A method that greatly accelerates the enzyme-catalyzed conversion of carbon dioxide to formic acid
A carbon dioxide and formic acid technology, applied in the field of enzyme catalysis reaction, can solve the problems of accelerated reusability, acceleration, poor reusability, etc., and achieve the effects of improving reusability, simple and easy operation, and simplified preparation method
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Embodiment 1
[0072] A method that can greatly accelerate the enzyme-catalyzed conversion of carbon dioxide into formic acid, where the enzyme-catalyzed CO 2 In the reaction system converted to formic acid, add PDA / PEI-SiO 2 -CA, then into CO 2 The gas is maintained at a certain pressure and reacts in a constant temperature oscillator. The reaction system contains 1mg / mL FDH and 50mM NADH, and the reaction is carried out at a concentration of 0.05M phosphate buffer (pH6.0), at a temperature of 37°C, a pressure of 0.5MPa, and an oscillator speed of 170rpm; PDA / PEI-SiO 2 -The consumption of CA is 0.2g / mL, after reacting 10min, formic acid output is 0.235mM, and reaction rate is 1.41mM / h, is 47 times of control experiment system (see attached Figure 4 ).
[0073] The formic acid output of the control experimental system without any addition was 0.05mM after 10min of reaction; adding the same mass (0.2g / mL) of PDA / PEI-SiO 2 In the system, the formic acid output after 10min of reaction was ...
Embodiment 2
[0078] A method that can greatly accelerate the enzyme-catalyzed conversion of carbon dioxide into formic acid, where the enzyme-catalyzed CO 2 In the reaction system converted to formic acid, add PDA / PEI-SiO 2 -CA, then into CO 2 The gas is maintained at a certain pressure and reacts in a constant temperature oscillator. The reaction system contains 0.2mg / mL FDH and 100mM NADH, and the reaction is carried out in 0.1M phosphate buffer (pH6.5), the temperature is 30°C, the pressure is 2MPa, the oscillator speed is 120rpm, PDA / PEI-SiO 2 -The dosage of CA is 0.5g / mL, after 30 minutes of reaction, the output of formic acid is 0.142mM, and the reaction rate is 0.852mM / h, which is obtained by adding PDA / PEI-SiO 2 -30 times before CA. PDA / PEI-SiO 2 - After CA was centrifuged from the reaction solution, it was washed 2-3 times with 0.1M phosphate buffer (pH 6.5) and then used again. When it was used for the 10th time, the effect was 93% of that when it was used for the first time....
Embodiment 3
[0082] A method that can greatly accelerate the enzyme-catalyzed conversion of carbon dioxide into formic acid, where the enzyme-catalyzed CO 2 In the reaction system converted to formic acid, add PDA / PEI-SiO 2 -CA, then into CO 2 The gas is maintained at a certain pressure and reacts in a constant temperature oscillator. The reaction system contains 2mg / mL FDH and 10mM NADH, and the reaction is carried out in 0.2M phosphate buffer (pH6.8), the temperature is 40°C, the pressure is 1MPa, the oscillator speed is 150rpm, PDA / PEI-SiO 2 -The dosage of CA is 0.4g / mL, after 20min of reaction, the output of formic acid is 0.314mM, and the reaction rate is 0.942mM / h, which is obtained by adding PDA / PEI-SiO 2 -42 times before CA. PDA / PEI-SiO 2 - After CA was centrifuged from the reaction solution, it was washed with 0.2M phosphate buffer (pH6.8) for 2 to 3 times and then used again. When it was used for the 10th time, the effect was 96% of that when it was used for the first time. ...
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