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Self-expanding drug sustained-release stent and taking and placing device thereof

A self-expanding, sustained-release technology, applied in stents, drug devices, medical science, etc., can solve the problems of long-term blockage of sinus orifices, slow drug treatment, and damage, shorten the treatment cycle, ensure the treatment effect, and prolong the treatment. effect of cycles

Pending Publication Date: 2020-01-14
乐畅医疗器械(上海)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The above-mentioned prior art scheme has the following defects: the price of FESS operation is high, and the recurrence rate is high. The recurrence rate after surgery to remove nasal polyps is 30%-50%, and each patient needs to perform at least 1.5-4 operations on average , because the support strength of the drug sustained-release stent itself is low, it is often necessary to remove anatomical structures such as turbinates, nasal septum, nasal mucosa, and nasal polyps during surgery. This type of resection and reconstruction will destroy the natural filtration and reconstruction provided by these structures. Humidification function, leading to dryness, bleeding, scabbing, increased risk of infection, and may cause olfactory changes including hyposmia, dysosmia, parasmia, and anosmia
[0006] If conservative treatment is carried out by direct nasal administration, due to the blockage of swollen nasal polyps and other intranasal tissues in the diseased sinuses, the drug sustained-release stent is not rigid enough to directly squeeze and support nasal polyps and expand the sinus opening. Directly and accurately reach the lesion site, resulting in extremely slow drug treatment, nasal polyps cannot be cured in time, and the sinus ostium will still be blocked for a long time, making the treatment cycle too long

Method used

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  • Self-expanding drug sustained-release stent and taking and placing device thereof
  • Self-expanding drug sustained-release stent and taking and placing device thereof
  • Self-expanding drug sustained-release stent and taking and placing device thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0054] See attached figure 1 , a self-expanding drug slow-release stent 1, including a self-expanding stent composition, the self-expanding stent composition includes a slow-release stent 1, a self-expanding component 2, and a connector 3; the slow-release stent 1 includes a slow-release microtube 11, the The sustained-release microtubes 11 are cross-connected to form a sustained-release stent 1 with an annular network structure, and symptomatic drugs are arranged on the sustained-release stent 1 .

[0055] Symptomatic drugs include one or more of antibacterial drugs, anti-inflammatory drugs, anticancer drugs, and hemostatic drugs. Symptomatic drugs can contact and release nasal wall and polyps, thereby inhibiting polyp re-growth and reducing nasal inflammation; self-expanding The stent composition can be made of materials such as stainless steel, cobalt-chromium alloy, nickel-titanium alloy, magnesium alloy, etc., can also be formed of degradable metals such as magnesium, pur...

Embodiment 2

[0061] See attached Figure 7 , Figure 8 , a self-expanding drug slow-release stent 1, the difference from Embodiment 1 is that the positioning rod 21 is also provided with a second sliding piece 213 and a third sliding piece 214, the second sliding piece Part 213 and the third sliding part 214 are located between the first sliding part 212 and the fixed end 211 in sequence; the expansion struts 23 are arranged in three groups along the axial direction of the positioning rod 21, according to the distance from the fixed end 211 The closest order is the first expansion part 24 , the second expansion part 25 and the third expansion part 26 .

[0062] The first expansion part 24, the second expansion part 25, and the third expansion part 26 respectively include four expansion struts 23 uniformly arranged along the circumferential direction of the positioning rod 21; the two ends of each expansion strut 23 in the first expansion part 24 They are respectively connected with the f...

Embodiment 3

[0067] See attached Figure 10 , a self-expanding drug sustained-release stent 1, the difference from Example 2 is that the drug sustained-release layer 4 is arranged on the outer peripheral side of the above-mentioned sustained-release stent 1, the drug sustained-release layer 4 has elasticity, and the drug sustained-release layer 4 Symptomatic drugs are evenly arranged, and the symptomatic drugs include one or more of antibacterial drugs, anti-inflammatory drugs, anticancer drugs, and hemostatic drugs.

[0068] During actual use, the trumpet-shaped self-expanding stent composition supports the extrusion of nasal polyps on the affected part of the patient, and the drug slow-release layer 4 accurately covers the lesion, and forms a specific shape at the specific shape of the lesion , so that the symptomatic drugs can be accurately and evenly distributed to every part of the lesion.

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Abstract

The invention relates to a self-expanding drug sustained-release stent and a taking and placing device thereof, which relates to the technical field of ear-nose-throat medical instruments. The self-expanding drug sustained-release stent comprises a sustained-release stent body, a self-expanding assembly, a connecting piece and symptomatic drugs. The self-expanding assembly comprises a positioningrod, a first elastic piece, a first sliding piece, a second sliding piece, a third sliding piece and a plurality of expanding supporting strips, nasal polyp at the diseased position of a patient can be expanded conveniently, further expanding is generating along with nasal polyp atrophy due to the weakened illness state of the patient, the precise medicine application is achieved, the treatment period is shortened, and the treatment effect is fully guaranteed. The taking and placing device for the self-expanding drug sustained-release stent comprises a first placing sleeve, a second placing sleeve and a clamping piece, the operation is easy and convenient, a nasal sinus stent can be conveniently taken and placed, the operation convenience of doctors is greatly improved, and surgical risksand postoperative sequelae risks are avoided.

Description

technical field [0001] The invention relates to the technical field of ear, nose and throat medical devices, in particular to a self-expanding drug slow-release stent and a pick-and-place device thereof. Background technique [0002] The sinuses, also known as paranasal sinuses and paranasal sinuses, are multiple air-filled bony cavities around the nasal cavity. The mucous membranes of the sinuses are connected with the nasal mucous membranes, so the inflammation of the nasal mucous membranes often spreads to the sinus mucous membranes, causing sinusitis. At present, it is believed that the pathogenesis of sinusitis is mainly due to the infection of the sinuses due to the obstruction of the sinus opening caused by various reasons. Among them, nasal polyps are an important reason for the obstruction of the opening of the sinuses, and the inflammatory stimulation of the sinuses in turn promotes the growth of nasal polyps. Form a vicious circle. [0003] The current treatment...

Claims

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Application Information

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IPC IPC(8): A61F2/82A61M31/00A61F2/966A61F2/97
CPCA61F2/82A61F2/966A61F2/97A61F2250/0067A61M31/002A61M2210/0618A61M2210/005
Inventor 余洪猛许伦王丽杨海
Owner 乐畅医疗器械(上海)有限公司