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Preparation method of anterior chamber separation saccule

A technology of isolating balls and balloons, applied in ophthalmic surgery, etc., can solve the problems of low corneal endothelial density, corneal endothelial cell damage, corneal damage, etc., to reduce the risk of corneal damage, facilitate surgical operations, and have good durability

Active Publication Date: 2018-10-02
广州锐澄医疗技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Phacoemulsification of the crystal nucleus will cause varying degrees of damage to the corneal endothelial cells, resulting in a low cure rate of cataract and greater pain to the patient
In the past, doctors used air or balanced salt solution to maintain the anterior chamber surgical space, but their protective effect on the corneal endothelium was weak
[0003] At present, before performing phacoemulsification cataract extraction, it is necessary to know the condition of the patient's corneal endothelial cells. If the corneal endothelial density is low, the operation cannot be performed, so that the patient cannot receive timely and effective treatment
Later, viscoelastic agent became an ideal adjuvant in phacoemulsification. Although viscoelastic agent is an ideal adjuvant in phacoemulsification cataract extraction, it also brings many adverse reactions to the patient's cornea and its adjacent tissues.
For example, due to unclean cleaning, its own composition and molecular structure, etc. during use, the corneal endothelium will be insufficiently protected and the cornea will be damaged.

Method used

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  • Preparation method of anterior chamber separation saccule

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] A kind of embodiment of the preparation method of anterior chamber isolation balloon of the present invention comprises the following steps:

[0029] (1) Take polyethylene (PE) for dust removal to remove mixed dust or foreign matter; then place it in a blast drying oven and dry it at 50°C for 24 hours to remove the contained moisture. The moisture content of the dried particles is 0.5% ;

[0030] (2) Put the dried polymer material into the extruder to form a pipe. Extrusion parameters: feed port temperature 79°C, extruder temperature 350°C, screw speed 10RPM, melt pump speed 90RPM, traction speed 10m / min , the water cooling solidification temperature is 10°C;

[0031] (3) The extruded pipe is stretched into a thin-walled pipe in a stretching machine. The stretching parameters: heating to 80°C, 200mm / s stretching speed along the axial direction, stretching distance of 100mm at the left and right ends, heating time 10s;

[0032] (4) The stretched thin-walled pipe is pl...

Embodiment 2

[0035] A kind of embodiment of the preparation method of anterior chamber isolation balloon of the present invention comprises the following steps:

[0036] (1) Take nylon (PA) for dust removal to remove mixed dust or foreign matter; then place it in a blast drying oven and dry it at 55°C for 20 hours to remove the contained moisture. The moisture content of the dried particles is 0.73%;

[0037] (2) Put the dried polymer material into the extruder to form a pipe. Extrusion parameters: feed port temperature 70°C, extruder temperature 300°C, screw speed 20RPM, melt pump speed 80RPM, traction speed 15m / min , the water cooling solidification temperature is 15°C;

[0038] (3) The extruded pipe is stretched into a thin-walled pipe in a stretching machine. The stretching parameters are: heated to 130°C, the stretching speed is 180mm / s along the axial direction, the stretching distance at the left and right ends is 135mm, and the heating time 12s;

[0039] (4) The stretched thin-wa...

Embodiment 3

[0042] A kind of embodiment of the preparation method of anterior chamber isolation balloon of the present invention comprises the following steps:

[0043] (1) Take polyurethane (PU) for dust removal to remove mixed dust or foreign matter; then place it in a blast drying oven and dry it at 60°C for 18 hours to remove the contained moisture, and the moisture content of the dried particles is 1%;

[0044] (2) Put the dried polymer material into the extruder to form a pipe. Extrusion parameters: feed port temperature 60°C, extruder temperature 250°C, screw speed 45RPM, melt pump speed 50RPM, traction speed 40m / min , the water cooling solidification temperature is 25°C;

[0045] (3) The extruded pipe is stretched into a thin-walled pipe in a stretching machine. The stretching parameters are: heated to 180°C, the stretching speed is 150mm / s along the axial direction, the stretching distance at the left and right ends is 160mm, and the heating time 15s;

[0046] (4) The stretched...

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PUM

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Abstract

The invention discloses a preparation method of an anterior chamber separation saccule. The preparation method includes the steps: taking a half-compliance and / or non-compliance high-molecular material to remove dust, and placing the material into an air dry oven to perform drying; (2) placing the dried material into an extruding machine to form a pipe; (3) stretching the extruded pipe in a stretcher to form a thin-wall pipe; (4) placing the stretched thin-wall pipe into a saccule mold to perform blow molding, blowing-up a parison to cling on the inner wall of the mold, performing cooling anddemolding to obtain the saccule, and arranging a catheter on the saccule; (5) folding the saccule prepared in the step (4) by taking the catheter as a axis through a saccule folding machine to obtainthe anterior chamber separation saccule. The saccule prepared by the method is high in strength, good in durability and of an oblate spheroid structure, the diameter of the saccule is 8-9mm, the plumped height of the saccule is about 1mm, sufficient space can be reserved for an operation when phacoemulsification cataract extraction is performed, and corneal endothelial cells can be effectively protected.

Description

technical field [0001] The invention relates to the technical field of medical operation assistance, in particular to a preparation method of an anterior chamber isolation balloon. Background technique [0002] The most widely used cataract surgery method in my country is phacoemulsification cataract extraction. The corneal endothelial cells will be damaged to varying degrees during phacoemulsification of the crystal nucleus, which will lead to a low cure rate of cataract and bring greater pain to the patient. In the past, doctors used air or balanced saline solution to maintain the anterior chamber surgical space, but their protective effect on the corneal endothelium was weak. [0003] At present, before performing phacoemulsification cataract extraction, it is necessary to know the condition of the patient's corneal endothelial cells. If the density of the corneal endothelium is low, the operation cannot be performed, so that the patient cannot receive timely and effecti...

Claims

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Application Information

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IPC IPC(8): A61F9/007
CPCA61F9/007
Inventor 王晓然曾晨光李少军郑亚新李锐聪郭少成杨习锋
Owner 广州锐澄医疗技术有限公司
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