Bactericidal composition containing indole hydrazide

A technology of indole hydrazide and composition, which is applied in the field of pesticide composition, can solve the problems of undiscovered therapeutic effect, high price of fungicides, increased research and development efforts, etc., to achieve reduced usage, significant preventive and therapeutic effects, and alleviate The effect of environmental pollution

Inactive Publication Date: 2020-04-10
JINGBO AGROCHEM TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the therapeutic effect of indole hydrazide on plant fungal diseases has not yet been reported.
In addition, the single use of pesticides will bring resistance risks, and the combination of pesticides is an effective way to solve the problem of resistance
The development of new fungicides is expensive and has a long cycle. In contrast, the development and research of high-efficiency, low-toxicity, and low-residue compounding and mixing have low investment and short development cycles, and have attracted attention at home and abroad, and they have increased research and development. Strength
The combination of hymexazol and indole hydrazide has not been reported

Method used

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  • Bactericidal composition containing indole hydrazide
  • Bactericidal composition containing indole hydrazide
  • Bactericidal composition containing indole hydrazide

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Example 1: 6% indole hydrazide hymexazol aqueous solution

[0028] Raw materials are proportioned by weight: 5% hymexazol, 1% indole hydrazide, 20% Tween 80, 20% potassium dihydrogen phosphate, and 100% water. Preparation method: It can be prepared according to the conventional water preparation production method.

[0029] The drug efficacy comparison test was carried out between the sample of Example 1 and the control drug 5% indole hydrazide aqueous suspension (made in the laboratory) and 15% hymexazol aqueous solution (outsourced). Control objects: Chinese cabbage root rot, tomato gray mold. The control effect is shown in the table below:

[0030]

[0031] The average temperature during medication is 21-25°C, and the weather is mostly sunny. The data show that the dosage of the compound preparation is about 10% lower than that of the two single dosages after mixing 1:1, but the anti-inflammatory effect is lower than that of the two single dosages. The control e...

Embodiment 2

[0032] Example 2: 20% indole hydrazide hymexazol emulsifiable concentrate

[0033] The proportion of raw materials by weight: 10% indole hydrazide, 10% hymexazol, 8% agricultural milk 500#, 6% agricultural milk 400#, 7% agricultural milk 600#, the rest is supplemented with heavy benzene. Preparation method: It can be prepared according to the conventional production method of emulsifiable oil.

[0034] The drug efficacy comparison test was carried out between the sample of Example 2 and the control drug 5% indole hydrazide aqueous suspension (made in the laboratory) and 15% hymexazol aqueous solution (outsourced). Control object: Cucumber downy mildew, the control effect is shown in the table below:

[0035]

[0036]

[0037] The average temperature is 21-25°C when using the medicine, and the weather is mainly sunny. The data show that the dosage of the compound preparation is about 10% lower than that of the two single dosages after mixing 1:1, but the antibacterial ef...

Embodiment 3

[0038] Example 3: 36% indole hydrazide · hymexazol large granules

[0039] Raw materials are proportioned by weight: 30% of indole hydrazide, 6% of hymexazol, 5% of sodium carboxymethyl starch, 50% of washed sand, 3% of rhodamine, and the rest is supplemented with kaolin. It is prepared according to the conventional production method of spreading granules.

[0040] Embodiment 3 sample and contrast agent 2% indole hydrazide large granule (laboratory self-made) and 30% hymexazol large granule (laboratory self-made) carry out drug efficacy comparative test, control object: rice sheath blight, control The effect is shown in the table below:

[0041]

[0042] The average temperature is 21-25°C when using the medicine, and the weather is mainly sunny. The data show that: compared with the single agent, the dosage of the compound preparation is more than 10% lower than that of the two single agents after 1:1 mixing, but the anti-inflammatory effect is lower than that of the two s...

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PUM

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Abstract

The invention belongs to the field of pesticide compositions, and particularly relates to a bactericidal composition containing indole hydrazide. The effective components of the bactericidal composition comprise indole hydrazide and hymexazol in a weight ratio of 50: 1 to 1: 50. The bactericidal composition can also be processed into a pesticide preparation. The bactericidal composition comprisesadjuvants and effective components, wherein the mass percentage content of indole hydrazide and hymexazol in the composition is 1%-80%, with the balance being the pesticide effective components. The pesticide composition has a special effect of preventing and treating fungal downy mildew and fusarium wilt of cucumber, and can also be used for preventing and treating plant diseases caused by infection of other fungi, e.g., Chinese cabbage root rot, cotton damping-off, tomato gray mold, pepper fungal anthracnose, rice sheath blight disease, wheat scab, green Chinese onion purple spot, eggplant sclerotinia sclerotiorum, watermelon gummy stem blight and tomato late blight. The invention has the characteristics of high efficiency, low toxicity and low residue, and is especially beneficial for the production of green food.

Description

technical field [0001] The invention belongs to the field of pesticide compositions, in particular to a fungicidal composition containing indole hydrazide. Background technique [0002] Indole hydrazide is a compound containing an acylhydrazone structure developed by Nankai University, which has good biological activity against fungal diseases of crops. It is easily absorbed by plants, easily degraded in the environment, and has good environmental compatibility. [0003] The chemical name is: (1S,3S)-N'-(cyclohexylmethylene)-1-methyl-2,3,4,9-tetrahydropyrido[3,4-b]indole-3- Formic hydrazide (abbreviated as indole hydrazide in the present invention). [0004] [0005] Hymexazol: The chemical name is: 3-hydroxy-5-methylisoxazole, which belongs to oxazole fungicides. Its mechanism of action inhibits mitochondrial respiration of pathogenic bacteria, but it is different from β-methoxyacrylate fungicides. The agent is a broad-spectrum fungicide, which has a good control effe...

Claims

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Application Information

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IPC IPC(8): A01N43/90A01N43/80A01P3/00
CPCA01N43/80A01N43/90
Inventor 冀琳琳邓晓杰王辉王成张方贺许兴志刘坤张宗英赵显冰赵艳龙
Owner JINGBO AGROCHEM TECH CO LTD
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