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Preparation process of Scutellaria baicalensis and Coptis chinensis antidiarrheal enteric coated pellets

A technology of enteric-coated pellets and preparation process, which is applied to medical preparations containing active ingredients, drug delivery, plant raw materials, etc., and can solve problems affecting the efficacy of drugs and the destruction of active ingredients

Inactive Publication Date: 2019-06-04
珠海天成中药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, the hydrochloric acid in the gastric juice will often destroy the active ingredients of the drug, thus affecting the efficacy of the drug.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0007] Facility Example 1

[0008] Take 3 parts of Scutellaria baicalensis, 0.5 parts of Coptis chinensis, 7 parts of zinc oxide, and 1 part of licorice. The four medicinal materials were pulverized respectively through a 120-mesh sieve. Among them, the content of baicalin in the fine powder of Scutellaria baicalensis is 10%, the content of berberine in the fine powder of Coptis chinensis is 8%, and the content of glycyrrhizic acid in the fine powder of licorice is 2%. Mix the four kinds of fine powders evenly, add 2 parts of medicinal dextrin and appropriate amount of tap water to prepare a soft material, and make pellets with a particle size of 1-1.5mm, dry, and sieve for granulation. The granulated pellets are coated with an enteric coating by acrylic resin II spraying method in a water chestnut-shaped coating pan, dried and packed.

[0009] Facility example 2

[0010] Take 3 parts of Scutellaria baicalensis, 2 parts of Coptis chinensis, 6 parts of zinc oxide, and 2 part...

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PUM

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Abstract

The invention discloses a preparation process of Scutellaria baicalensis and Coptis chinensis enteric coated pellets. A prescription is composed of Scutellaria baicalensis, Coptis chinensis, zinc oxide and licorice. The four medicinal materials are respectively pulverized and sieved by a 120-mesh sieve to prepare the pellets, and the pellets are then coated with enteric coating. The four medicinalmaterials in the prescription act together, which can prevent diarrhea of piglets and reduce the mortality. At the same time, the enteric coated dosage form not only avoids the damage of zinc oxide by gastric acid, but also avoids the influence of the bitterness of Coptis chinensis on the feeding of piglets.

Description

technical field [0001] The "preparation process of Erhuang Zhixie enteric-coated pellets" of the present invention belongs to the field of traditional Chinese medicine preparations, in particular to the field of veterinary traditional Chinese medicine enteric-coated pellet preparations. Background technique [0002] Traditional oral preparations of traditional Chinese medicine, such as pills, powders, granules, tablets, capsules and liquid preparations, mostly disintegrate or dissolve in the stomach, irritating the gastric mucosa and affecting the patient's appetite. Especially Coptis chinensis and other traditional Chinese medicines with cold and cold properties, long-term use can hurt the stomach qi, affect the function of the spleen and stomach, and damage people's righteousness. In addition, the hydrochloric acid in the gastric juice often destroys the active ingredients of the drug, thereby affecting the efficacy of the drug. The intestine is the main site of drug abso...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/718A61K9/32A61P1/12A61K33/30
Inventor 黄竹青
Owner 珠海天成中药有限公司