which in turn causes fat and protein metabolism disorders. Clinically, polyuria, polydipsia, polydipsia, polyphagia, weight loss and other manifestations may occur. Diabetes exists for a long time Hyperglycemia in the blood can lead to chronic damage and dysfunction of various tissues, especially the eyes, kidneys, heart, blood vessels, and nerves. Due to economic development, changes in people's diet structure, and population aging, the number of diabetic patients has increased rapidly. Diabetes has become a global disease that endangers human health, with an incidence rate of 3-5%. The mortality rate is second only to card...

AI Technical Summary

Problems solved by technology

The present invention finds another way to directly supplement the body with active islet cells and trypsin polypeptides through biological means, so that after a large number of active islet cells cultured in vitro are absorbed by the body, they can fully exert their biological effects in the body, release insulin, protect the nutritional level of islets, and regulate Glucose metabolism, effective control of blood sugar ecological balance and diabetic complications, there is no use, sales and reports of islet active cell sugar-regulating oral preparations