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Shape memory wound closing device

A closed device and memory polymer technology, applied in the field of medical devices, can solve the pain of the injured and other problems, and achieve the effect of good continuity, simple steps and fast process.

Pending Publication Date: 2019-06-04
NANJING SKY LONG PHARMA +5
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

No matter what kind of suture, in the absence of anesthesia, the existing suture technology will cause a certain degree of pain to the injured

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] The manufacture and use of the device of this embodiment include the following steps:

[0026] Step 1, take polyurethane (PU) as raw material, dissolve it in chloroform-dimethylformamide (DMF) mixed solvent with a concentration ratio of 1:1, and prepare a polyurethane-chloroform-DMF solution with a polyurethane concentration of 20% .

[0027] Step 2, put the prepared polyurethane-chloroform-DMF solution into the electrospinning machine, and then spin the film with the parameters of spinning voltage 6kV, drum speed 700 rpm / min, and spinning distance 6 cm, and cut it into a length of 30 mm. Several long polyurethane strips with a width of 3 mm and a thickness of 0.5 mm (that is, fiber membrane 1).

[0028] Step 3, paste several long polyurethane strips on the non-adhesive surface of the medical adhesive tape 2 through the adhesive material layer on one side. For the specific arrangement, refer to figure 1 , the shape memory wound closure device was fabricated.

[0029]...

Embodiment 2

[0032] The manufacture and use of the device of this embodiment include the following steps:

[0033] Step 1, using polyurethane (PU) as raw material, dissolve it in a mixed solution of acetone and dimethylformamide (V / V) at a concentration ratio of 1:1 (V / V), and prepare polyurethane-acetone-two Methylformamide solution.

[0034] Step 2, put the prepared polyurethane-acetone-dimethylformamide solution into the electrospinning machine, and then spin the film with the parameters of spinning voltage 6 kV, drum speed 500 rpm / min, and spinning distance 8 cm Afterwards, several long polyurethane strips with a length of 28 mm, a width of 2.2 mm and a thickness of 0.15 mm are cut.

[0035] Step 3, heat several long strips of polyurethane strips to 50°C and pre-stretch them by 30%, and then paste them on the non-adhesive surface of the medical adhesive tape. For the specific arrangement, refer to figure 1 , the shape memory wound closure device was fabricated.

[0036] Step 4, refe...

Embodiment 3

[0040] The manufacture and use of the device of this embodiment include the following steps:

[0041] Step 1, using polycaprolactone (PCL) as a raw material, dissolve it in dimethylformamide: chloroform 1:1 (V / V) mixed solvent, and prepare polycaprolactone with a polycaprolactone concentration of 18%. Lactone-dimethylformamide-chloroform solution.

[0042] Step 2, put the prepared polycaprolactone-dimethylformamide-chloroform solution into the electrospinning machine, and then use the parameters of spinning electricity 8 kV, drum speed 600 rpm / min, and spinning distance 10 cm After weaving out the film, cut a number of elongated polycaprolactone strips with a length of 28 mm, a width of 2.2 mm, and a thickness of 0.15 mm.

[0043] Step 3. Pre-stretch several long polycaprolactone strips by 30% at room temperature and paste them on the non-adhesive surface of the medical adhesive tape. For the specific arrangement, refer to figure 1 , the shape memory wound closure device was...

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Abstract

The invention belongs to a medical apparatus, and relates to a shape memory wound closing device. The shape memory wound closing device comprises a fiber membrane which is manufactured through an electrostatic spinning method and by using shape memory polymeric materials as raw materials, wherein the fiber membrane has a stretching pre-deformation condition; and an adhering material layer is compounded on one or more side surfaces of the fiber membrane. When being used, the shape memory wound closing device is adhered to the wound in a crossing manner, and then the shape memory effect is activated, so that the shape memory wound closing device is contracted and recovered, then the wound tissue is dragged, and the wound is closed. The shape memory wound closing device disclosed by the invention can replace a conventional medical suture to perform closing treatment on the wound, so that the operation efficiency of wound closing can be improved, the difficulty can be reduced, and the painof a patient is reduced.

Description

technical field [0001] The invention belongs to medical equipment, and relates to a shape memory wound closure device. Background technique [0002] After severe or quasi-plastic deformation, shape memory materials (including some alloys and polymer materials, etc.) can restore their original shape under appropriate stimulation. This phenomenon is called the shape memory effect. The main factors affecting shape memory polymers are temperature, light or humidity. Generally, according to the different properties of different polymers, the deformation of shape memory polymers can be at room temperature or at its transition temperature (glass transition temperature or melting temperature). For thermally actuated shape-memory polymers, heating can restore them from their deformed form to their original shape. For chemically actuated shape memory polymers, the recovery of the deformation is triggered by exposure to a specific chemical solution. [0003] Electrospinning technolo...

Claims

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Application Information

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IPC IPC(8): A61B17/08A61L17/00
Inventor 魏民房飞宇王韬熹王华权黄为民
Owner NANJING SKY LONG PHARMA
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