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Antibacterial silk thread suture line with dual-photoresponse function and preparation method thereof

A light-responsive, suture technology, applied in the field of silk sutures, can solve the problems of weak antibacterial effect of sutures and inability to achieve controllable degradation, and achieve the effects of controllability of degradation, safe use, and mild yellow light

Inactive Publication Date: 2020-08-21
NANCHANG UNIV
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  • Abstract
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  • Claims
  • Application Information

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Problems solved by technology

[0003] The purpose of the present invention is to solve the above problems, provide a kind of antibacterial silk suture with double light response function and its preparation method, to solve the technical problems such as weak antibacterial effect of existing suture, can not realize controllable degradation, etc., used in the present invention The technical solution is:

Method used

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  • Antibacterial silk thread suture line with dual-photoresponse function and preparation method thereof
  • Antibacterial silk thread suture line with dual-photoresponse function and preparation method thereof
  • Antibacterial silk thread suture line with dual-photoresponse function and preparation method thereof

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Embodiment

[0026] Example: see Figure 1-6 .

[0027] An antibacterial silk suture with double-light response function and a preparation method thereof, the preparation process comprising the following steps:

[0028] 1) Dissolve 0.56g NH3•H2O, 2.975g Zn(NO3)2•6H2O and 0.7g C6H12N4 in 20ml of deionized water in turn, and stir for 10min to obtain solution A;

[0029] 2) The obtained solution A was subjected to constant temperature reaction at 65°C for 15 minutes to obtain solution B;

[0030] 3) Take 100ml of solution B, add 0.14g of sodium citrate, 0.1g of hydroxypropyl methylcellulose, 0.1g of carbon powder and 0.1g of lignin to it in turn, and react at a constant temperature of 85°C for 12h;

[0031] 4) Wash the product obtained in step 3) twice with purified water, then twice with absolute ethanol, and then twice with purified water;

[0032] 5) The product obtained in step 4) was subjected to vacuum freeze-drying, and then pyrolyzed in a microwave oven for 15 minutes to obtain por...

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Abstract

The invention discloses an antibacterial silk thread suture line with a dual-photoresponse function and a preparation method of the antibacterial silk thread suture line. The zinc nitrate hexahydrate,ammonia water and hexamethylenetetramine are used as main raw materials, after one-step reaction, the main raw materials react with sodium citrate, hydroxypropyl methyl cellulose, carbon powder and lignin, and an obtained product is subjected to freeze drying and microwave treatment to obtain porous zinc oxide; the porous zinc oxide is loaded on the silk thread to obtain the antibacterial silk thread suture line with the dual-photoresponse function, the antibacterial performance of the porous zinc oxide can be further enhanced under the excitation of yellow light, and the zinc oxide is heatedunder the excitation of near-infrared light, so that the degradation of the suture line is accelerated. The method has the advantages of simple and safe process, no need of adding an organic solvent,simple operation method, low requirements on equipment, and suitableness for large-scale production and industrialization.

Description

technical field [0001] The invention relates to the field of silk sutures, in particular to an antibacterial silk suture with dual light response functions and a preparation method thereof. Background technique [0002] Surgical-site infection (SSI) remains a widespread problem in modern surgery. According to the Centers for Disease Control and Prevention (CDC), the overall incidence of SSI in the United States is estimated at 2.8%, which equates to 756,000 patients per year. Due to inconsistency between studies, the reported incidence of SSI in European countries ranges from 1.5% to 20%; however, the actual incidence of SSI should be underestimated, suggesting that SSI is also a significant problem in Europe. In my country, SSI is the third leading cause of nosocomial infection, second only to urinary system infection and pneumonia. Data show that SSI accounts for 14-16% of nosocomial infections among inpatients, 38% of nosocomial infections are related to SSI, and 2 / 3 of...

Claims

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Application Information

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IPC IPC(8): A61L17/06A61L17/14A61L17/00
CPCA61L17/005A61L17/06A61L17/145A61L2300/102A61L2300/404
Inventor 杨学涛王小磊曹飞曾斌
Owner NANCHANG UNIV
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