Oral guided bone regeneration and repair system and preparation method

Abstract

The invention provides an oral guided bone regeneration and repair system and a preparation method thereof, and belongs to the technical field of oral implantation. The oral guided bone regeneration and repair system comprises a bone filling support, a barrier film and bone cell growth guiding fibers, wherein the barrier film comprises a first arc-shaped surface and a second arc-shaped surface which are oppositely arranged in the thickness direction of the barrier film, and the first arc-shaped surface corresponds to a bone defect area of an oral cavity to be repaired; the bone filling supportis arranged on the first arc-shaped surface, and the bone cell growth guiding fibers are arranged on the bone filling support in a winding mode according to the preset orientation so as to guide directional growth of bone cells in the bone defect area. The oral guided regeneration and repair system provides enough space for growth of bone cells, has the capacity of resisting bacterium breeding and the characteristic of being completely degradable and absorbable, does not need to be taken out through a secondary operation, can also accelerate the bone growth speed, can shorten the treatment time of an oral cavity bone defect patient, and can improve the postoperative recovery probability of implantation.

Description

technical field [0001] The invention belongs to the technical field of oral implantation, and in particular relates to an oral guided bone regeneration repair system and a preparation method of the oral guided bone regeneration repair system. Background technique [0002] To meet the needs of different patients, oral implants are more and more widely used, but in practical applications, patients often encounter problems such as insufficient bone mass and poor implant retention. According to the characteristics of bone and soft tissue growth, guided bone regeneration (GBR) technology is often used for bone augmentation. However, in the process of bone tissue repair, the growth rate of fibroblasts is much greater than that of osteocytes. In order to prevent this layer of soft tissue from occupying the growth space of bone tissue and resulting in insufficient bone formation, it is necessary to implant a layer of barrier membrane to block the growth of fibroblasts into the bone...

AI Technical Summary

Problems solved by technology

Its shortcoming is that although the micro-nano fibers prepared by electrospinning technology have a three-dimensional bionic extracellular matrix structure suitable for cell growth, they have high chemical activity due to their large specific surface area. The faster decomposition rate will cause the stimulation of acidic products, so as to cause irritation to the surrounding tissues and even induce inflammation, which is harmful to the treatment of oral bone tissue.

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