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Whitening composition and preparation method thereof

A composition and whitening technology, which can be used in pharmaceutical formulations, cosmetic preparations, dressing preparations, etc., and can solve the problem of single types of whitening active ingredients

Active Publication Date: 2020-11-03
HARMEN LEIMOGAOSHI ESSENCE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The technical problem to be solved by the present invention is the shortcoming that the types of existing whitening active ingredients are relatively single. Therefore, the present invention provides a whitening composition and its preparation method

Method used

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  • Whitening composition and preparation method thereof
  • Whitening composition and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0224] In terms of mass percentage:

[0225] Stir and dissolve 0.5% phenylethylresorcinol, 1% caprylic capric triglyceride, 1% sodium stearoyl lactylate, and 0.1% butyl hydroxyanisole in a water bath at 40°C to obtain an oil phase ,spare;

[0226] Stir and dissolve 5% carnosine, 10% nicotinamide, 30% white truffle extract, 10% Morus alba extract and 22.4% water in a water bath at a temperature of 40°C to obtain an aqueous phase for later use;

[0227] After the oil phase and the water phase were obtained, the oil phase was added dropwise to the water phase at a rate of 2 drops / second in a water bath at 40°C. During the dropping process, the stirring rate was controlled at 600 rpm. After the mixing was completed, 10% ethyl alcohol was added. Oxydiglycol and 10% glycerin were emulsified under high-speed shear at 5000 rpm for 10 min to make a micron-sized dispersion.

[0228] The micron-sized dispersion was subjected to high-pressure homogenization treatment at a pressure of 16...

Embodiment 2

[0231] In terms of mass percentage:

[0232] 5% phenylethyl resorcinol, 5% isopropyl palmitate, 5% PEG-8 caprylic / capric glycerides, 10% tribehenyl PEG-20 esters, 0.3% butylated hydroxytoluene at temperature Stir and dissolve in a water bath at 50°C to obtain an oil phase for later use;

[0233] Stir and dissolve 2% carnosine, 20% nicotinamide, 10% white truffle extract, 0.5% Morus alba extract and 27.2% water in a water bath at a temperature of 50°C to obtain an aqueous phase for later use;

[0234] After the oil phase and water phase were obtained, the oil phase was added dropwise to the water phase at a rate of 6 drops / second in a water bath at 50°C, and the stirring rate was controlled at 500 rpm during the dropping process. After mixing, 5% propylene glycol was added , 10% octyldodecanol, high-speed shear emulsification at 6000 rpm for 3 min to make a micron-sized dispersion.

[0235] The micron-scale dispersion was subjected to high-pressure homogenization treatment at...

Embodiment 3

[0238] In terms of mass percentage:

[0239] 12% phenylethyl resorcinol, 15% isopropyl palmitate, 5% polyoxyethylene sorbitan fatty acid ester, 10% polyoxyethylene hydrogenated castor oil, 5% cocoyl glucoside, 2 % Vitamin E acetate was stirred and dissolved in a water bath at a temperature of 55°C to obtain an oil phase for subsequent use;

[0240] Stir and dissolve 0.8% carnosine, 6% nicotinamide, 5% white truffle extract, 10% Morus alba extract and 19.2% water in a water bath at a temperature of 55°C to obtain an aqueous phase for later use;

[0241] After the oil phase and the water phase are obtained, add the oil phase to the water phase at a rate of 5 drops / second in a water bath at 55°C. During the dropping process, the stirring rate is controlled at 900 rpm. After the mixing is completed, add 10% PPG -26-butanol-26, high-speed shear emulsification at 7000 rpm for 6 min to make a micron-scale dispersion.

[0242] The micron-scale dispersion was subjected to high-pressu...

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Abstract

The invention discloses a whitening composition and a preparation method thereof. The preparation method of the whitening composition, provided by the invention, comprises the following steps of (1) adding an oil phase into a water phase to obtain a mixture A; (2) adding 1-20 wt.% of a co-emulsifier into the mixture A prepared in the step (1) to obtain a mixture B; (3) shearing and emulsifying themixture B prepared in the step (2) to obtain a dispersion C; and (4) performing high-pressure homogenization or high-speed microjet on the dispersion C prepared in the step (3) to obtain the whitening composition. The wt.% refers to the percentage by mass of a certain component relative to all components in the whitening composition. The whitening composition has the advantages of better encapsulation efficiency, better melanin inhibition effect, better skin permeability and retentivity, and lower toxicity, and the components in the whitening composition have a synergistic effect.

Description

technical field [0001] The invention relates to a whitening composition and a preparation method thereof. Background technique [0002] Whitening has always been the eternal pursuit of oriental women, and there are endless whitening products on the market. [0003] However, there are many disadvantages when whitening active ingredients are directly added to the skin care system: (1) most of the whitening active ingredients are poor in stability, and are prone to oxidative deterioration and discoloration during the product placement process and lose their whitening effect; (2) some whitening active ingredients will also (3) Due to the skin's own barrier, it is difficult for whitening active ingredients to penetrate the stratum corneum and enter the basal layer of the skin, greatly reducing the whitening effect. [0004] In order to solve the application and skin absorption problems of whitening active ingredients, the researchers carried out nano-encapsulation of one or more...

Claims

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Application Information

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IPC IPC(8): A61K8/34A61K8/365A61K8/37A61K8/60A61K8/64A61K8/67A61K8/86A61K8/92A61K8/9767A61K8/9789A61Q19/02
CPCA61K8/34A61K8/342A61K8/345A61K8/347A61K8/365A61K8/37A61K8/375A61K8/604A61K8/64A61K8/675A61K8/678A61K8/86A61K8/922A61K2800/5922A61Q19/02A61K8/9767A61K8/9789
Inventor 劳树权王银娟周康夫
Owner HARMEN LEIMOGAOSHI ESSENCE
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