Degradable anti-infection lithiasis-preventing Fe-Cu series alloy applicable to urinary implant material

Abstract

The invention belongs to the field of biomedical materials and particularly provides degradable anti-infection lithiasis-preventing Fe-Cu series alloy applicable to a urinary implant material. The alloy comprises the following components in percentage by weight: 0.2% to 5.0% of Cu, 0 to 35% of Mn, 0 to 1.5% of C, 0 to 0.6% of N and the balance Fe. Aiming at the problems that urinary tract implantsare undegradable, susceptible to infection, prone to forming stone and the like, the degradable anti-infection lithiasis-preventing Fe-Cu series alloy achieves a sterilization effect by releasing Cuions and simultaneously inhibits formation of bacterial biofilms at the surface by surface degradation and sterilization effect, thereby preventing formation and growth of stone taking bacterial filmsas the center; meanwhile elements including Mn, C and N can be selectively added; and the austenization and degradation speed of the alloy are regulated so that the alloy can be degraded and metabolized in a biotic environment in a body after a surgery without being taken out for the second time. Therefore, the problems about infection and stone formation of the urinary tract implants are effectively solved, and clinical actual problems can be solved, so the degradable anti-infection lithiasis-preventing Fe-Cu series alloy meets the current advanced medical treatment conception and the requirements of human bodies and is a new direction of development of urinary implant material.

Description

technical field [0001] The invention belongs to the field of biomedical materials, in particular to a degradable anti-infection and anti-calculus Fe-Cu alloy suitable for urinary implant materials. Background technique [0002] A variety of urinary tract lesions in the urinary system require tissue resection followed by urethral passage reconstruction. At present, the ureter-bladder anastomosis not only requires high technical requirements, but also prone to urinary fistula or anastomotic stenosis. A new technique is the use of staples. In addition, ureteral obstruction usually requires the introduction of a stent to resolve the stricture. Interventional treatment with implants such as staples and stents can make the operation efficient and precise. However, urinary tract infections and stones caused by implants are very difficult, and the incidence rate remains high, which brings huge physical pain and heavy burden to patients. Economic burden, while limiting the widespre...

AI Technical Summary

Problems solved by technology

Interventional treatment with implants such as staples and stents can make the operation efficient and precise. However, urinary tract infections and stones caused by implants are very difficult, and the incidence rate remains high, which brings huge physical pain and heavy burden to patients. Economic burden, while limiting widespread use of implantable devices

[0003] Bacterial infection caused by implants is one of the key factors leading to the failure of surgery. Foreign objects disturb the normal operation system in the body, easily destroy the body's defense barrier, affect the normal flushing effect of the urinary tract on bacteria, and increase the chance of retrograde infection

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