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Preparation method of psicose crystals

A technique for psicose and crystals, which is applied in the production field of psicose crystals, can solve problems such as troublesome actual production, difficult operation, complicated process, etc., achieves small particle size distribution range, improves crystallization yield, and simplifies preparation process Effect

Active Publication Date: 2019-12-31
SHANDONG BAILONG CHUANGYUAN BIO TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] All of the above technologies have used repeated heating and cooling processes to prepare allulose crystals. The process is complex and difficult to operate, which brings troubles to actual production, and the generated crystals have small particle size and low yield.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0050] The psicose liquid is purified by enzymatic conversion, wherein the allulose has a purity of 32%. Using SSMB chromatographic separation system, the mass ratio of water to material is 1.5, the temperature is 55°C, the purity after purification is 99.1%, and it is concentrated to a solid content of 85%, adding 1% seed crystals, keeping the temperature at 45°C, and the vacuum degree at -0.04 MPa, the stirring speed is 15 rpm, crystallization for 40 hours, after centrifugation, it is washed with cold water at 4°C, and dried in a fluidized bed at 60°C. After screening, the percentage of crystals above 20 mesh is 8%, and the crystals of 20-40 mesh are 61%, 20.5% for 40-60 mesh crystals, 10.5% for 60 mesh or less crystals, 70% crystal yield, and 99.6% crystal purity.

Embodiment 2

[0052] The psicose liquid is purified by enzymatic conversion, wherein the allulose has a purity of 30%. Using SSMB chromatographic separation system, the mass ratio of water to material is 1.6, the temperature is 60°C, the purity after purification is 99.0%, and it is concentrated to a solid content of 75%, adding 0.5% seed crystals, keeping the temperature at 35°C, and the vacuum degree at -0.05 MPa, the stirring speed is 10 rpm, crystallization for 60 hours, after centrifugation, it is washed with cold water at 4°C, and dried in a fluidized bed at 40°C. After screening, the percentage of crystals above 20 mesh is 10%, and the crystals of 20-40 mesh are 58%, 22% for 40-60 mesh crystals, 10% for 60 mesh or less crystals, 65% crystal yield, and 99.8% crystal purity.

Embodiment 3

[0054] The psicose liquid is purified by enzymatic conversion, and the purity of allulose is 28%. Using SSMB chromatographic separation system, the mass ratio of water to material is 1.8, the temperature is 58°C, the purity after purification is 99.2%, and it is concentrated to a solid content of 80%, adding 0.5% seed crystals, keeping the temperature at 45°C, and the vacuum degree at -0.05 MPa, the stirring speed is 12 rpm, crystallization for 50 hours, after centrifugation, it is washed with cold water at 4°C, and dried in a fluidized bed at 50°C. After screening, the percentage of crystals above 20 mesh is 12%, and the crystals of 20-40 mesh are 63%, 15% for 40-60 mesh crystals, 10% for 60 mesh or less crystals, 61% crystal yield, and 99.7% crystal purity.

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Abstract

The present invention relates to a preparation method of psicose crystals. The preparation method comprises the following steps: carrying out chromatographic separation of psicose liquid after an enzymatic conversion is finished and purifying the psicose to a purity of 98.5% or more; concentrating the purified psicose to a solid content by mass of 75-85% and conducting rapid cooling to 35-45 DEG C; adding seed crystals, keeping temperature at 35-45 DEG C and a vacuum degree of -0.03 to -0.09 MPa, and performing constant-temperature evaporative crystallization; and performing centrifugal separation to obtain crystals with a particle size larger than 60 meshes, and conducting washing and drying to obtain the psicose crystals. The technical means of controllable evaporation, constant-temperature crystallization, etc. are used to solve a problem that fine crystals are generated under a condition of high supersaturation degree, greatly improve particle diameter of the crystals, enable one-time crystallization yield to reach 60-70%, greatly simplify preparation processes and also improve crystallization yield.

Description

technical field [0001] The invention belongs to the technical field of preparation of functional sugars, and in particular relates to a production method of allulose crystals. Background technique [0002] Allulose (D-psicose) is a six-carbon sugar with a very low content in nature, and it is an epimer at the C-3 position of D-fructose. D-Psicose is difficult to digest and absorb, and hardly provides energy for life activities, so it is a very useful low-calorie sweetener. In the field of medicine and health, D-psicose can inhibit fatty liver enzymes and intestinal α-glucosidase, thereby reducing the accumulation of body fat and inhibiting the rise of blood sugar concentration. Adding D-psicose to meals can reduce postprandial blood glucose response and improve insulin sensitivity and glucose tolerance. In addition, compared with other rare sugars, D-psicose can more effectively scavenge active oxygen free radicals. In mouse experiments, it was found that D-psicose can pr...

Claims

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Application Information

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IPC IPC(8): C07H1/06C07H3/02
CPCC07H1/06C07H3/02
Inventor 邵先豹干昭波禚洪建刘伟李方华张明站杨腾腾
Owner SHANDONG BAILONG CHUANGYUAN BIO TECH
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