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A traditional Chinese medicine composition for treating pulmonary interstitial fibrosis, traditional Chinese medicine free decoction granules and application thereof

A technology for pulmonary interstitial fibrosis and decoction-free granules, applied in the field of traditional Chinese medicine, can solve problems such as further evaluation, photosensitivity, elevated liver enzymes, etc., and achieve the effect of regulating the immune function of the body

Active Publication Date: 2021-08-06
陕西省中医医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Pirfenidone, nintedanib, and antacid drugs are recommended for the treatment of pulmonary interstitial fibrosis by Western medicine. Oxygen therapy, mechanical ventilation, pulmonary rehabilitation, and lung transplantation can also be used for treatment. However, the clinical efficacy, safety and adaptability of Western medicine Further evaluation is needed, and western medicines are expensive, and are prone to adverse reactions such as elevated liver enzymes, photosensitivity, rash, fatigue, osteoporosis, and gastrointestinal disorders
Western medicine treatment summed up: basically no medicine available

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0062] Example 1: The preparation of Chinese medicine composition:

[0063] Weigh raw astragalus 9g, Codonopsis 9g, Ophiopogon japonicus 6g, wax gourd kernel 10g, reed root 10g, raw coix seed 9g, peach kernel 5g, honeysuckle 6g, angelica 6g, raw licorice 2g.

Embodiment 2

[0064] Example 2: The preparation of Chinese medicine composition:

[0065] Weigh 20g of raw astragalus, 12g of codonopsis, 9g of Radix Ophiopogon japonicus, 12g of wax gourd kernels, 12g of reed root, 20g of raw coix kernels, 8g of peach kernels, 10g of honeysuckle, 10g of angelica, and 4g of raw licorice.

Embodiment 3

[0066] Example 3: The preparation of Chinese medicine composition:

[0067] Weigh 30g of raw astragalus, 15g of Codonopsis pilosula, 12g of Radix Ophiopogon japonicus, 15g of wax gourd kernels, 15g of reed root, 30g of raw coix kernels, 10g of peach kernels, 15g of honeysuckle, 15g of angelica, and 6g of raw licorice.

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PUM

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Abstract

The invention discloses a traditional Chinese medicine composition for treating pulmonary interstitial fibrosis, traditional Chinese medicine decoction-free granules and applications thereof, belonging to the technical field of traditional Chinese medicine. The traditional Chinese medicine composition is composed of the following raw materials by weight: 9-30 parts of raw Astragalus membranaceus, 9-15 parts of Codonopsis pilosula, 6-12 parts of Ophiopogon japonicus, 10-15 parts of winter melon kernel, 10-15 parts of reed rhizome, 10-15 parts of raw coix coix 9‑30 parts of kernels, 5‑10 parts of peach kernels, 6‑15 parts of honeysuckle, 6‑15 parts of angelica and 2‑6 parts of raw licorice. The traditional Chinese medicine decoction-free granule consists of the above-mentioned single-flavor traditional Chinese medicine formula granules. Application of traditional Chinese medicine composition and traditional Chinese medicinal decoction granule in preparation of medicine for treating pulmonary interstitial fibrosis. The invention has the following advantages: nourishing qi and nourishing yin, resolving phlegm and expelling blood stasis; having anti-inflammatory, anti-oxidation, anti-angiogenesis, anti-coagulation, anti-thrombosis and anti-platelet aggregation functions; and having the function of regulating the body's immune function.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a traditional Chinese medicine composition for treating pulmonary interstitial fibrosis, traditional Chinese medicine decoction-free granules and applications thereof. Background technique [0002] Pulmonary interstitial fibrosis (PIF) is a progressive and progressive fatal diffuse lung disease involving pulmonary interstitium, alveoli and / or bronchioles. Hemoxemia, pulmonary function restrictive ventilatory disorder and decreased diffusion function are the clinical features, and the clinical manifestations are progressive dyspnea, shortness of breath, dry cough, etc., and most of the patients eventually die due to respiratory failure. Pulmonary interstitial fibrosis is divided into two categories: idiopathic pulmonary fibrosis (IPF) and secondary pulmonary fibrosis (IPF). Pulmonary fibrosis is often secondary to immune system diseases such as rh...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8994A61K9/16A61P11/00
CPCA61K9/16A61K36/232A61K36/344A61K36/355A61K36/42A61K36/481A61K36/484A61K36/736A61K36/8968A61K36/899A61K36/8994A61P11/00A61K2300/00
Inventor 李猛马战平王志梅黄刚山萌
Owner 陕西省中医医院
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