A kind of antipruritic effect composition and its preparation method and application
A composition and anti-pruritic technology, applied in the directions of drug combination, medical preparations containing active ingredients, pharmaceutical formulations, etc., to achieve the effects of excellent moisturizing, strengthening skin barrier and improving skin comfort
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Embodiment 1
[0053] Embodiment 1: A kind of preparation method of antipruritic effect composition, it is characterized in that: adopt following steps:
[0054] A. Weigh 2 parts of mussel extract, 7 parts of loquat leaf extract, 5 parts of saffron extract, 5 parts of tocotrienol, 3 parts of sclareolide, and pantethein by weight ratio 3 parts of calcium carbonate, 30 parts of β-cyclodextrin;
[0055] B. Mix the mussel extract, loquat leaf extract, saffron extract, tocotrienol, sclareolactone, and pantethein calcium calcium pantetheine sulfonate weighed in step A, and fully dissolve in the volume fraction 40% ethanol aqueous solution, then add the β-cyclodextrin weighed in step A, stir at 400 rpm for 20 minutes, and spray dry to obtain an anti-itching effect composition.
Embodiment 2
[0056] Embodiment 2: a kind of preparation method of antipruritic effect composition, it is characterized in that: adopt following steps:
[0057] A. Weigh 1 part of mussel extract, 2 parts of loquat leaf extract, 2 parts of saffron extract, 2 parts of tocotrienol, 1 part of sclareolide, and pantethein by weight ratio Calcium acid 1 part, β-cyclodextrin 20 parts;
[0058] B. Mix the mussel extract, loquat leaf extract, saffron extract, tocotrienol, sclareolactone, and pantethein calcium calcium pantetheine sulfonate weighed in step A, and fully dissolve in the volume fraction 20% ethanol aqueous solution, then add the β-cyclodextrin weighed in step A, stir at 300 rpm for 40 minutes, and spray dry to obtain an anti-itching effect composition.
Embodiment 3
[0059] Embodiment 3: a kind of preparation method of antipruritic effect composition, it is characterized in that: adopt following steps:
[0060] A. Weigh 5 parts of mussel extract, 5 parts of loquat leaf extract, 7 parts of saffron extract, 7 parts of tocotrienol, 2 parts of sclareolide, and pantethein by weight ratio Calcium acid 2 parts, β-cyclodextrin 25 parts;
[0061] B. Mix the mussel extract, loquat leaf extract, saffron extract, tocotrienol, sclareolactone, and pantethein calcium calcium pantetheine sulfonate weighed in step A, and fully dissolve in the volume fraction 30% ethanol aqueous solution, then add the β-cyclodextrin weighed in step A, stir at 350 rpm for 30 minutes, and spray dry to obtain an anti-itching effect composition.
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