Microneedle patch used for resisting senility and removing wrinkles and preparation method of microneedle patch
A micro-needle sticker and needle technology, applied in the field of skin care products, can solve the problems of many adverse reactions, little anti-aging and wrinkle-removing effect, and large trauma, and achieve the effect of removing fine wrinkles, regulating cell metabolism, and small toxic and side effects.
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Embodiment 1
[0033] An embodiment of the present disclosure provides a microneedle patch for anti-aging and anti-wrinkle, which includes a main body supporting component and a functional component. The main body supporting component constitutes a base and needles, and the functional components are dispersed in the base and the needles. The main support component is a hyaluronic acid solution made of biocompatible hyaluronic acid, and the functional components are composed of the following components by weight percentage: 10% ginseng extract, 15% centella asiatica extract , 5% seaweed extract, 10% licorice extract, 5% Tribulus terrestris extract, 10% green tea extract, 10% collagen, 10% donkey-hide gelatin, 8% glycerin, 5% vitamin E, 2% ascorbic acid, 5% allantoin and 5% Tween 60. The needles of the microneedle patch are pyramidal, conical or quasi-conical, the height of the needles is 50 μm, the base diameter is 50 μm, and the distance between the tips of two adjacent needles is 100 μm.
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Embodiment 2
[0041] An embodiment of the present disclosure provides a microneedle patch for anti-aging and anti-wrinkle, which includes a main body supporting component and a functional component. The main body supporting component constitutes a base and needles, and the functional components are dispersed in the base and the needles. The main support component is a pullulan solution made of biocompatible pullulan, and the functional components are composed of the following components by weight percentage: 30% ginseng extract, 25% centella asiatica extract , 3% seaweed extract, 5% licorice extract, 2% Tribulus terrestris extract, 5% green tea extract, 15% collagen, 5% donkey-hide gelatin, 5% glycerin, 2% ascorbic acid , 2% Tween 40 and 1% Tween 80. The needles of the microneedle patch are pyramidal, conical or quasi-conical, the height of the needles is 500 μm, the base diameter is 500 μm, and the distance between the tips of two adjacent needles is 1000 μm.
[0042] The preparation meth...
Embodiment 3
[0049] An embodiment of the present disclosure provides a microneedle patch for anti-aging and anti-wrinkle, which includes a main body supporting component and a functional component. The main body supporting component constitutes a base and needles, and the functional components are dispersed in the base and the needles. The main support component is a maltose solution made of biocompatible maltose, and the functional components are composed of the following components by weight: 20% ginseng extract, 20% centella asiatica extract, 5% Seaweed extract, 5% licorice extract, 5% Tribulus terrestris extract, 5% green tea extract, 15% collagen, 5% donkey-hide gelatin, 10% glycerin, 5% ascorbic acid, 2% Tween 20 and 3% squalene. The needle of the microneedle patch is pyramid-shaped, the height of the needle is 1000 μm, the base diameter is 1000 μm, and the distance between the tips of two adjacent quadrangular pyramid needles is 2000 μm, see figure 1 shown.
[0050] The preparatio...
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