Pharmaceutical compositions of ramelteon and methods of use thereof

A technology of ramelteon and composition, applied in the field of ramelteon pharmaceutical composition for the treatment of insomnia and jet lag syndrome
CN110996938AInactive Publication Date: 2020-04-10MAXINASE LIFE SCI LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
MAXINASE LIFE SCI LTD
Publication Date
2020-04-10
Estimated Expiration
Not applicable · inactive patent

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Abstract

Pharmaceutical compositions of ramelteon for use in the treatment of insomnia or jet lag by transmucosal administration. More specifically, the pharmaceutical composition is formulated into nasal spray or nasal drop for intranasal administration, or formulated into sublingual spray for sublingual administration, or formulated into a solid dosage for sublingual administration.
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Description

technical field

[0001] The present invention relates to a pharmaceutical composition of ramelteon and a method of use thereof. More specifically, the present invention relates to pharmaceutical compositions of ramelteon for the treatment of insomnia and jet lag by transmucosal administration. The present invention achieves a faster onset of pharmacological action by delivering low doses of ramelteon via intranasal or sublingual routes compared to conventional oral tablet administration. Background technique

[0002] About 30% to 40% of the population suffers from mild to severe insomnia. Insomnia can cause impairments in physical and mental health, such as fatigue and reduced alertness, irritability and inability to concentrate, increasing the risk of accidents and reducing productivity. All of these symptoms have a negative impact on quality of life. Appropriate treatment of insomnia includes lifestyle changes, sleep hygiene, and pharmacological intervention with sedativ...

Claims

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