Hydroxypropyl starch empty capsule and preparation method thereof

Abstract

The invention discloses a hydroxypropyl starch empty capsule, which is prepared from the following components (by weight): 100-110 parts of hydroxypropyl starch, 15-25 parts of gel, 2-3 parts of coagulant aids, 0.5-1.5 parts of a plasticizer, 0.8-2 parts of nanometer superfine calcium carbonate and 1000-1200 parts of water. Meanwhile, the invention further discloses a preparation method of the hydroxypropyl starch empty capsule. The empty capsule prepared by the preparation method has high toughness, is not easy to break and has good stability; in addition, the raw materials are cheap in price, the cost is low, and there is no environmental pollution in the production process.

Description

technical field [0001] The invention relates to the technical field of starch modification, in particular to a hydroxypropyl starch hollow capsule and a preparation method thereof. Background technique [0002] Ordinary capsules can be divided into hard capsules and soft capsules, and hard capsules are also called "hollow capsules". The hollow capsule is composed of a cap and a body two-section capsule shell refined from gelatin and auxiliary materials. It is mainly used to hold solid and liquid medicines. , Capsules can also effectively mask the unpleasant taste and smell of the contents, and are the most popular dosage form for consumers. [0003] Our country needs about 250 billion medicinal capsules every year, and more than 95% of them are animal gelatin capsules. It has been found that, for example: 1. Gelatin is easy to cross-link with drugs such as aldehydes, reducing sugar-based compounds and vitamin C, which makes the water solubility of capsules worse, leading t...

AI Technical Summary

Problems solved by technology

[0003] Our country needs about 250 billion medicinal capsules every year, and more than 95% of them are animal gelatin capsules. It has been found that, for example: 1. Gelatin is easy to cross-link with drugs such as aldehydes, reducing sugar-based compounds and vitamin C, which makes the water solubility of capsules worse, leading to the disintegration of empty capsules and the delay of dissolution of capsule contents; Electrostatic charge accumulation can occur under dry conditions, which greatly affects subsequent production and processing; 3. When stored in a low-humidity environment for a long time, gelatin capsules tend to become brittle and cause the capsules to break; 4. Gelatin is an animal-derived component. factors, thus making gelatin rejected by certain groups of people in the world

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