Method for preparing taurine from sodium isethionate

Abstract

The invention provides a method for preparing taurine from sodium isethionate. The method comprises the following steps: catalyzing the reaction between sodium isethionate and ammonia by using a heterogeneous catalyst to generate sodium taurate, then neutralizing, crystallizing, separating and the like to obtain the finished product taurine, wherein the heterogeneous catalyst is one or more of Zr2MoO4 (PO4) 2, ZrMo2O8 or MoO3. Compared with a traditional basic catalyst, the process has the advantages that the temperature and the pressure of the sodium hydroxyethyl sulfonate ammonolysis reaction can be remarkably reduced, the reaction time is shortened, and the adopted catalyst is easy to separate and recover and is suitable for industrial production.

Description

technical field [0001] The invention relates to a method for preparing taurine from sodium isethionate. Background technique [0002] The chemical name of taurine is 2-aminoethanesulfonic acid, which is an essential non-protein amino acid for the human body and exists in almost all organs of humans and mammals in free form. Since taurine was first discovered in ox bile, it is also known as taurine and ox bile. The role of taurine is different from that of other amino acids. It is not an essential amino acid for protein composition, but it is essential in the body, similar to a body regulatory factor. According to research, taurine can promote the growth and development of the nervous system, protect the brain and improve memory. It can also improve optic nerve conduction and visual function. It also has many important functions such as protecting the heart and preventing cardiovascular and cerebrovascular diseases. Taurine has high medicinal and medical value, is an import...

AI Technical Summary

Problems solved by technology

[0005] The reaction of sodium isethionate and liquid ammonia to prepare sodium taurate is a key synthesis step of the ethylene oxide method. In the initial research, since no catalyst was added, it required high temperature of 200-280°C and high pressure of 14-21MPa. Reaction conditions, so the energy cost of the reaction process is high, and there are certain safety risks

[0006] Chinese patent CN107056659A discloses a method of selecting alkali metal hydroxide or carbonate as a homogeneous catalyst in the ammonolysis reaction process. cannot be recycled

[0008] Chinese patent CN105732440A discloses that in the ammonolysis reaction process containing mother liquor, alkali metal hydroxides, alkali metal carbonates (including acid carbonates), iron series / aluminum series metal salts, NiO / CeO can be added 2 , any one of rare earth oxides or their combination as a catalyst, the yield of sodium taurate can be increased to 90-95%, but the reaction still requires a high temperature of 255-265 ° C and a pressure of 19-20 MPa

[0009] In summary, the catalyst system adopted in the ammonolysis reaction of the existing taurine preparation process is still a homogeneous catalyst, and there is a problem that the catalyst is difficult to recycle. At the same time, the reaction conditions are still relatively harsh, and the process conditions need to be improved to reduce Energy consumption and risks in the production process, reducing production costs

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