Expandable hemostatic sponge for nasal cavity filling and preparation method thereof
A hemostatic sponge and nasal cavity technology, applied in the field of medical materials, can solve the problems of lack of hemostasis, anti-inflammatory and antibacterial effects, non-degradable packing hemostatic materials, dysfunctional secretion, etc., and achieve good biodegradability, good biocompatibility, enhanced The effect of exudate absorption
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
example 1
[0025] Take 2g of chitosan and add it to 80g of absolute ethanol, stir at 300r / min for 20min, and add 1.2g of succinic anhydride, after mixing evenly, keep it in a constant temperature water bath at 40°C for 1h, cool to room temperature and filter to obtain a filter residue. The fraction is 75% ethanol solution to wash the filter residue 3 times, put it in a drying oven, and dry it to constant weight at 70°C to obtain N-succinoyl chitosan. Take 5g of sodium alginate, add it to 200mL of deionized water, and heat it at 300r / min and stirred for 10min, then added 5g of sodium periodate solution with a mass fraction of 5%, and placed in a dark place for oxidation reaction for 20h, after the reaction was completed, 1.0g of ethylene glycol was added, stirred for 10min, and the reaction solution was obtained. Take 10g of chlorine Sodium chloride and 200g of absolute ethanol were added to the reaction solution, stirred at 300r / min for 20min, left to stand and precipitated until no prec...
example 2
[0027]Take 3g of chitosan and add it to 90g of absolute ethanol, stir at 350r / min for 25min, and add 1.4g of succinic anhydride, after mixing evenly, keep it in a constant temperature water bath at 43°C for 1h, cool to room temperature and filter to obtain a filter residue. The fraction is 75% ethanol solution to wash the filter residue 4 times, put it in a drying oven, and dry it at 75°C until it reaches a constant weight to obtain N-succinoyl chitosan. Take 7g of sodium alginate, add it to 250mL of deionized water, and heat it at 350r / min and stirred for 13min, then added 6.5g mass fraction of 5% sodium periodate solution, and placed in a dark place for oxidation reaction for 22h, after the reaction was completed, 1.3g ethylene glycol was added, stirred for 13min, to obtain the reaction solution, take 11g Sodium chloride and 250g of absolute ethanol were added to the reaction liquid, stirred at 350r / min for 25min, left to precipitate until no precipitation occurred, and then...
example 3
[0029] Take 4g of chitosan and add it to 100g of absolute ethanol, stir at 400r / min for 30min, and add 1.5g of succinic anhydride, after mixing evenly, keep it in a constant temperature water bath at 45°C for 2h, cool to room temperature and filter to obtain a filter residue. The fraction is 75% ethanol solution to wash the filter residue 5 times, put it in a drying oven, and dry it to constant weight at 80°C to obtain N-succinoyl chitosan. Take 8g of sodium alginate and add it to 300mL of deionized water. / min and stirred for 15min, then added 8g mass fraction of 5% sodium periodate solution, and placed in a dark place for oxidation reaction for 24h, after the reaction was completed, 1.5g ethylene glycol was added, stirred for 15min, to obtain the reaction solution, take 12g chlorine Sodium chloride and 300g of absolute ethanol were added to the reaction solution, stirred at 400r / min for 30min, left to stand and precipitated until no precipitation occurred, and then filtered t...
PUM
Login to View More Abstract
Description
Claims
Application Information
Login to View More