Anti-bacterial medical dressing and preparation method thereof

Abstract

The invention relates to the medical field, and discloses an anti-bacterial medical dressing and a preparation method thereof. The preparation method for the anti-bacterial medical dressing comprisesthe following steps of: enabling a medical aseptic dressing and dopamine hydrochloride to be mixed in a trometamol solution, adding an AgNO3 water solution, in a stirring condition, preparing the silver-loaded anti-bacterial medical dressing at a normal temperature and a dark place. The method for preparing the anti-bacterial medical dressing has the advantages of being simple, moderate in condition without tedious experimental procedures, without an additional reducing agent, and without a high temperature condition, can be performed at a normal temperature, and capable of maintaining a structure and ingredients of the original dressing, through the chelation action of polydopamine and nano-silver, the nano-silver is fixed on a polydopamine nano through a chemical bond, and the polydopamine nano film is tightly adhered to the dressing, so that the obtained anti-bacterial medical dressing is capable of slowly releasing silver ions, achieving the continuous anti-bacterial effect, and reducing a release quantity of the silver ions, and safer while guaranteeing the effective anti-bacterial effect.

Description

technical field [0001] The invention relates to the medical field, in particular, the invention relates to an antibacterial medical dressing and a preparation method thereof. Background technique [0002] Medical dressing is a kind of medical wound healing material. By temporarily covering the wound, it prevents harmful substances such as bacteria and microorganisms from invading the wound, and at the same time reduces the loss of body fluids, providing favorable conditions for wound healing. Antibacterial functional medical dressings can reduce the rate of wound infection and accelerate wound healing, etc., and have attracted much attention in the field of medical dressings and have a good application prospect. Among them, silver-loaded medical dressings combine the advantages of nano-silver with low antibacterial toxicity, broad-spectrum antibacterial properties and resistance to drug resistance, and have become the most promising type of antibacterial dressings in medical...

AI Technical Summary

Problems solved by technology

[0003] At present, there are mainly two methods for the preparation of silver-loaded medical dressings. One is to prepare nano-silver particles first, and then mechanically blend them with the dressing to obtain a silver-loaded dressing; There is no strong connection method, which leads to the disadvantages of nano-silver easy to fall off, the concentration of released nano-silver is too high and the release time is short; another method is to restore nano-silver in situ, that is, after mixing the dressing with silver ions, through reduction At a certain temperature, silver ions can be reduced to nano-silver with an agent, so as to obtain a silver-loaded dressing. This method is relatively simple and convenient, but it still has certain problems. First: most of the methods are carried out under high temperature conditions, which may It will cause some damage to the structure of the dressing; second: additional reducing agent needs to be added, and the subsequent removal of the reducing agent is cumbersome, which increases the cost of the experiment; third, nano-silver is loaded on the surface of the dressing only by weak physical adsorption, and it is easy to fall off

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