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Compound povidone iodine composition and preparation method thereof

A technology of povidone-iodine and composition, which is applied in the field of compound povidone-iodine composition and its preparation, can solve the problems of clothing dyeing pollution, long volatilization time, slow volatilization, etc., and achieves low production cost and excellent preparation process Simple, Few-Ingredient Effects

Active Publication Date: 2018-12-14
四川悦康源通药业有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0003] The applicant found in the research that the existing iodophors have the problems of deep coloring and long drying time. During use, the dark coloring and slow drying time will easily cause staining and contamination of clothes, etc.

Method used

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  • Compound povidone iodine composition and preparation method thereof
  • Compound povidone iodine composition and preparation method thereof
  • Compound povidone iodine composition and preparation method thereof

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Embodiment Construction

[0039] Below, the applicant will further elaborate the technical solution claimed by the present invention in combination with specific examples, but the scope of protection claimed by the present invention is not limited to the following examples.

[0040] The method for preparing compound povidone-iodine composition is as follows:

[0041] Solution for example:

[0042] Dissolve 5g of povidone iodine in ultrapure water to be configured into a 0.05g / ml povidone iodine solution, get 4ml of povidone iodine solution and mix it with corresponding proportion of solvent, chlorhexidine gluconate, and auxiliary materials, then add ultra Dilute the pure water to 20ml to obtain a 0.01g / ml compound povidone-iodine solution. Wherein, the auxiliary material is one or more of propylene glycol, glycerin, and chitosan; the solvent is one or more of ethanol, ethyl acetate, and ethyl formate.

[0043] Compound povidone-iodine solutions of other concentrations need to be prepared, and differe...

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Abstract

The invention particularly relates to a compound povidone iodine composition. The compound povidone iodine composition comprises, by mass, 0.75 to 1.2 parts of povidone iodine, 5 to 6 parts of chlorhexidine, 4 to 30 parts of a solvent and 0.5 to 5.5 parts of an accessory. The solvent comprises one or more of ethanol, ethyl acetate and ethyl formate. The accessory comprises one or more of propyleneglycol, glycerin and chitosan. Through rational combination of the existing conventional raw materials, compared with the existing iodophor or iodophor-containing medicament, the product has the characteristics of light color, fast volatilization and small irritation and has the same sterilization and disinfection functions.

Description

technical field [0001] The invention relates to the technical field of disinfection, in particular to a compound povidone-iodine composition and a preparation method thereof. Background technique [0002] Povidone-iodine (PVP-I, referred to as PI) is a compound of polyvinylpyrrolidone (PVP) and iodine, also known as iodophor, containing 9-12% of available iodine, and is a broad-spectrum strong bactericidal disinfectant. Viruses, bacteria, fungi and mold spores all have a strong killing effect. It has little irritation to skin, low toxicity and long-lasting effect. Safe and easy to use. It is basically non-irritating to tissues, and is used for disinfection of skin and mucous membranes, such as cleaning before surgery, disinfection of surgical sites and wounds. Its bactericidal principle is mainly through the release of free iodine hydrate to play a bactericidal effect. Povidone is hydrophilic and is the carrier for transporting iodine to the cell membrane. When the compou...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/18A61P31/02A61K31/155
CPCA61P31/02A61K31/155A61K33/18A61K2300/00
Inventor 曾锐李燕芳
Owner 四川悦康源通药业有限公司
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