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Medical collagen wound repair film

A technology of wound repair and collagen film, which is applied in the field of medical glue original surface repair film, can solve the problems of lower body temperature on the wound surface, easy shedding of antibacterial agents, wound infection, etc., achieve good force buffering effect, improve antibacterial performance, and improve mechanical intensity effect

Active Publication Date: 2020-02-07
HENAN YADU IND
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] The skin provides protection for the human body. Once the skin is injured, it will have a great impact on body functions; therefore, after the skin is injured, it is necessary to protect the wound in time to avoid infection of the wound; currently commonly used wound repair supplies include gauze, gel Dressings, Band-Aids, sponge dressings, etc., and these wound repair products are applied to the wound surface to protect the wound, stop bleeding, and promote wound healing, and the wound repair materials applied to the wound surface will not There is a certain degree of oppression, which causes the temperature on the surface of the wound to drop, causing discomfort to the patient. The reason for this phenomenon is that the wound is covered and affects the blood circulation on the surface of the wound, which is not conducive to wound healing. Therefore, the wound repair film has Promoting wound blood circulation plays an important role in promoting wound repair and shortening the wound healing cycle; in addition, in real life, wounds will inevitably be damaged by external forces, and when the wound is touched by external forces, it will cause great pain to the patient Therefore, it is of positive significance to endow the wound dressing with a certain buffering effect, thereby reducing the damage of external force to the wound surface
[0003] At present, the wound repair film only has a protective effect on the wound, and for severe wounds, the wound healing period is longer, which inevitably causes wound infection. Therefore, improving the antibacterial performance of the repair film plays an important role in wound repair. At present, the antibacterial agent is usually adsorbed on the repair film in the form of physical adsorption. On the one hand, the antibacterial agent is easy to fall off and affects the antibacterial performance of the wound repair film; The problem of side effects

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] A medical collagen original repair film, the medical collagen original repair film has a three-layer structure composed of graphene oxide / collagen film and composite gel microspheres, the upper and lower layers of the wound repair film are oxidized Graphene / collagen film, described middle layer is composite gel microsphere; Described graphene oxide / collagen film is to be raw material with graphene oxide, fish scale collagen, garlic extract, and polylysine is The cross-linking agent is prepared; the composite gel microspheres are prepared from the following raw materials in parts by weight: 4 parts of sodium alginate, 4 parts of polyethylene glycol, 2 parts of polyethyleneimine, 0.2 parts of liquid silicone rubber 0.4 part of zeolite, 0.1 part of medical stone, 0.05 part of vermiculite, 0.5 part of aloe extract, 0.4 part of comfrey root extract and 0.2 part of bletilla striata extract;

[0038] The preparation method of described medical collagen original facial repair f...

Embodiment 2

[0051] A medical collagen original repair film, the medical collagen original repair film has a three-layer structure composed of graphene oxide / collagen film and composite gel microspheres, the upper and lower layers of the wound repair film are oxidized Graphene / collagen film, described middle layer is composite gel microsphere; Described graphene oxide / collagen film is to be raw material with graphene oxide, fish scale collagen, garlic extract, and polylysine is The crosslinking agent is prepared; the composite gel microspheres are prepared from the following raw materials in parts by weight: 5 parts of sodium alginate, 5 parts of polyethylene glycol, 2.5 parts of polyethyleneimine, and 0.25 parts of liquid silicone rubber 0.5 part of zeolite, 0.15 part of medical stone, 0.075 part of vermiculite, 0.75 part of aloe extract, 0.6 part of comfrey root extract and 0.25 part of bletilla striata extract;

[0052] The preparation method of described medical collagen original facia...

Embodiment 3

[0065] A medical collagen original repair film, the medical collagen original repair film has a three-layer structure composed of graphene oxide / collagen film and composite gel microspheres, the upper and lower layers of the wound repair film are oxidized Graphene / collagen film, described middle layer is composite gel microsphere; Described graphene oxide / collagen film is to be raw material with graphene oxide, fish scale collagen, garlic extract, and polylysine is The cross-linking agent is prepared; the composite gel microspheres are prepared from the following raw materials in parts by weight: 6 parts of sodium alginate, 6 parts of polyethylene glycol, 3 parts of polyethyleneimine, and 0.3 parts of liquid silicone rubber 0.6 part of zeolite, 0.2 part of medical stone, 0.1 part of vermiculite, 1 part of aloe extract, 0.8 part of comfrey root extract and 0.3 part of Bletilla striata extract;

[0066] The preparation method of described medical collagen original facial repair ...

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Abstract

The invention discloses a medical collagen wound repair membrane, which is of a three-layer structure composed of a graphene oxide / collagen membrane and composite gel microspheres, the upper layer andthe lower layer are both the graphene oxide / collagen membrane, and the middle layer is the composite gel microspheres; the graphene oxide / collagen membrane is prepared by taking graphene oxide, fishscale collagen and a garlic extract as raw materials and polylysine as a cross-linking agent. The composite gel microspheres are loaded on the graphene oxide / collagen membrane in an electrostatic spraying manner. The collagen wound repair film has good mechanical strength and good elasticity; the collagen wound repair film is used for wound repair, has good hemostatic and antibacterial properties,has the effect of radiating infrared rays to promote blood circulation on the surface of a wound so as to promote wound healing and shorten the wound healing period, and can also avoid the problem that the wound healing speed is reduced due to secondary wound injury caused by the fact that the wound is subjected to external force again.

Description

technical field [0001] The invention relates to the field of medical supplies, in particular to a medical glue original surface repair film. Background technique [0002] The skin provides protection for the human body. Once the skin is injured, it will have a great impact on body functions; therefore, after the skin is injured, it is necessary to protect the wound in time to avoid infection of the wound; currently commonly used wound repair supplies include gauze, gel Dressings, Band-Aids, sponge dressings, etc., and these wound repair products are applied to the wound surface to protect the wound, stop bleeding, and promote wound healing, and the wound repair materials applied to the wound surface will not There is a certain degree of oppression, which causes the temperature on the surface of the wound to drop, causing discomfort to the patient. The reason for this phenomenon is that the wound is covered and affects the blood circulation on the surface of the wound, which ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/28A61L15/26A61L15/24A61L15/18A61L15/40A61L15/32
CPCA61L15/28A61L15/26A61L15/24A61L15/18A61L15/40A61L15/325A61L2300/30A61L2300/418A61L2300/412A61L2300/45C08L5/04C08L71/02C08L39/02
Inventor 张正男段书霞韩涵付迎坤孙海鹏石沛龙崔彬彬邵蕊娜韩修恒田崇周静郝明严子跃佘开江姬鹏远王喜卫
Owner HENAN YADU IND
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