Preparation method of self-supporting Co-MOF/TM nanosheet array, electrochemical biosensor and application

A nanosheet array and biosensor technology, applied in the field of new nanomaterials, can solve the problems of low conductivity and catalytic activity, and achieve the effects of fast electron transfer rate, high selectivity and excellent electrochemical performance.

Inactive Publication Date: 2020-02-28
QUFU NORMAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although MOFs materials have low cost and excellent sensing performance, their electrical conductivity and catalytic activity are low, and there are still many problems in electrochemical sensing.

Method used

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  • Preparation method of self-supporting Co-MOF/TM nanosheet array, electrochemical biosensor and application
  • Preparation method of self-supporting Co-MOF/TM nanosheet array, electrochemical biosensor and application
  • Preparation method of self-supporting Co-MOF/TM nanosheet array, electrochemical biosensor and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] 0.238 g CoCl 2 • 6 H 2 O and 0.166 g TPA were dissolved in 33 ml DMF and stirred for 10 min. Then add 2.5 ml ethanol and 2.5 ml deionized water and stir for 25 minutes. The above mixture was transferred to a 50 ml autoclave and a clean titanium mesh (TM) was placed in it. The reaction was carried out at 125°C for 12 hours. Finally, the obtained sample was naturally cooled, washed three times with deionized water and ethanol, and dried in air at 60 °C for 6 h to obtain Co-MOF / TM.

Embodiment 2

[0032] 0.25 g CoCl 2 • 6 H 2 O and 0.18 g TPA were dissolved in 40 ml DMF and stirred for 10 min. Add 3 ml of ethanol and 3 ml of deionized water and stir for 30 minutes. The above mixture was transferred to a 50 ml autoclave and a clean titanium mesh (TM) was placed in it. The reaction was carried out at 125°C for 12 hours. Finally, the obtained sample was naturally cooled, washed three times with deionized water and ethanol, and dried in air at 60 °C for 6 h to obtain the Co-MOF / TM

Embodiment 3

[0034] 0.20 g CoCl 2 • 6 H 2 O and 0.15 g TPA were dissolved in 30 ml DMF and stirred for 10 min. Add 2 ml of ethanol and 2 ml of deionized water and stir for 20 minutes. The above mixture was transferred to a 50 ml autoclave and a clean titanium mesh (TM) was placed in it. The reaction was carried out at 125°C for 12 hours. Finally, the obtained sample was naturally cooled, washed three times with deionized water and ethanol, and dried in air at 60 °C for 6 h to obtain the Co-MOF / TM

[0035] electrochemical biosensor

[0036] The electrochemical biosensor of the present invention comprises a working electrode connected to an electrochemical workstation, a reference electrode (Ag|AgCl|Cl - ), the counter electrode (graphite electrode), the working electrode is a titanium mesh (TM), and the working electrode is a titanium mesh (TM) decorated with the Co-MOF / TM nanosheet array prepared in the example. Ultrasonic cleaning in pure water for 15 min, the area of ​​the TM electro...

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Abstract

The invention belongs to the technical field of new nano materials, and particularly relates to a preparation method of a self-supporting Co-MOF / TM nanosheet array, an electrochemical biosensor and anapplication. The preparation method comprises the following steps: dissolving CoCl2. 6H2O and TPA in DMF, perfomring stirring, adding ethanol and ultrapure water, and performing continuous stirring to obtain a mixed solution; putting the titanium mesh into the mixed solution for hydrothermal reaction, and cooling, washing and drying an obtained sample to obtain the Co-MOF / TM nanosheet array. Thenanosheet array prepared by the invention has the advantages of high electron transfer rate and high conductivity, and the prepared electrochemical sensor has the advantages of low detection limit, good stability and excellent electrochemical performance. Meanwhile, the preparation method is simple, and materials are easy to obtain.

Description

technical field [0001] The invention belongs to the technical field of new nanometer materials, and in particular relates to a preparation method of a self-supporting Co-MOF / TM nanosheet array, an electrochemical biosensor and its application. Background technique [0002] hydrogen peroxide (H 2 o 2 ) is an important biomarker that plays a key role in physiological processes and has a positive effect on H 2 o 2 The analysis and detection of them are of great significance in the fields of clinical, pharmaceutical, industrial and environmental analysis. In biological systems, H 2 o 2 The concentration of H is considered to be an important physiological parameter, and high levels of H 2 o 2 Harmful to cells and can cause various diseases. In addition, H 2 o 2 It is a by-product of a series of biological processes, and it plays a vital role in vascular reconstruction, control of life activities, cell proliferation and apoptosis. Therefore, monitoring the H release fro...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N27/327
CPCG01N27/327
Inventor 渠凤丽张新悦李钦孔荣梅
Owner QUFU NORMAL UNIV
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