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Preparation method and application of anti-hydropericardium syndrome feed additive

A feed additive, pericardial effusion technology, applied in the application, animal feed, animal feed and other directions, can solve the problems of high cost and poor effect, and achieve the effects of low cost, reduced mortality, and good water solubility

Inactive Publication Date: 2020-08-04
黑龙江省农业科学院畜牧兽医分院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The present invention provides a preparation method and application of an anti-chicken pericardial effusion syndrome feed additive in order to solve the problems of high cost and poor effect of the current vaccine prevention method for chicken pericardial effusion syndrome

Method used

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  • Preparation method and application of anti-hydropericardium syndrome feed additive
  • Preparation method and application of anti-hydropericardium syndrome feed additive

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Experimental program
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specific Embodiment approach 1

[0013] Specific embodiment 1: The preparation method of the feed additive for anti-chicken pericardial effusion syndrome in this embodiment is carried out according to the following steps:

[0014] 1. Preparation of egg yolk antibody solution for chicken pericardial effusion syndrome: egg yolk solution containing chicken pericardial effusion syndrome antibody, 1.5%-2% sodium chloride aqueous solution and 10%-11% PEG6000 solution by volume Stir and mix at a ratio of 1:1:1, then filter with a 60-mesh sieve and place it at 3~5℃ for 11~13h, then centrifuge to remove precipitation to obtain the supernatant, which is filtered and sterilized , That is, the yolk antibody solution of chicken pericardial effusion syndrome is obtained;

[0015] 2. Preparation of yolk antibody freeze-dried powder for chicken pericardial effusion syndrome: add formaldehyde, thimerosal, vitamin C, polyvinylpyrrolidone, glycine, and sorbitol to the yolk antibody solution of chicken pericardial effusion syndrome i...

specific Embodiment approach 2

[0052] Specific embodiment two: This embodiment is different from the specific embodiment one in that the stirring and mixing time described in step one is 8-12 min, and the stirring is sufficient. Others are the same as the first embodiment.

specific Embodiment approach 3

[0053] Specific embodiment three: This embodiment is different from specific embodiment one in that the centrifugation described in step one is centrifugation at a speed of 4000-6000 r / min for 15-25 minutes. Others are the same as the first embodiment.

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Abstract

The invention relates to a preparation method and application of a feed additive, in particular to a preparation method and application of an anti-hydropericardium syndrome feed additive. The invention solves the problems of high cost and poor effect of the existing method for preventing the hydropericardium syndrome by using the vaccine. The preparation method comprises the following steps of: 1,preparing an egg yolk antibody solution of the hydropericardium syndrome; 2, preparing egg yolk antibody freeze-dried powder of the hydropericardium syndrome; and 3, mixing the egg yolk freeze-driedpowder with astragalus polysaccharide, angelica polysaccharide and lycium barbarum polysaccharide to obtain the feed additive. The invention also discloses application of the feed additive in resisting the hydropericardium syndrome. The method is simple and low in cost, the death rate of chicken suffering from the hydropericardium syndrome is reduced to 8% or below in the application of resistingthe hydropericardium syndrome, and the effect is good.

Description

Technical field [0001] The invention relates to a preparation method and application of a feed additive. Background technique [0002] Chicken pericardial effusion syndrome is mainly caused by type 4 avian adenovirus infection. It is an acute infectious disease in chickens with pale yellow liquid in the pericardium as the main clinical symptom. Inclusion body hepatitis is also common. Sick chickens usually appear depressed and die. The rate can reach 90%. Since 2015, it has spread rapidly in China’s Henan, Hebei, Liaoning, Jilin, Xinjiang, Anhui, Shandong, Jiangxi, Hubei, and Jiangsu provinces. Since 2016, outbreaks have occurred in different areas in Heilongjiang Province, giving the chicken industry Caused serious economic losses. [0003] At present, chicken pericardial effusion syndrome caused by avian adenovirus type 4 is mainly prevented by vaccination, but there is no self-developed commercial vaccine in China. Generally, foreign vaccines are used and the cost is relativel...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23K50/75A23K10/20A23K20/163A23L3/3499A23L3/3535A23L3/3544A23L3/3508A23L3/349A23L3/3562A61K35/57A61K39/395A61P31/20
CPCA23K50/75A23K10/20A23K20/163A23L3/3499A23L3/3535A23L3/3544A23L3/3508A23L3/349A23L3/3562A61K35/57A61K39/395A61P31/20
Inventor 朱庆贺苗艳杨旭东王观悦王爽陈曦刘雪松兰世捷张鹏宇田秋丰张备张红刘秋瑾秦平伟姚瑞武晓东邱景会江波涛史同瑞高佳滨宋国希姚橹李白
Owner 黑龙江省农业科学院畜牧兽医分院
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