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Ultrasonic fine efficient thrombolysis system assisted by low-intensity focused vortex sound field

A focused ultrasound, low-intensity technology, applied in medical science, surgery, etc., can solve the problem of large size of thrombus fragments, achieve good flexibility and safety, reduce size, and enhance the effect of interaction

Active Publication Date: 2020-02-18
XI AN JIAOTONG UNIV
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  • Abstract
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  • Claims
  • Application Information

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Problems solved by technology

[0006] In summary, the existing high-intensity focused ultrasound thrombolysis technology has the disadvantage of excessive size of thrombus fragments, and the ultrasonic fine thrombolysis technology based on the standing wave field also has certain limitations and hidden dangers. There is a need to improve the efficiency of thrombolysis

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  • Ultrasonic fine efficient thrombolysis system assisted by low-intensity focused vortex sound field
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  • Ultrasonic fine efficient thrombolysis system assisted by low-intensity focused vortex sound field

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Embodiment Construction

[0034] The present invention will be further described in detail below in conjunction with the accompanying drawings and embodiments.

[0035] see figure 1 , the low-intensity focused vortex sound field-assisted ultrasonic fine and efficient thrombolysis method proposed by the present invention uses high-intensity focused ultrasonic sound field to dissolve thrombus, and uses low-intensity focused ultrasonic vortex sound field to gather thrombus fragments and cavitation microbubbles , and finally realized the fine and efficient ultrasonic dissolution of thrombus in the vascular mimic, which specifically includes the following steps:

[0036] Step 1. Install the multi-element low-intensity focused ultrasound vortex transducer, single-element high-intensity focused ultrasound transducer, transparent blood vessel phantom and high-speed microscopic camera, and precisely adjust the relative spatial positions among the four. The specific spatial locations are arranged in the followi...

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Abstract

The invention discloses an ultrasonic fine efficient thrombolysis system assisted by a low-intensity focused vortex sound field. The ultrasonic fine efficient thrombolysis system comprises a high-intensity focused ultrasonic transducer and a low-intensity focused ultrasonic vortex transducer of which the sound field focused region is mutually overlapped with that of the ultrasonic transducer. Compared with a conventional high-intensity focused ultrasonic thrombolysis system, the ultrasonic fine efficient thrombolysis system disclosed by the invention is assisted by the low-intensity focused vortex sound field, and cavitation microvesicles and thrombus fragments in the thrombolysis process are acquired and focused in the sound field focused region to strengthen interaction between the cavitation microvesicles, thrombosis and fragments thereof, so that the size of the thrombosis fragments is reduced, the thrombolysis efficiency can be improved, and a safer and more efficient ultrasonic thrombolysis manner is provided. The low-intensity focused ultrasonic vortex transducer which can be located on one side of a treatment region can produce needed momentum traps, and a sound manipulation region is only limited in the vortex sound field focused region, so that compared with a high-intensity focused ultrasonic standing wave thrombolysis technique, the ultrasonic fine efficient thrombolysis system disclosed by the invention has better flexibility and safety, and is more suitable for ultrasonic thrombolysis treatment under the condition of living bodies.

Description

technical field [0001] The invention belongs to the field of ultrasound physics, control and treatment, and in particular relates to a low-intensity focused vortex sound field-assisted ultrasound fine and high-efficiency thrombolysis system. Background technique [0002] According to the World Health Organization report in 2010, the death of cardiovascular disease accounts for the first cause of death in the world, and the occurrence of many heart, brain and peripheral vascular diseases is related to the formation of thrombus, so safe and efficient thrombolysis is of great significance. At present, the clinical treatment of thrombosis mainly includes drug thrombolysis, intravascular catheter interventional thrombectomy, or a combination of the two. The introduction has disadvantages such as invasiveness, susceptibility to infection, and only applicable to large-sized blood vessels (diameter greater than 2mm). [0003] Studies have shown that the introduction of low-intensit...

Claims

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Application Information

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IPC IPC(8): A61B17/22
CPCA61B17/22004A61B2017/22007A61B2017/22028
Inventor 万明习郭世放郭叙言王昕牙振
Owner XI AN JIAOTONG UNIV
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