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Chinese herbal medicine composition for treating porcine epizootic diarrhea

A technology of porcine epidemic diarrhea and Chinese herbal medicine composition, which is applied in the direction of drug combination, drug delivery, and medical formula, which can solve the problems of low vaccine effect and high cost of prevention and treatment, and achieve no drug resistance, no drug residue, and small toxic and side effects Effect

Inactive Publication Date: 2019-05-31
INST OF ANIMAL HUSBANDRY & VETERINARY MEDICINE ANHUI ACAD OF AGRI SCI
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  • Summary
  • Abstract
  • Description
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  • Application Information

AI Technical Summary

Problems solved by technology

[0006] In order to solve the problems of low efficacy of current porcine epidemic diarrhea vaccine and high cost of prevention and control, the invention provides a Chinese herbal medicine composition for preventing and treating porcine epidemic diarrhea disease

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Select pig farms with piglet epidemic diarrhea, select 60 pigs with symptoms of porcine epidemic diarrhea at the age of 20 to 25 days, and use porcine epidemic diarrhea virus antigen to detect colloidal gold test strips to test positive, isolate and raise them separately, and divide them into two groups. 30 pigs in each group, one group was treated by adding traditional Chinese medicine compound powder in the feed at a mass ratio of 3%, and the other group was a blank control group; in addition, 20-25-day-old porcine epidemic diarrhea without diarrhea symptoms were selected at the same time. A group of 100 pigs were raised separately in isolation and divided into four groups, 25 pigs in each group. The three groups added traditional Chinese medicine compound powder to the feed at a mass ratio of 1%, 2%, and 3% for prevention. Group 1 was a blank control group. The experiment time is 5 days. According to the dose of 4mL / kg, it was divided into two parts, and the pigs dia...

Embodiment 2

[0033] Select pig farms with piglet epidemic diarrhea, select 40 pigs with symptoms of porcine epidemic diarrhea at the age of 15 to 20 days, and use porcine epidemic diarrhea virus antigen to detect colloidal gold test strips to test positive, isolate and raise them separately, and divide them into two groups. Group, 20 heads in each group, one group was fed with traditional Chinese medicine compound decoction one hour before feeding. The other group was the blank control group, without administration.

[0034]The results showed that: in pigs with porcine epidemic diarrhea disease, the cure rate of the Chinese medicine compound decoction treatment group was 90%, and the cure rate of the untreated group was 30%.

[0035] Clinical practice shows that the efficacy of each Chinese medicine in the traditional Chinese medicine compound combination of the present invention is not only synergistic, but also complementary to each other. It mainly focuses on clearing away heat and damp...

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Abstract

The invention discloses a Chinese herbal medicine composition for treating porcine epizootic diarrhea. The Chinese herbal medicine composition is prepared from, by weight, 3 parts of radix sophorae flavescentis, 2 parts of fructus evodiae, 2 parts of fructus gardeniae, 2 parts of concha margaritifera, 1 part of pomegranate bark, 1 part of fructus aurantii, 1 part of rhizoma atractylodis, 1 part oflicorice roots and 1 part of folium isatidis. All the raw materials are prepared into powder or a decoction according to a conventional pharmaceutical preparation technology. The Chinese herbal medicine composition is used for treating porcine epizootic diarrhea and is safe, green, low in side and toxic effect, free of drug residue and not prone to drug resistance, and the Chinese herbal medicinecomposition has an inhibition effect on growth and reproduction of various diarrhea pathogens. The functions of all the traditional Chinese medicine materials in the formula cooperate and are mutually complemented, the Chinese herbal medicine composition has the main functions of clearing away heat, drying dampness and relieving diarrhea and has the accessory functions of regulate the flow of vital energy and middle energizer, invigorating spleen and supplementing Qi, and the effect of treating the porcine epizootic diarrhea is remarkable; the materials are easy to obtain, the price is low, the preparation technology is simple and easy to operate, and large-scale application and popularization in a livestock farm are facilitated.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a Chinese herbal medicine composition for treating porcine epidemic diarrhea. Background technique [0002] Porcine epidemic diarrhea (PED) is an enteric infectious viral disease caused by porcine epidemic diarrhea virus (PEDV), characterized by watery diarrhea, vomiting and dehydration. The epidemic characteristics, clinical symptoms and pathological changes of this disease are very similar to those of infectious gastroenteritis. Porcine epidemic diarrhea first occurred in the UK in 1971, and there have been reports on the isolation and identification of PEDV in my country since the early 1980s. It mainly occurs in winter, and can also occur in summer. In my country, December to February of the following year is the season of high incidence of this disease. [0003] PEDV is a member of the genus Coronaviridae in the Coronaviridae family. Pigs ...

Claims

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Application Information

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IPC IPC(8): A61K36/855A61P1/12A61K9/14A61K9/00A61K35/618
Inventor 潘孝成赵瑞宏张丹俊沈学怀戴银胡晓苗周学利候宏艳
Owner INST OF ANIMAL HUSBANDRY & VETERINARY MEDICINE ANHUI ACAD OF AGRI SCI
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