External traditional Chinese medicine composition for treating acne, and preparation method thereof

Abstract

The invention discloses an external traditional Chinese medicine composition for treating acne, and a preparation method thereof. The external traditional Chinese medicine composition is prepared from, by weight, 10-50 parts of radix sophorae flavescentis, 10-50 parts of cortex dictamni, 5-30 parts of radix stemonae, 5-15 parts of cortex phellodendri, 1-8 parts of radix et rhizoma rhei and 1-10 parts of caulis sargentodoxae. The method comprises the following steps: (1) preparing raw materials; (2) soaking the radix sophorae flavescentis, cortex dictamni, radix stemonae and cortex phellodendriin water, performing extraction to obtain radix sophorae flavescentis extract, cortex dictamni extract, radix stemonae extract and cortex phellodendri extract; (3) mixing and filtering the radix sophorae flavescentis extract, the cortex dictamni extract, the radix stemonae extract and the cortex phellodendri extract to obtain a purified filtrate; (4) performing evaporative concentration; (5) drying the radix et rhizoma rhei and caulis sargentodoxae, grinding, and carrying out ultrafine grinding; and (6) putting the mixed powder into the above obtained concentrate, adding a preservative and ahumectants, and dispersing, homogenizing, shearing and refining the mixed material by adopting a homogenizing and emulsifying machine to prepare a paste. The production efficiency can be effectively improved, loss of effective components of the medicines is reduced, and the medicine effect is enhanced; and the product is convenient to carry and use, and has a good market prospect.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and relates to an external Chinese medicinal composition for treating acne and a preparation method thereof. Background technique [0002] Acne is a common chronic inflammatory skin disease that mainly occurs in the pilosebaceous unit of the face of adolescents. Pleomorphic skin lesions such as nodules are mainly found on the face, back, chest and other parts rich in sebaceous glands. The occurrence of acne is mainly related to factors such as excessive sebum secretion, blockage of pilosebaceous gland ducts, bacterial infection, and inflammatory response; after puberty, the level of androgen in the human body increases, and the sebaceous glands develop vigorously and produce a large amount of sebum. Abnormal keratinization of the pilosebaceous duct will cause duct blockage, sebum discharge obstruction, and then form keratin plugs, that is, micropowders. A variety of microor...

AI Technical Summary

Problems solved by technology

[0003] At present, modern medicine mainly uses retinoic acid, antibiotics, hormones and other drugs for treatment, but there are certain drug resistance and adverse drug reactions, and the effective rate is not ideal

At present, there are a variety of traditional Chinese medicine external treatment products for acne treatment on the market. In terms of preparation process, most products adopt a single extraction method or simply pulverized and mixed with a solvent. The content of active ingredients in the products is low, or due to Extraction process limitation, loss of non-water-soluble components; or due to the volume and dosage of raw materials, there are many lignin and cellulose components in the product, so that the content of active ingredients in the unit volume is too small, which affects the curative effect and is inconvenient to use