Inulin composite tablet and preparation method thereof, and rotary tablet pressing machine
A technology for composite tablets and tablet presses, which is applied in the directions of presses, material forming presses, manufacturing tools, etc., can solve the problems of increasing the difficulty of preparation, reducing the content of inulin, and reducing the efficacy of products, etc.
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[0079] The embodiment of the present invention also provides a preparation method of the inulin composite sheet described in any one of the above embodiments, comprising:
[0080] Weighing the following components by weight percentage respectively: 50-95% of inulin and 5-50% of zeolite;
[0081] The weighed components are mixed, and the mixed components are compressed with a rotary tablet machine to obtain the inulin composite tablet.
[0082] At present, the preparation method of tablet is mainly the wet granulation tableting method, that is, firstly add a binder to the drug powder, rely on the bridging or bonding effect of the binder to make the drug powder agglomerate together to form granules, and then granulate the granules A method of drying and then compressing into tablets. In the actual production process, the process of preparing granules needs to be reacted in a high-temperature tower, and inulin is prone to hydrolysis reaction at high temperature, and it is also e...
Embodiment 1
[0095] Pass the inulin raw material through a 100-mesh sieve, and pass the zeolite raw material through a 500-mesh sieve to remove large particles, then weigh 500 g of inulin and 500 g of zeolite after passing through the sieve, and mix the weighed inulin and zeolite. A mixed powder was formed. Through the programmable logic controller (Programmable Logic Controller, PLC) that is set on the rotary tablet press, the tablet pressing temperature is set to be 20°C, and the linear speed of the mold axis rotating with the turntable is 50m / min, and then passed through the rotary tablet press Put the powder feeding device into the main body of the tablet press to compress the mixed powder to obtain inulin composite tablets.
Embodiment 2
[0097] Pass the inulin raw material through a 150-mesh sieve, pass the zeolite raw material through a 500-mesh sieve, weigh 950 g of inulin and 50 g of zeolite after passing the sieve, and mix the weighed inulin and zeolite to form a mixed powder. The tablet pressing temperature is set to 18°C by the PLC installed on the rotary tablet press, and the linear speed of the mold axis rotating with the turntable is 70m / min, and then the powder feeding device of the rotary tablet press is put into the tablet press body, with The mixed powder is compressed into tablets to obtain inulin composite tablets.
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