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Absorbable membrane, preparation method and application of absorbable membrane and dental implant

A technology of absorbing film and liquid film, applied in the field of medicine, can solve problems such as poor regeneration effect, and achieve the effect of shortening the treatment period, high mechanical strength and fast growth

Inactive Publication Date: 2019-01-22
张浩淼
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The purpose of the present invention is to provide an absorbable film, its preparation method and application, and a dental implant, which aims to improve the problem of poor regeneration effect existing in the existing masking film induced regeneration

Method used

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  • Absorbable membrane, preparation method and application of absorbable membrane and dental implant
  • Absorbable membrane, preparation method and application of absorbable membrane and dental implant
  • Absorbable membrane, preparation method and application of absorbable membrane and dental implant

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preparation example Construction

[0063] The preparation method of the absorbable film provided by the embodiment of the present invention can obtain a film with a uniform texture, which can be applied to induce the regeneration of some biological tissues, for example, to induce bone regeneration; it can induce better, and can be used for large-area tissues damage.

[0064] The present invention also provides an application of the above-mentioned absorbable film, the application of the absorbable film in inducing the regeneration of biological tissue, and the biological tissue includes bone, body surface, mucous membrane of digestive tract or mucous membrane of respiratory tract.

[0065] The absorbable film has the effect of sustained drug release, and is easily absorbed by the above-mentioned biological tissues, so it can be used to induce the regeneration of biological tissues.

[0066] The biological tissue mentioned above can be bone, body surface (such as skin), mucous membrane of digestive tract (such a...

Embodiment 1

[0074] This embodiment provides an absorbable film, which is mainly prepared by the following methods:

[0075] Dissolving polylactic acid glycolic acid and lovastatin in dichloromethane to prepare a mixed solution; spreading the mixed solution to obtain a liquid film, volatilizing the dichloromethane in the liquid film to obtain an absorbable film;

[0076] The mass ratio of polylactic acid glycolic acid and lovastatin is 10:0.8, and the ratio of polylactic acid glycolic acid and dichloromethane is 0.78g / ml.

[0077] The absorbable film provided in this embodiment can be applied to induce the regeneration of biological tissue, and the biological tissue includes bone, body surface, mucous membrane of digestive tract or mucous membrane of respiratory tract.

[0078] Further, the absorbable film is used to induce bone regeneration, to induce alveolar bone regeneration.

Embodiment 2

[0080] This embodiment provides an absorbable film, which is mainly prepared by the following method:

[0081] Dissolving polylactic acid glycolic acid and lovastatin in dichloromethane to prepare a mixed solution; spreading the mixed solution to obtain a liquid film, volatilizing the dichloromethane in the liquid film to obtain an absorbable film;

[0082] The mass ratio of polylactic acid glycolic acid and lovastatin is 10:1.2, and the ratio of polylactic acid glycolic acid and dichloromethane is 0.82g / ml.

[0083] The absorbable film provided in this embodiment can be applied to induce the regeneration of biological tissue, and the biological tissue includes bone, body surface, mucous membrane of digestive tract or mucous membrane of respiratory tract.

[0084] Further, the absorbable film is used to induce bone regeneration, to induce alveolar bone regeneration.

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Abstract

The invention relates to the field of medicine, in particular to an absorbable membrane, a preparation method and application of the absorbable membrane and a dental implant. The preparation method ofthe absorbable membrane comprises the following steps that polylactic acid glycolic acid and lovastatin are dissolved in a solvent to prepare a mixed solution; alternatively, the polylactic acid glycolic acid and fluvastatin are dissolved in a solvent to prepare a mixed solution; and the mixed solution is spread to obtain a liquid membrane, and the solvent in the liquid membrane is volatilized toobtain the absorbable membrane. According to the preparation method, the membrane with uniform texture can be obtained, and the membrane can better induce tissue regeneration function and can be usedfor treating large-area tissue damage. The absorbable membrane has high mechanical strength with more than 15 MPa, and is sufficient to support new tissue formation. The dental implant is beneficialto the dental implant to be more appropriate to alveolar bone in the later stage and shortens the treatment period.

Description

technical field [0001] The invention relates to the field of medicine, in particular to an absorbable film, its preparation method and application, and a dental implant. Background technique [0002] The key step in the induced regeneration technique lies in the application of the masking film. Traditional membranes are divided into absorbable membranes and non-absorbable membranes (pure titanium membranes). Because non-absorbable membranes require secondary surgery to remove them, absorbable membranes are commonly used in bone regeneration-induced surgery. In the past, our absorbable membrane was mainly collagen membrane, but the regeneration effect of collagen membrane induced regeneration was not good. Contents of the invention [0003] The purpose of the present invention is to provide an absorbable film, its preparation method and application, and a dental implant, which aims to improve the problem of poor regeneration effect existing in the existing masking film in...

Claims

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Application Information

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IPC IPC(8): A61L27/34A61L27/54A61L27/58
CPCA61L27/34A61L27/54A61L27/58A61L2300/204A61L2300/216A61L2300/412A61L2300/604A61L2430/12C08L67/04
Inventor 张浩淼
Owner 张浩淼
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