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Medicament for resisting aquatic pathogenic bacillus mycoides and preparation method thereof

A Bacillus mycoides, pathogenic technology, applied in the field of aquaculture drugs, can solve the problems of lack of control drugs, unreported literature and materials, etc., and achieve the effects of improving health level, less toxic and side effects, and reducing the amount of use

Active Publication Date: 2020-01-10
SHANGHAI OCEAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0003] However, the control drugs for this bacteria are extremely scarce at present, and there are no reports in the existing literature

Method used

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  • Medicament for resisting aquatic pathogenic bacillus mycoides and preparation method thereof

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Embodiment 1

[0021] The medicine for resisting aquatic pathogenic Bacillus mycoides is a compound preparation of traditional Chinese and western medicine, which is an aqueous solution containing ebony extract, wolfberry extract, gentamicin sulfate and didecyldimethylammonium chloride, wherein , the crude drug concentration of ebony extract is 0.1g / ml, the crude drug concentration of wolfberry extract is 0.3g / ml, the concentration of didecyldimethylammonium chloride is 0.08g / ml, the concentration of gentamicin sulfate The concentration is 0.5 g / ml.

[0022] The preparation method is as follows:

[0023] Firstly, the ebony extract and wolfberry extract were prepared respectively, and then the obtained ebony extract and wolfberry extract were mixed with didecyldimethylammonium chloride solution and gentamicin sulfate, as follows.

[0024] The steps of preparing the ebony extract: according to the ratio of adding 10 g of ebony to every 100 ml of water, soak the ebony in water for 30 minutes a...

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Abstract

The invention relates to a medicament for resisting aquatic pathogenic bacillus mycoides. The medicament being a Chinese-and-western-medicine compound preparation comprises traditional Chinese medicine extracts including a dark plum extract and a Chinese wolfberry fruit extract and western medicines including didecyl dimethyl ammonium chloride and gentamicin sulfate. High-efficiency and quick-acting antibacterial advantages of western medicines and characteristics of drug resistance prevention and low toxic and side effects of the traditional Chinese medicine preparations are combined scientifically. More important, the inventor accidentally finds that coordinated promotion can be realized by compounding the dark plum extract, the Chinese wolfberry fruit extract, the didecyl dimethyl ammonium chloride and gentamicin sulfate that have the certain concentrations to effectively resist the aquatic pathogenic bacillus mycoides, so that the use amount of medicines, especially western medicines, is reduced in specific aquatic application and the cost is lowered; and the toxic and side effects of medicine usage to the breeding environment are reduced and the health level of aquatic animalsis improved.

Description

technical field [0001] The invention relates to a medicine for resisting aquatic pathogenic Bacillus mycoides and a preparation method thereof, belonging to the technical field of aquaculture medicine. Background technique [0002] Bacillus mycoides is an emerging opportunistic pathogen with spores, which is pathogenic to aquatic animals such as snakehead, Chinese soft-shelled turtle, and California perch. [0003] However, the control drugs for this bacteria are extremely scarce at present, and none of the existing literature has reported it. Therefore, it is very necessary to develop effective agents against pathogenic Bacillus mycoides in order to effectively control the pathogenic Bacillus mycoides in the aquaculture environment and reduce the incidence of aquatic animals caused by it. [0004] The compound preparation of Chinese and Western medicine is a kind of emerging medicine, is the compound preparation after Chinese medicine and Western medicine are carried out d...

Claims

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Application Information

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IPC IPC(8): A61K36/815A61P31/04A61K31/14A61K31/7036
CPCA61K31/14A61K31/7036A61K36/736A61K36/815A61P31/04A61K2300/00
Inventor 曹海鹏郭成陈思佳叶伟东顾颖
Owner SHANGHAI OCEAN UNIV