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A Method for Simultaneously Detecting 12 Kinds of Alkaline Drugs in Hair

A hair and alkaline technology, applied in the field of simultaneous detection of 12 kinds of alkaline drugs in hair, can solve problems such as missed detection, achieve a wide range of analysis, considerable market potential, and facilitate data accumulation

Active Publication Date: 2021-04-09
ACADEMY OF FORENSIC SCIENCE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In this case, if only the method for a single drug is used for analysis, it is easy to cause missed detection. Therefore, in practice, there is an urgent need for a screening analysis method for multiple types of drugs and their metabolites in hair.

Method used

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  • A Method for Simultaneously Detecting 12 Kinds of Alkaline Drugs in Hair
  • A Method for Simultaneously Detecting 12 Kinds of Alkaline Drugs in Hair
  • A Method for Simultaneously Detecting 12 Kinds of Alkaline Drugs in Hair

Examples

Experimental program
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Effect test

Embodiment 1

[0079] A police station sent his hair for inspection, and the suspect claimed that he had never touched drugs. The hair sent for inspection is analyzed by the method of the present invention, not only methamphetamine and its metabolite amphetamine are detected in its scalp 0-3cm section, but also MDMA and its metabolite MDA are detected simultaneously, and the specific detection results are shown in figure 1 .

Embodiment 2

[0081] A police station submitted hair for inspection, and the suspect admitted to skating "ice"; the hair submitted for inspection was analyzed by the method described in the present invention, not only methamphetamine and its metabolite amphetamine were detected, but also ketamine and its metabolite to Methylketamine; It can be seen that the application of the method of the present invention can simultaneously screen multiple alkaline drugs to reduce the risk of missed detection. For the detection results of this embodiment, see figure 2 .

Embodiment 3

[0083] A police station submitted hair for inspection, and the suspect admitted to skating "ice"; the hair submitted for inspection was analyzed by the method described in the present invention, not only MDMA and its metabolite MDA, but also ketamine and its metabolite norketamine were detected. Cocaine and its metabolite benzoylecgonine; it can be seen that the method of the present invention can be used to screen a variety of alkaline drugs at the same time to reduce the risk of missed detection. For the detection results of this embodiment, see image 3 .

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Abstract

The invention belongs to the technical field of drug detection, in particular to a method for simultaneously detecting 12 kinds of alkaline drugs in hair. The method for simultaneously analyzing 12 kinds of psychoactive drugs in hair is simple, rapid and has a wide analysis range. Compared with the existing methods, the present invention saves the liquid-liquid extraction process in the sample pretreatment, and the whole process can be completed within 1 hour without increasing the time; on the contrary, when multiple samples are analyzed, it shows high-throughput Advantage. The technical solution provided by the invention can realize external pollution detection and real-time quantitative analysis of actual cases, and is convenient for data accumulation of positive cases. Therefore, the method for simultaneously detecting 12 kinds of basic drugs in hair of the present invention has excellent selectivity, linear correlation, precision and accuracy, and at the same time, the LOD and LOQ are low enough, so that it can successfully be used for inferring the source of drugs and correctly distinguishing them. It provides technical support for illegal abuse and clinical drug use, and has considerable market potential.

Description

technical field [0001] The invention belongs to the technical field of drug detection, in particular to a method for simultaneously detecting 12 basic drugs in hair. Background technique [0002] As we all know, basic drugs represented by morphine, codeine, methamphetamine, and amphetamine are the most widespread and most harmful in my country. [0003] Compared with other biological samples such as blood and urine, hair samples have the advantages of easy acquisition, easy storage, stable target objects, and a long detection time limit. In particular, hair samples can reflect for a long time (months or years) ), therefore, it plays an important role in the identification of forensic drug ingestion, and has become the evidence of drug addiction identification in our country. [0004] In addition, in judicial identification, the detection of drug components in human hair samples has been added as scientific evidence for identifying drug addicts; however, there is still a lac...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N30/06G01N30/88
CPCG01N30/06G01N30/88
Inventor 向平乔正卓悦陈航施妍沈敏
Owner ACADEMY OF FORENSIC SCIENCE
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