35results about How to "High suppression efficiency" patented technology

The invention provides a siRNA gene inhibition efficiency screening model construction and training method, a siRNA gene inhibition efficiency screening device and a siRNA gene inhibition efficiency screening method. The construction and training method comprises the following steps: acquiring first sequence information of target mRNA and second sequence information of siRNA; obtaining first space image information of the target mRNA and second space image information of the siRNA; constructing a siRNA gene inhibition efficiency screening model, and training a first neural network model by using the first sequence information and the second sequence information to extract sequence features; training a second neural network model by using the first spatial image information and the second spatial image information to extract spatial structure features; and fusing the sequence features and the spatial structure features, and training a third neural network model by using the fused features. Therefore, the accuracy of screening the siRNA with the inhibition efficiency on the target gene can be improved.

The invention relates to the technical field of motors, in particular to a vehicle motor torque ripple suppression method and device.The method comprises the steps that the current torque, the current rotating speed and the current electrical angle of at least one motor of a vehicle are obtained, a relation table of the torque, the rotating speed and the electrical angle and iq compensation values is inquired, and a target iq compensation value for suppressing torque ripple is obtained, wherein the relation table is calculated by a pre-trained neural network model, and the output of the at least one motor is controlled according to the target iq compensation value, so that the actual rotating speed output by the at least one motor is consistent with the target rotating speed. According to the embodiment of the invention, the iq compensation value relation table of the vehicle motor can be obtained based on the neural network model, and the relation table is inquired according to the current torque, the current rotating speed and the current electrical angle so as to obtain the iq compensation value capable of suppressing the torque ripple, so that comprehensive suppression of the torque ripple is realized, the suppression precision of the vehicle motor to the torque ripple is improved, and the suppression efficiency of the vehicle motor is improved. And stability and practicability are realized.

The invention provides a plasmodiophora brassicae effector Pb78, and the nucleotide sequence of the plasmodiophora brassicae effector Pb78 is shown The invention also provides an application of host-induced silencing of the plasmodiophora brassicae effector Pb78 in prevention and treatment of plasmodiophora brassicae infection, and also provides a plasmodiophora brassicae prevention and treatment liquid and a preparation method of the plasmodiophora brassicae prevention and treatment liquid. The invention verifies that host-induced plasmodiophora brassicae effector Pb78 silencing can effectively inhibit plasmodiophora brassicae infection and symptom formation of cruciferae plants. The preparation and the treatment method disclosed by the invention are suitable for various cruciferae crops and vegetables which can be infected by plasmodiophora brassicae, and are wider in applicability; the inhibition efficiency on clubroot is higher than that of medicament treatment, and the compound has the advantage of no pesticide residue and is high in safety; due to the adoption of a seed treatment mode, the method is particularly suitable for preventing and treating clubroot susceptible seedlings.

The present invention provides an electromagnetic interference suppression method and system for a chip, which relates to the technical field of intelligent chips, and comprises the following steps: obtaining layout data of a target chip, extracting structural parameters and device parameters based on the layout data through an image segmentation algorithm, and constructing a multi-physical field coupling simulation model; determining the optimal excitation source corresponding to the target chip through a machine learning algorithm, adopting a time-domain finite element method, calculating and obtaining transient multi-physical field distribution through an adaptive time step control strategy, extracting multi-scale distribution features in the time-frequency domain, constructing a spectrum fingerprint library of electromagnetic interference using a deep convolutional neural network, and generating an electromagnetic interference identification result; determining the optimal suppression circuit topology based on the electromagnetic interference identification result through a suppression topology search algorithm, determining the optimal suppression device parameters through a multi-objective optimization algorithm combined with electromagnetic compatibility index constraints, and generating an electromagnetic interference suppression strategy.

The invention relates to a gas dust explosion prevention and control targeted explosion suppressant regulation and control method based on machine learning, and belongs to the technical field of explosion prevention and control and material modification. According to the method, the inhibition effect of the explosion suppressant in a composite explosion environment is analyzed through a machine learning model, and targeted optimization is performed on the components, concentration and physical structure of the explosion suppressant based on experimental data and characteristic characterization. The method comprises the following specific steps: screening explosion suppressant components through literature investigation; carrying out modified compounding on the explosion suppressant and collecting explosion characteristic data; carrying out feature importance analysis by utilizing an XGBoost model, and identifying key factors influencing the explosion suppression effect; and optimizing the formula of the explosion suppressant according to a model analysis result, and verifying the effect through experiments. According to the method, the inhibition efficiency and adaptability of the explosion suppressant under the compound explosion condition are greatly improved, data-driven intelligent design is achieved, and the method is suitable for various industrial explosion prevention and control scenes.

The present invention discloses a method, device and storage medium for suppressing overvoltage of SLCC converter valves, the method comprising: obtaining a first extreme working condition by traversing overvoltage fault scenarios through simulation, and optimizing the bridge arm reactor parameters according to the first extreme working condition to obtain a first scheme for suppressing overvoltage; when the first scheme cannot effectively suppress overvoltage, simulation is performed based on the first extreme working condition and the optimized bridge arm reactor parameters, and the valve-controlled unbalanced protection action constant is optimized to obtain a second scheme for further suppressing overvoltage; when the second scheme cannot effectively suppress overvoltage, simulation is performed based on the optimized bridge arm reactor parameters and the valve-controlled unbalanced protection action constant to obtain a second extreme working condition; based on the second extreme working condition, combined with engineering requirements, the converter valve assembly is optimized until a scheme that can effectively suppress overvoltage is obtained. The present invention realizes effective suppression of overvoltage of SLCC converter valves through the joint design of primary and secondary systems.

The invention relates to the technical field of lithium battery thermal runaway suppression, and discloses a simulation system for lithium battery thermal runaway suppression by multi-particle-size water mist, which comprises a data acquisition module for lithium battery temperature acquisition, the temperature monitoring module is used for monitoring and predicting the temperature of the lithium battery and correcting the output of the temperature monitoring unit to monitor and predict the temperature of the lithium battery; the water mist control module is used for controlling the spraying type of particle size water mist and controlling the spraying momentum of fog drops; the suppression analysis module is used for performing suppression result analysis on the thermal runaway of the lithium battery; the feedback module is used for feeding back battery thermal runaway temperature response data and a particle size water mist cooling effect; according to the invention, higher monitoring precision can be ensured, the diameter of water mist and the momentum of fog drops are allowed to be adjusted according to different conditions, and a targeted inhibition effect is realized.

This utility model relates to the field of tea brick production and discloses a hydraulically driven automatic tea brick pressing device, including a pressing table. Support legs are installed on both sides of the bottom of the pressing table. An adjusting platform is movably connected to the top of the pressing table. Four sets of pressing seats are fixedly installed on the top of the adjusting platform. Each pressing seat has a pressing chamber inside, and a pre-reserved groove is provided below the pressing chamber. A second hydraulic cylinder is installed inside the pre-reserved groove, and a top plate is installed at the output end of the second hydraulic cylinder. During processing, tea leaves enter the guide pipe through the connecting pipe and then fall into the pressing chamber of the pressing seat. The first hydraulic cylinder then pushes the pressing plate downwards to press the tea leaves into tea bricks. After pressing, the adjusting platform rotates 90 degrees to move the pressing seats away from below the guide pipe to discharge the tea. Simultaneously, the other two empty pressing seats repeat the pressing operation, solving the problem of low pressing efficiency.

This utility model discloses a liquid baffle with foam suppression function for electrolytic cells, including a liquid baffle body. Vertical plates are fixedly connected to the top four sides of the liquid baffle body. A drive motor is bolted to the outer side of each vertical plate. A threaded rod is fixedly connected to the output end of the drive motor, and a movable plate is threadedly connected to the surface of the threaded rod. This utility model utilizes the synergistic action of a stirring motor, a rotating disc, a crushing rod, a vibrating motor, a vibrating rod, crushing blocks, and spikes to treat foam from multiple aspects, including stirring, crushing, and vibrating. Compared to traditional liquid baffles, it improves foam suppression efficiency, effectively maintains stable liquid levels in the electrolytic cell, and reduces the adverse effects of foam overflow. The lifting structure composed of the drive motor, threaded rod, and movable plate can flexibly adjust the position of the crushing components according to the height and distribution of foam in the electrolytic cell, ensuring good foam suppression effects under different operating conditions.

This invention discloses a control method and device for a solar-fossil fuel complementary energy storage power generation system. The method includes the following steps: in response to a start command, acquiring the transfer parameters of the controlled object; acquiring a first input value and a first output value of the controlled object; inputting the first input value and the first output value into an extended state observer to obtain observation parameters; acquiring a first preset output value of the controlled object; calculating a second input value based on the first preset output value, observation parameters, transfer parameters, preset tuning coefficients, and a preset error feedback control model; updating the first input value based on the second input value; outputting the updated first input value to the controlled object, acquiring the updated first output value, and returning to execute the third step. The control method and device disclosed in this invention can improve the efficiency of disturbance suppression, thereby reducing the fluctuation range of the controlled object's output and improving stability.

The invention discloses a working face dust removal, spraying and fresh air system for a coal mine, and belongs to the technical field of coal mine underground environment governance and occupational health safety. The system comprises a track hoisting and moving device, a wet-type vortex dust removal fan, a spraying and dust falling device, a fresh air device and an automatic control system. The structural frame is hung on the moving trolley through the hanging chain and is driven by the driving main machine to move dynamically along the track. The dust removal fan adopts the combination of a radial mixing type impeller and a dewatering vortex wheel, so that powerful dust collection and dry and comfortable exhaust are realized; the spraying device realizes intelligent avoiding and spraying stopping through a personnel proximity sensor; the fresh air device is of a double-channel structure, and positive-pressure clean fresh air is provided for the breathing area through four-stage deep purification. The problems that traditional equipment is installed and fixed, functions are split, people are prone to getting wet, and breathing guarantee is lacked are solved, integrated cooperation of full-working-face dynamic cruise control, precise dust suppression and medical-grade fresh air supply is achieved, and the safety and comfort of underground operation are remarkably improved.

The utility model relates to the technical field of rock wool insulation board processing, in particular to a rock wool insulation board insertion port pressing tool which comprises a processing box, a first pressing mechanism and a second pressing mechanism. A plurality of groups of compression rollers are arranged in the mounting shell and are driven by a motor to rotate; the first pressing mechanism is used for continuously bending the steel plate; the second pressing mechanism is used for conducting continuous secondary bending on the steel plate and pressing the edge sealing steel belt and the edge of the steel plate. The first pressing mechanism is matched with the conveying belt mechanism, so that a steel plate and an edge sealing steel belt can be continuously bent, and the edge of the steel plate is bent; and through cooperation of the second pressing mechanism and the conveying belt mechanism, the edge of the steel plate can be continuously bent towards the interior of the edge sealing steel belt again, the connecting position of the steel plate and the edge sealing steel belt is pressed, the stability of the connecting position is improved, the pressing efficiency is improved, the working continuity is high, and the machining efficiency is improved.

The invention discloses a miR-144-3p inhibitor for relieving fish intestinal injury induced by oxidized fish oil and application, and belongs to the technical field of aquatic animal nutrition physiological regulation and control. The miR-144-3p inhibitor is injected into the intraperitoneal cavity of megalobrama amblycephala, transcription of an oxidative stress core regulatory element Nrf2 is up-regulated, overexpression of autophagy and apoptosis related genes induced by intake of oxidized fish oil is inhibited, damage of an intestinal tight junction structure is improved, and the active oxygen level and the autophagy and apoptosis level of intestinal cells are reduced. The method can quickly, efficiently and specifically relieve intestinal barrier injury, oxidative stress and intestinal cell apoptosis induced by oxidative rancidity of freshwater fish feed grease and the like, and healthy and efficient culture of freshwater fish is achieved.

A laser speckle suppression device relates to the technical field of optical display. The laser speckle suppression device comprises an optical sheet, a base, a driving assembly and a moving assembly, wherein the base, the driving assembly and the moving assembly are sequentially stacked. The optical sheet is arranged on the face, facing or deviating from the base, of the moving assembly. The moving assembly comprises a hollow elastic piece, and the driving assembly can drive the elastic piece to move in the first direction or the second direction on the plate face. Or the moving assembly comprises a hollow inner elastic piece and an outer elastic piece arranged outside the inner elastic piece in a sleeving mode, the outer elastic piece is of a hollow structure, the hollow portion of the outer elastic piece and the hollow portion of the inner elastic piece are coaxially arranged, and the driving assembly drives the inner elastic piece to move in the first direction and drives the outer elastic piece to move in the second direction on the plate face so that the laser beams entering the optical piece can be overlapped, therefore, laser speckles are inhibited, and imaging chromatic aberration is optimized; the first direction is perpendicular to the second direction. The device can adjust the number of the elastic pieces and the assembling positions of the optical pieces according to application scenes, and the applicability and diversity of the device structure are improved.

The utility model discloses integrated pressing equipment for manufacturing a split type end socket, which belongs to the technical field of split type end socket manufacturing and comprises a pressing cushion table, a supporting device and a pressing machine, the supporting device is used for placing and transferring end socket pieces, the pressing machine is used for pressing the end socket pieces, and the pressing cushion table is fixedly connected under the pressing machine. The supporting device is located between the pressing cushion table and the pressing machine, and the two sides of the supporting device are respectively connected with a moving device used for transferring the supporting device. The split type end socket is prepared in an integrated pressing mode, so that the pressing efficiency and the yield of the split type end socket are improved; the moving device is convenient for transferring and unloading the formed split type end socket, a plurality of supporting devices can be matched with the moving device for continuous pressing, the forming efficiency of the split type end socket is greatly improved, the forming effect of integrated pressing is good, the matching precision of all end socket pieces is high, and later welding is facilitated.

The invention discloses a production method for reducing nitrogen and increasing efficiency of greenhouse cucumbers, including applying basal fertilizer and applying topdressing. When applying basal fertilizer, the original organic fertilizer and diammonium phosphate are reduced by 5-15% respectively, and at the same time, a certain proportion of N-butylthiophosphoric acid triamide and DMPP (3,4-dimethyl pyrazole phosphate) are added respectively according to the nitrogen content in the basal fertilizer. In the topdressing stage, a certain proportion of DMPP and PHH are applied according to the nitrogen content in the topdressing (urea is calculated as 47% and diammonium phosphate is calculated as 18%) at the seedling stage, the initial flowering stage, the melon-setting stage and the peak melon stage; and quick-acting organic boron fertilizer is applied at the same time. The production method makes full use of the advantageous combination of nitrification inhibitors and trace elements, effectively regulates the nitrification of nitrogen in greenhouse soil, reduces the application of nitrogen fertilizer, and improves the utilization efficiency of nitrogen fertilizer. While greatly reducing production costs, the purpose of increasing production and income is achieved, and at the same time, the acidification of the soil is improved to a certain extent.

The utility model relates to a tea leaf flattening forming machine which comprises a base, supporting columns are fixedly connected to the four corners of the top of the base, a cover plate is connected to the tops of the supporting columns, a hydraulic machine is fixedly connected to the top of the cover plate, and an output shaft of the hydraulic machine penetrates through the cover plate and is connected with a compression mechanism. A pressing table is fixedly connected to the position, under the compressing mechanism, of the top of the base. The utility model relates to the technical field of tea processing equipment. According to the tea leaf flattening and forming machine, through the arranged compression mechanism, high-frequency vibration can be applied to a pressed tea cake when tea leaves are pressed, so that the tea cake is compressed more uniformly, secondary processing of the tea cake is avoided, and the pressing efficiency of the tea cake is effectively improved.

The invention provides a low-frequency ultra-wideband SAR radio frequency interference suppression method based on two-dimensional frequency domain notching. The method performs two-dimensional Fourier transform on an echo signal received by a low-frequency ultra-wideband SAR to obtain an echo signal in the two-dimensional frequency domain; calculates the average value and standard deviation of the two-dimensional frequency domain echo signal, and takes the sum of the average value and three times the standard deviation as a suppression threshold. In this process, the size of the threshold can also be adjusted according to the energy of the radio frequency interference signal to achieve a better suppression effect; then, a notch process is performed by using a "1" method, and a value greater than the threshold is set as the average value to achieve the purpose of suppressing the radio frequency interference signal; finally, the two-dimensional frequency domain echo signal after the radio frequency interference suppression is transformed into a two-dimensional time domain to complete the suppression of the radio frequency interference signal.

The invention relates to a compound targeting PDE4B enzyme and application thereof, in particular to a compound with a structure shown in a general formula (I) or a stereoisomer, a tautomer, a pharmaceutically acceptable salt, a hydrate or a solvate thereof, in the formula (I), Y and Z are independently selected from none or # imgabs0 #, R11 is selected from H, alkyl, chlorinated alkyl and C5-C6 rings; r1 and R2 are independently selected from H, alkyl containing a substituent group or not containing a substituent group, and C3-C10 rings containing a substituent group or not containing a substituent group, wherein the substituent groups comprise halogen, amide, amino, hydroxyl, carboxyl, nitro, cyano, alkyl, alkoxy, alkylthio, C3-C10 cycloalkyl, C4-C10 heterocycloalkyl, C6-C10 aryl or C5-C10 heteroaryl; and R3 is selected from H, a C1-C20 alkyl group, a C1-C20 hetero-alkyl group, a C3-C10 cycloalkyl group, a C4-C10 hetero-alkyl group, a C6-C10 aryl group and a C5-C10 hetero-aryl group which contain or do not contain a substituent group. # imgabs1 #

This invention relates to the technical field of waste aluminum recycling equipment, specifically disclosing a hydraulic feeding and processing device for waste aluminum recycling. The device includes a processing chassis with a rotating pressing mold inside. A rotary servo motor for driving the rotating pressing mold is fixedly installed in the center of the top of the chassis. The ejector structure utilizes the downward power of the main pressing component, which is converted into the upward power of the ejector component through gear and toothed plate meshing. This eliminates the need for a separate drive device and corresponding control unit for the ejection process, effectively simplifying the overall power layout and reducing manufacturing costs. The pressing and ejecting actions are executed synchronously, with highly matched process cycles. Combined with an ejector component featuring automatic reset, the flatness of the cavity bottom surface can be maintained even without ejector operation, ensuring the quality of the formed end face of the waste aluminum block.

The invention discloses a carbon quantum dot asphaltene inhibitor modified by a hydrophobic long carbon chain as well as a preparation method and application of the carbon quantum dot asphaltene inhibitor, and belongs to the technical field of oil field plug removal. The preparation method comprises the following steps: dissolving citric acid and ethidene diamine in distilled water, and after a heating reaction is finished, centrifugally collecting supernate to obtain a carbon quantum dot solution; adding an inorganic acid solution, and carrying out oxidation reaction, washing and drying to obtain carboxylated carbon quantum dots; the preparation method comprises the following steps: preparing a hydrophobic long carbon chain modified carbon quantum dot asphaltene inhibitor, uniformly mixing the hydrophobic long carbon chain modified carbon quantum dot asphaltene inhibitor with N-amino polyhexylamine and a solvent, adding a coupling agent, carrying out an amidation reaction, and carrying out rotary evaporation, water washing, centrifugation and drying to obtain the hydrophobic long carbon chain modified carbon quantum dot asphaltene inhibitor. Strong adsorption is formed through interaction with asphaltene molecules through pi-pi interaction, electrostatic attraction, hydrogen bonds, Van der Waals force and the like. The grafted hydrophobic long carbon chain forms large steric hindrance among asphaltene molecules, formation of large-scale parallel stacking is hindered, direct contact and aggregation of the asphaltene molecules are prevented, and the efficiency of the inhibitor is remarkably improved.

This invention discloses a deep learning-based intelligent interference management system for wireless communication networks, belonging to the field of communication network management technology. By processing and fusing multipath, mobility, and environmental factors, it can solve the problem of inaccurate channel state information caused by traditional models ignoring non-stationary interference. The constructed sequence simultaneously captures temporal trends and spatial cooperation, providing high-quality input for subsequent adaptive models. Through meta-learning pre-training to obtain cross-scenario general parameters, online fine-tuning achieves millisecond-level adaptation to dynamic channels, and finally outputs accurate interference prediction, which can significantly improve the model's adaptability to complex channels and the real-time performance of interference estimation, providing key support for the anti-disturbance capability of trajectory control. Through the synergistic cooperation of the above steps, the pre-training stage lays the foundation for cross-scenario generalization, the online fine-tuning stage quickly adapts to new scenarios, and the interference prediction stage outputs key compensation information, forming a closed-loop logic of pre-training, fine-tuning, and prediction.

This utility model relates to the field of Caragana korshinskii pellet feed production technology, specifically a Caragana korshinskii pellet feed press that is easy to clean. It includes a base, with support legs installed around the bottom of the base, a pressing component installed at the center of the bottom of the base, and a device body installed on the top of the base. Quick-release components are installed around the outer perimeter of the device body. The improved feed press allows for easy disassembly and assembly of the feed hopper, eliminating the need for cumbersome steps and facilitating cleaning. Furthermore, both the grinding disc and the pressure rollers are detachable, enabling workers to easily disassemble and clean them, effectively reducing clogging and preventing material deterioration due to prolonged accumulation. This increases pressing efficiency while ensuring the quality of the pressed material.

The present invention discloses the application of 2-furancarboxylic acid in inhibiting soil nitrification, and belongs to the field of environmental protection and nitrification inhibitors. 2-furancarboxylic acid and nitrogen fertilizer are formulated into a mixed solution and applied to the soil, wherein the application amount of 2-furancarboxylic acid in the soil is 100-5000 mg / kg soil. The 2-furancarboxylic acid of the present invention can efficiently inhibit soil nitrification at low doses, reduce farmland nitrogen loss and soil N2O emissions, and the inhibition efficiency is higher than other nitrification inhibitors. The 2-furancarboxylic acid of the present invention has a stable chemical structure and is a type of "green" biological nitrification inhibitor based on plants, which can solve the problems of high price, unstable effect and easy pollution to the environment and food safety of existing nitrification inhibitors.

The present application relates to the field of molecular biology, in particular to the use of LMO7 inhibitor in the preparation of glioma treatment products, the present application adopts the siRNA obtained by RNAi method or the nucleic acid construct containing the siRNA sequence, the lentivirus, the expression of human LMO7 gene is down-regulated, and the proliferation and migration of glioma cells can be effectively inhibited, therefore the LMO7 inhibitor of the present application can be used in the preparation of the drug for treating brain glioma, thereby treating brain glioma, and opening up a new direction for brain glioma treatment.

The invention relates to the technical field of fire suppression systems, in particular to a fire suppression system and method for an energy storage power station, and the system comprises a fire detection module, a control processing module, a fire extinguishing agent supply module, a man-machine interaction module with an early warning function, a power management module, and a system self-inspection module. The fire detection module comprises a particle sensor, a smoke sensor and a temperature sensor, wherein the particle sensor and the smoke sensor are used for monitoring smoke concentration in air; through cooperation of the fire detection module, the control processing module, the fire extinguishing agent supply module, the man-machine interaction module with the early warning function and the power management module, automatic monitoring, early warning, control processing, fire extinguishing operation, man-machine interaction and other functions of the fire of the energy storage power station are achieved; the fire alarm can be detected when the fire behavior is not obvious yet but enough heat is generated, so that a prime number rescue worker can handle the fire in time, and the fire suppression efficiency is improved.

The present invention discloses a METTL6 gene inhibitor and its application, and relates to the field of molecular biology. The inhibitor is one of siRNA, shRNA or METTL6 gene interference lentivirus that inhibits the expression of the METTL6 gene; wherein the target sequence of the siRNA is as shown in SEQ ID NO.1 or SEQ ID NO.2; the shRNA nucleotide sequence sense chain is as shown in SEQ ID NO.3, and the antisense chain is as shown in SEQ ID NO.4; or the sense chain is as shown in SEQ ID NO.5, and the antisense chain is as shown in SEQ ID NO.6. The inhibitor of the present invention can effectively inhibit the expression of the METTL6 gene, has a high inhibitory efficiency on the cell proliferation, cell migration and invasion of cancer cells, and has a good prospect for drug development.

The invention belongs to the technical field of biological medicine, and particularly relates to the field of gene therapy and pain therapy. The invention provides an sgRNA and AAV-CRISPRi virus system for targeted inhibition of TRPV1 gene, the AAV-CRISPRi virus system is a CRISPRi system based on AAV delivery, and the core functional structure sequence of the AAV-CRISPRi virus system is a 5 '-ITR inverted repeat sequence, an EF1 alpha core promoter, a ZIM3 transcription inhibition structural domain, a linker, a sadCas9-NLS nuclear localization signal-SV40 poly (A) termination signal-U6 promoter, and an sgRNA-3'-ITR inverted repeat sequence, according to the core functional structure, the miniaturization of a CRISPRi system is realized, and the infection success rate and the target gene inhibition efficiency are improved while the plasmid construction and AAV packaging costs are reduced. The AAV-CRISPRi virus system for targeted inhibition of the TRPV1 gene is used for preparing drugs for chronic pain, and has the characteristics of high efficiency, strong specificity and few side effects.

The invention belongs to the technical field of biology, and particularly relates to a dsRNA synergist, and application and a method of the dsRNA synergist in improving the RNAi efficiency of lepidoptera pests. By analyzing factors influencing the RNAi efficiency of the ostrinia furnacalis, a gene which can be induced to be up-regulated by dsRNA and is named as REX4 gene is found, REX4 protein coded by the gene is found to be capable of directly degrading the dsRNA under in-vitro conditions, the degradation efficiency is relatively high, aspartic acid at a first catalytic site is mutated into glycine, and the gene can be used for degrading the dsRNA at a second catalytic site. And the nucleic acid degradation capability of the REX4 protein is obviously reduced. Insect RNAi efficiency can be improved by inhibiting expression of the REX4 gene, and the gene generally exists in lepidoptera insects. The REX4 protein provided by the invention can be used as a core target for improving the RNAi efficiency of the lepidoptera pests, the problem of low RNAi efficiency of the lepidoptera pests is solved, and the application of the RNAi technology in agricultural pest control is promoted.