Method for manufacturing micro-channel rapidly on basis of 3D printing

A technology of three-dimensional printing and micro-channels, which is applied in chemical instruments and methods, laboratory containers, laboratory utensils, etc., can solve the problems of low precision of micro-channels, complex process, high cost, etc., and achieve good packaging effect , simple process and low cost

Inactive Publication Date: 2019-03-01
GUANGDONG UNIV OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, at present, the cost of microparticle lithography technology and 3D inkjet printing technology is relatively high, while the precision of the microfluidic channels directly printed by fused deposition modeling technology is not high; Packaging Difficulty

Method used

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  • Method for manufacturing micro-channel rapidly on basis of 3D printing
  • Method for manufacturing micro-channel rapidly on basis of 3D printing
  • Method for manufacturing micro-channel rapidly on basis of 3D printing

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] figure 1 It is a process flow diagram of the present invention, a method for rapidly manufacturing microchannels based on three-dimensional printing, comprising the following steps:

[0038] (1) Using the computer-aided design software solidworks to design the model of the Y-shaped microchannel, and design a boss at the end of the channel.

[0039] (2) Then save the model as stl file format, import it into the slicing software, generate the printing path trajectory of the 3D printer, copy the generated gcode file to the 3D printer, and prepare for printing.

[0040] (3) The printing material is PVA water-soluble filament, such as figure 2 shown, figure 2 Schematic diagram of the 3D printing process. Among them, 1-PVA wire, 2-printing nozzle, 3-printing substrate. Using an FDM printer, polyvinyl alcohol (PVA) was printed on the printing substrate polymethyl methacrylate (PMMA) according to the designed track to form a PVA flow channel mask with a width of 200 μm. ...

Embodiment 2

[0044] (1) Use the computer-aided design software solidworks to design the model of the curved micro-channel, and design the boss at the end of the channel.

[0045] (2) Then save the model as stl file format, import it into the slicing software, generate the printing path trajectory of the 3D printer, copy the generated gcode file to the 3D printer, and prepare for printing.

[0046] (3) The PVA water-soluble material is printed on the printing substrate polyethylene terephthalate (PET) according to the design track by using the FDM type printer to form a PVA flow channel mask with a width of 300 μm.

[0047] (4) After removing the printing substrate on which the PVA runner mask is deposited, pour the UV-curable adhesive Lantian 9307 onto the PET of the printing substrate to completely cover the runner, but do not miss the boss at the end of the runner.

[0048] (5) After the glue is cured, put the entire microfluidic chip into a cleaning machine with ultrasonic power of 50 k...

Embodiment 3

[0050](1) Using the computer-aided design software solidworks to design a model of a single annular microchannel, and design a boss at the end of the channel.

[0051] (2) Then save the model as stl file format, import it into the slicing software, generate the printing path trajectory of the 3D printer, copy the generated gcode file to the 3D printer, and prepare for printing.

[0052] (3) Using an FDM printer to print the PVA water-soluble material on the glass of the printing substrate according to the design track, to make a PVA flow channel mask with a width of 250 μm.

[0053] (4) After removing the printing substrate on which the PVA runner mask is deposited, pour the epoxy resin AB glue on the glass of the printing substrate to completely cover the runner, but do not miss the boss at the end of the runner.

[0054] (5) After the glue is cured, put the entire microfluidic chip into a cleaning machine with ultrasonic power of 40 kHz and water temperature of 80 °C for 9 h...

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Abstract

The invention belongs to the technical field of micro-channel manufacture and discloses a method for manufacturing a micro-channel rapidly on the basis of 3D printing. The method comprises following specific steps: S1, the shape of the channel is designed by computer-aided software and stored as an STL (standard template library) model; S2, the STL model is converted into a printing path track ofa 3D printer by slicing software; S3, a PVA (polyvinyl acetate) water-soluble material is printed on a printing substrate by 3D printing according to the designed track, and a channel mask is manufactured; S4, the printing substrate is taken down, glue is poured to the printing substrate, and then the printing substrate is left to stand; S5, cleaning is performed: after the glue is cured, the whole body is put in water and subjected to ultrasonic cleaning, PVA is dissolved, and the micro-channel is manufactured. By means of the water-soluble 3D printing material, the required micro-channel mask is manufactured with the 3D printing technology and encapsulated with glue. The method does not need chemical processes such as etching and the like and has the advantages of high flexibility, low cost and good encapsulating effect.

Description

technical field [0001] The invention belongs to the technical field of micro-channel fabrication, and more particularly, relates to a method for rapidly fabricating a micro-channel based on three-dimensional printing. Background technique [0002] In the research and application of microfluidic chips, the first is the production of microfluidic chips, that is, microfluidic channels with various layouts are processed on materials such as quartz, glass, organic polymers, etc., and then covered and bonded to produce microfluidic chips. get chips. Although the fabrication and manufacture of microfluidic chips based on silicon and glass substrates are gradually mature, the fabrication of microfluidic chips based on high polymer organic substrates, which has attracted widespread attention, is still in the stage of exploration and development. The main obstacle to the promotion and application of microfluidic chips at present is the high cost of chip fabrication. The microfluidic...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B01L3/00B33Y10/00
CPCB01L3/502707B33Y10/00
Inventor 王晗陶旭蕾房飞宇
Owner GUANGDONG UNIV OF TECH
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