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Novel coronavirus disinfectant derived from biomass active ingredients and preparation method thereof

A coronavirus and disinfectant technology, applied in the field of disinfectants to inactivate the new coronavirus COVID-19, can solve the problems of high safety requirements for use and storage, irritation and corrosiveness, animal and plant health risks, etc. Eco-environmental benefits, low cost, and significant killing effect

Pending Publication Date: 2020-11-10
FUDAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The above types of disinfectants are currently widely used, and they are likely to cause various environmental safety problems while spraying a large number of public areas in various cities.
Because alcohol is flammable, its use and storage safety requirements are high; other conventional disinfectants are irritating and corrosive to human skin and respiratory tract, and some are not easy to decompose in the environment, and are easy to remain. Plant health is potentially at risk

Method used

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  • Novel coronavirus disinfectant derived from biomass active ingredients and preparation method thereof
  • Novel coronavirus disinfectant derived from biomass active ingredients and preparation method thereof
  • Novel coronavirus disinfectant derived from biomass active ingredients and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Sawdust and water were mixed in the reactor according to a certain solid-to-liquid ratio (1:13), sealed and placed on the heater, and the temperature was raised to 330 °C at a rate of 5 °C / min and maintained for 1 hour. After the reaction was completed, Cool to room temperature. The obtained solid-liquid mixture is separated, and filtered through a 0.45 μm filter membrane to obtain a plant component extract, that is, a disinfectant. After diluting the disinfectant to different multiples, add it to the Sars-Cov-2 genetic material nucleic acid synthesized by the HiScribe T7 kit, react at room temperature for 30 minutes, and use the new coronavirus nucleic acid extraction-free on-site rapid detection system to measure the nucleic acid reaction. Investigate the effect of disinfectants on novel coronavirus. The results showed that the disinfectant extracted from sawdust was negative for the nucleic acid of the new coronavirus, indicating that the disinfectant had a signific...

Embodiment 2

[0022] Wheat straw and water were mixed in the reactor according to a certain solid-to-liquid ratio (1:13), sealed and placed on the heater, and the temperature was raised to 330 °C at a rate of 5 °C / min, and maintained for 1 hour, until the end of the reaction After cooling to room temperature. The obtained solid-liquid mixture is separated, and filtered through a 0.45 μm filter membrane to obtain a plant component extract, that is, a disinfectant. After diluting the disinfectant to different multiples, add it to the Sars-Cov-2 genetic material nucleic acid synthesized by the HiScribe T7 kit, incubate at room temperature for 30 minutes, and use the new coronavirus nucleic acid extraction-free on-site rapid detection system to measure the nucleic acid reaction. Investigate the effect of disinfectants on novel coronavirus. The results showed that the disinfectant extracted from wheat straw was negative for the nucleic acid reaction of the new coronavirus, indicating that the d...

Embodiment 3

[0024] Sawdust and water were mixed in the reactor according to a certain solid-to-liquid ratio (1:13), sealed and placed on the heater, and the temperature was raised to 330 °C at a rate of 5 °C / min and maintained for 1 hour. After the reaction was completed, Cool to room temperature. The obtained solid-liquid mixture is separated, and filtered through a 0.45 μm filter membrane to obtain a plant component extract, that is, a disinfectant. Add the biological disinfectant to the recombinant spike protein of SARS-COV-2 virus, incubate at room temperature for 30 minutes, use fluorescent lateral flow test paper and supporting equipment to detect protein activity, and investigate the killing effect of the disinfectant on the new coronavirus . The results show( figure 2 ), the degradation rate of the virus protein reached 85%.

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Abstract

The invention belongs to the technical field of disinfectants, and particularly relates to a novel coronavirus COVID-19 disinfectant derived from biomass active ingredients and a preparation method ofthe novel coronavirus COVID-19 disinfectant. Biomass (mainly such as one or a mixture of more of sawdust, crop straw, rice husk, corncob, bagasse, bean dregs, rape seed cakes, microalgae, walnut shells, salix psammophila, bamboos, tree leaves, tree barks and fruit peels) is adopted as a raw material, and the novel coronavirus COVID-19 disinfectant is prepared through a thermochemical extraction technology. The novel disinfectant has the advantages of being environmentally friendly, low in toxicity, efficient and environmentally friendly, can be applied to the environment and objects to effectively kill the novel coronavirus COVID-19, and prevents virus propagation.

Description

technical field [0001] The invention belongs to the technical field of disinfectants, in particular to a disinfectant for inactivating novel coronavirus COVID-19. Background technique [0002] In the past two decades, the emergence of epidemic viruses and continuously evolving strains have posed a huge threat to human health and social development. Since the end of 2019, the new coronavirus COVID-19 has swept the world. The outbreak of this outbreak has been called a global "pandemic" by the World Health Organization (WHO), and more than 200 countries and regions around the world have been affected. [0003] The diagnosis and treatment plan for novel coronavirus pneumonia points out that droplet transmission, contact transmission (contact with infected inanimate objects), aerosol transmission and patient's excrement transmission are the main modes of transmission of the COVID-19 virus. Among them, the content of contact transmission is extensive, such as touching public tra...

Claims

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Application Information

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IPC IPC(8): A01N65/44A01N61/00A01P1/00
CPCA01N61/00A01N65/00A01N65/44
Inventor 朱向东张士成隋国栋商华赵望张童罗洁文
Owner FUDAN UNIV
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