Phase-change cooling stent as well as preparation method and phase-change cooling combined stent thereof

Abstract

The invention relates to the technical field of stents used in ophthalmology departments and in particular relates to a phase-change cooling stent as well as a preparation method and a phase-change cooling combined stent thereof. The invention provides the phase-change cooling stent which comprises a spiral shell and a core material, wherein the spiral shell is of a hollow structure; the core material is filled into the spiral shell; the core material is a phase-change cooling material; the spiral shell is a medical polymer material; and the outer diameter of the phase-change cooling stent isadaptive to the inner diameter of a Schlemm's canal. According to the phase-change cooling stent, the phase-change cooling material is adopted as a core layer component, the phase-change cooling material automatically absorbs heat from or releases heat to the environment through phase or structure change of self, so that the purpose of regulating and controlling ambient temperatures is achieved; by virtue of the properties that partial temperatures of trabecular meshwork tissue can be reduced by the phase-change cooling material, and wrong folding or accumulation of proteins of trabecular meshwork cells is reverted or blocked through a low temperature environment, the state that out-flowing of an aqueous fluid is blocked can be alleviated, and through repeated actions of the phase-change process, an effect that intraocular pressure is continuously reduced through one time of interference can be achieved.

Description

technical field [0001] The invention relates to the technical field of ophthalmic brackets, in particular to a phase-change cooling bracket, a preparation method thereof, and a phase-change cooling combined bracket. Background technique [0002] Glaucoma is the world's first irreversible blinding eye disease, mainly divided into primary angle-closure glaucoma (Primary Angle-closure Glaucoma, PACG) and primary open-angle glaucoma (Primary Open-angle Glaucoma, POAG). With the development of my country's social economy and the change of people's lifestyle, POAG has become the most common irreversible and highly blinding eye disease in my country, accounting for 70.4% of the total number of glaucoma patients. Elevated intraocular pressure is considered to be an important factor in the pathogenesis of glaucoma, and it is also the only factor that can be intervened at present. Increased drainage resistance of aqueous humor is considered to be the main cause of elevated intraocular...

AI Technical Summary

Problems solved by technology

Medication is usually the first choice, but almost all currently available medications need to be used at least once a day to be effective, which has many serious side effects, including: congestive heart disease, shortness of breath, high blood pressure, Depression, kidney stones, aplastic anemia, and sexual dysfunction; medication compliance is also a major problem, and it is estimated that more than half of glaucoma patients do not follow their correct timed doses, causing fluctuations in intraocular pressure and optic nerve damage and visual field defect

Laser trabeculoplasty or trabeculectomy is often performed when medications are insufficient to reduce intraocular pressure, and such interventions have the potential to scar the scleral flap, closing artificially created outflow channels for aqueous humor, causing intraocular pressure Elevated again; at the same time, a pathway for bacteria on the surface of the eye and eyelids to enter the interior of the eye is also formed, and an inner eye infection called endophthalmitis can occur, which often results in permanent and more severe vision loss

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