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Gynecological bacteriostatic gel and preparation method of bacteriostatic gel

A gel and gynecological technology, applied in the field of gynecological gel, can solve the problems of short shelf life, expensive traditional Chinese medicine ingredients, waste of resources, etc., and achieve the effect of prolonging the shelf life, improving the bacteriostatic effect, and offsetting the impact.

Pending Publication Date: 2020-08-25
陕西丽仕生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Existing gynecological antibacterial gel products contain many traditional Chinese medicine ingredients, most of which are relatively expensive. Because the shelf life of ordinary gynecological antibacterial gel products is short, after the gynecological antibacterial gel reaches the shelf life, the product It can no longer be sold and used, and the gel produced cannot be sold, which will not only cause losses to the enterprise, but also cause a waste of resources.

Method used

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  • Gynecological bacteriostatic gel and preparation method of bacteriostatic gel

Examples

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Comparison scheme
Effect test

Embodiment 1

[0031] Embodiment 1: A kind of gynecological antibacterial gel, each component of its raw material and its corresponding weight grams are as shown in Table 1, and obtain through following steps preparation:

[0032] Step 1, soak the traditional Chinese medicine in purified water, and decoct for the first time, the weight of the purified water used in the first decoction is 8 times the weight of the traditional Chinese medicine, heat to boiling, keep for 1.5±0.5 hours, filter Obtain the first decoction liquid and filter residue, add purified water to the filter residue for the second decoction, the weight of the purified water used for the second decoction is 6 times the sum of the weight of traditional Chinese medicine, heat to boiling, and keep 1 ± 0.5 hour, filter to obtain the decoction for the second time, and combine the decoction for two times;

[0033]Step 2: Concentrate the combined decoction liquid to obtain an extract 1 with a relative density of 1.10-1.20 at 60° C.,...

Embodiment 2-3

[0037] Example 2-3: A gynecological antibacterial gel, which is different from Example 1 in that its raw material components and their corresponding weight grams are shown in Table 1.

[0038] Each raw material and its weight grams in table 1 embodiment 1-3

[0039] components Example 1 Example 2 Example 3 ice flakes 5 7 3 Lysozyme 0.35 0.5 0.5 glycerin 10 12 8 carbomer 15 10 20 twain 10 9 11 Ethylparaben 3 4 2 Sophora flavescens 50 40 60 cork 50 60 40 angelica 30 20 40 Cnidium 50 60 40 Galla 30 20 40 Cuscuta 50 60 40 aloe vera 50 40 60 blood 20 30 10 safflower 30 20 40 cranberry fruit 50 60 40

Embodiment 4

[0040] Embodiment 4: A kind of gynecological antibacterial gel, the difference from Example 1 is that step four includes the following steps, first dissolving borneol and ethylparaben with an appropriate amount of ethanol and then adding Tween to obtain a mixture, and the mixture , lysozyme, glycerin and extract 2 were added to the gel matrix, stirred after mixing, added purified water to make up to 1000 parts, added dropwise an alkaline pH regulator until the pH was 6.5, stirred and mixed evenly, and obtained a gynecological antibacterial gel. In this embodiment, the alkaline pH regulator is triethanolamine.

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Abstract

The invention discloses a gynecological bacteriostatic gel and a preparation method of the gynecological bacteriostatic gel, and relates to the technical field of gynecological gel. The main technicalpoints of the gynecological gel are that the raw materails of the gynecological bacteriostatic gel comprise traditional Chinese medicine and auxiliary materials; the auxiliary materials comprise thefollowing components in parts by weight: 3-7 parts of borneol, 0.5-0.5 part of lysozyme, 8-12 parts of glycerin, 10-20 parts of Crabomer, 9-11 parts of Tween, 2-4 parts of ethyl paraben, and purifiedwater, using purified water to make up to 1000 parts of gynecological bacteriostatic gel; and the traditional Chinese medicine comprises the following components in parts by weight: 40-60 parts of sophora flavescens, 40-60 parts of phellodendron amurense, 20-40 parts of Chinese angelica, 40-60 parts of cnidium, 20-40 parts of galla chinensis, 40-60 parts of Chinese dodder seeds, 40-60 parts of aloe, 10-30 parts of sangusis draconis, 20-40 parts of safflower, and 40-60 parts of cranberry fruit. The gynecological bacteriostatic gel in the invention has the advantages of prolonging the shelf lifeof the gynecological bacteriostatic gel.

Description

technical field [0001] The invention relates to the technical field of gynecological gel, more specifically, it relates to a gynecological antibacterial gel and a preparation method thereof. Background technique [0002] Gynecological antibacterial gel is a kind of gynecological medicine, which is used for the treatment of various gynecological vaginitis and cervicitis, including: bacterial vaginosis, trichomonal vaginitis, mixed vaginitis, gonococcal infection, chronic cervicitis, It has anti-inflammatory, bactericidal and antipruritic effects. It has obvious inhibitory effect on the growth of Staphylococcus aureus, Escherichia coli, Neisseria gonorrhoeae, Candida albicans and other pathogenic microorganisms. [0003] Existing gynecological antibacterial gel products contain many traditional Chinese medicine ingredients, most of which are relatively expensive. Because the shelf life of ordinary gynecological antibacterial gel products is short, after the gynecological anti...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/47A61K36/896A61K36/889A61K9/06A61K47/42A61K47/18A61K47/12A61P15/00A61P15/02A61P31/04A61P33/02A61K31/045
CPCA61K38/47A61K36/489A61K36/756A61K36/232A61K36/234A61K35/64A61K36/39A61K36/43A61K36/896A61K36/886A61K36/889A61K36/286A61K36/45A61K31/045A61K9/06A61K9/0034A61K47/42A61K47/18A61K47/12A61P15/00A61P15/02A61P31/04A61P33/02A61K2236/331A61K2236/39A61K2236/53A61K2300/00
Inventor 吕晓丽
Owner 陕西丽仕生物科技有限公司
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