Scuticociliatid ciliate resistant pharmaceutical composition and preparation method thereof

A technology of shield ciliate and composition, which is applied in the field of anti-shield ciliate pharmaceutical compositions, can solve problems such as pollution of marine environment, and achieve the effects of reducing mortality, obvious killing effect, and excellent decontamination.

Active Publication Date: 2020-09-01
BEIJING CENT BIOLOGY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the long-term use of pesticides and chemical drugs to treat shield ciliates not only pollutes the marine environment, but also becomes a green trade barrier for the export of aquatic products. Therefore, it is urgent to find new, safe and environmentally friendly insecticides.

Method used

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  • Scuticociliatid ciliate resistant pharmaceutical composition and preparation method thereof
  • Scuticociliatid ciliate resistant pharmaceutical composition and preparation method thereof
  • Scuticociliatid ciliate resistant pharmaceutical composition and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0050] Example 1: Preparation of Drosera powder: Take 230g of Drosera medicinal material, pulverize it, and pass it through a 200-mesh sieve.

[0051] The usage and dosage of embodiment 1: above-mentioned powder is mixed in the 200 kg feed, feeds by daily food intake.

Embodiment 2

[0052] Example 2: Preparation of fatty alcohol polyoxyethylene ether sodium sulfate (AES) liquid preparation: Take 4 g of fatty alcohol polyoxyethylene ether sodium sulfate (AES), add 200 mL of food grade 95% ethanol, mix well, and obtain it.

[0053] Usage and dosage of embodiment 2: get embodiment 2 extract 1L, splash in 2000kg seawater, carry out the medicated bath that suffers from shield ciliate disease turbot, every day medicated bath 30 minutes, continuous medicated bath 5-7 days.

Embodiment 3

[0054] Example 3: Preparation of sundew liquid preparation: Take 200 g of sundew medicinal material, crush it, add 10 times the amount of food-grade 95% ethanol, shake it on a shaker, soak and extract for 5 hours.

[0055] Usage and dosage of embodiment 3: get embodiment 3 extract 1L, splash in 2000kg seawater, carry out the medicated bath that suffers from shield ciliate disease turbot, every day medicated bath 30 minutes, continuous medicated bath 5-7 days.

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Abstract

The invention provides a scuticociliatid ciliate resistant pharmaceutical composition and a preparation method thereof. The pharmaceutical composition is prepared from the following raw materials in parts by weight: 2-3 parts of sundew, 20-30 parts of food-grade ethanol with a concentration of 95%, and 0.3-0.6 part of fatty alcohol polyoxyethylene ether sodium sulfate. The preparation method comprises the following steps: taking 2-3 parts by weight of sundew, crushing sundew, putting crushed sundew into the upper part of a reaction kettle, adding 20-30 parts by weight of food-grade ethanol with a concentration of 95%, stirring and extracting the raw materials for 5 hours to obtain an extract, adding 0.3-0.6 part by weight of fatty alcohol polyoxyethylene ether sodium sulfate into the extract obtained in S1, uniformly mixing to obtain a mixed solution; adding 1000 parts of a turbot feed into the lower part of the reaction kettle, mixing the sundew residues obtained after extraction in S1 with a turbot feed, and fully stirring for 0.5 h. The pharmaceutical composition has the advantages that the toxicity to turbots is small, the pharmaceutical composition is environmentally friendly,the scuticociliatid ciliate infection rate is effectively reduced, and the extract and a mixed feed can be produced at the same time.

Description

technical field [0001] The present invention relates to the technical field of anti-shield ciliate pharmaceutical composition, in particular to an anti-shield ciliate pharmaceutical composition and a preparation method thereof. Background technique [0002] Turbot, also known as turbot, is naturally distributed in the European coast from the east to the northeast of the Atlantic Ocean, and lives as a bottom dweller. Since it was introduced into our country, it has created good economic benefits, and its artificial breeding has become one of the important pillar industries of marine aquaculture in our country. However, as the breeding density of turbot continues to increase and the research on disease control lags behind, various breeding diseases are coming one after another. Among various aquaculture diseases, the parasitic diseases caused by shield ciliates, Cryptocaryon, trichotillomantis and flagellates have caused great losses to the turbot aquaculture industry, and th...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/185A61K9/00A61K47/20A61P33/02A23K50/80A23K20/10B01J19/18A61K31/795
CPCA61K36/185A61K31/795A61K9/0014A61K9/0053A61K47/20A61P33/02A23K50/80A23K20/10B01J19/18B01J19/0053B01J19/006B01J19/0066A61K2236/333A61K2300/00Y02A50/30Y02A40/81
Inventor 李福元韩俊国严永郭智伟程安达王心喜王秀敏
Owner BEIJING CENT BIOLOGY
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