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Antibacterial treatment method of antibacterial three-dimensional porous bone implant material

A bone implant material, three-dimensional porous technology, applied in the field of bone implant production technology, can solve the problems of reducing antibacterial properties of bone implants, stress shielding effect, implant instability, etc., to avoid the antibacterial properties of the base material , Improve stability, reduce deformation and looseness

Inactive Publication Date: 2021-01-22
李炳亮
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] With the improvement of medical technology and the development of economic level, various implants such as titanium and titanium alloys used for orthopedic replacement, orthopedics, and fixation are more and more used in surgery. In recent years, porous bone implant materials , such as 3D printing titanium alloy and porous tantalum metal, have also been commercially applied clinically as bone implant materials, achieving the purpose of solving the pain of patients and restoring function. Putting implant materials in the human body is a traumatic Surgery, postoperative complications are also prone to occur, especially the related infection caused by implants has become the most serious and even catastrophic complication, especially in open fractures and joint revisions, which often require multiple surgical debridements. Trauma, removal of internal fixation or prosthesis, resulting in operation failure, increased costs, and increased disability of patients
[0003] The traditional method of improving the antibacterial properties of bone implants has the following disadvantages. The traditional method of improving the antibacterial properties of bone implants is to activate the surface of the implant, and then introduce antibacterial ions into the surface of the implant to form an antibacterial film. In order to achieve the antibacterial effect, on the surface of clinical application, during the long-term implantation process of metal materials, due to the large difference between the elastic modulus and human bones, it is easy to produce stress shielding effect, resulting in unstable implants, deformation and loosening. This leads to severe wear, and the metal ions and particles produced by the wear are potentially toxic, which will easily reduce the antibacterial properties of bone implants during long-term use. Therefore, we propose an antibacterial three-dimensional porous bone implant material. Approach

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] An antibacterial treatment method for antibacterial three-dimensional porous bone implant materials, including the following production materials and processing equipment: porous bone implant substrates, pickling pools, ultrasonic cleaning machines, grinding and polishing machines, vacuum furnaces and multi-arc ion coating machines, Including the following steps:

[0019] S1. Base material grinding and polishing: select a suitable porous bone implant base material, and use a grinding and polishing machine to grind and polish the surface of the base material;

[0020] S2. Substrate pickling: After the surface of the substrate is ground and polished, it is sent to the pickling pool. The substrate is initially pickled by the pickling solution in the pickling pool, and the substrate is treated with deionized water after pickling. to clean,

[0021] S3. Ultrasonic cleaning of the base material: put the cleaned base material into the ultrasonic cleaning machine for ultrasoni...

Embodiment 2

[0028] An antibacterial treatment method for antibacterial three-dimensional porous bone implant materials, including the following production materials and processing equipment: porous bone implant substrates, pickling pools, ultrasonic cleaning machines, grinding and polishing machines, vacuum furnaces and multi-arc ion coating machines, Including the following steps:

[0029] S1. Base material grinding and polishing: select a suitable porous bone implant base material, and use a grinding and polishing machine to grind and polish the surface of the base material;

[0030] S2. Substrate pickling: After the surface of the substrate is ground and polished, it is sent to the pickling pool. The substrate is initially pickled by the pickling solution in the pickling pool, and the substrate is treated with deionized water after pickling. to clean,

[0031] S3. Ultrasonic cleaning of the base material: put the cleaned base material into the ultrasonic cleaning machine for ultrasoni...

Embodiment 3

[0038] An antibacterial treatment method for antibacterial three-dimensional porous bone implant materials, including the following production materials and processing equipment: porous bone implant substrates, pickling pools, ultrasonic cleaning machines, grinding and polishing machines, vacuum furnaces and multi-arc ion coating machines, Including the following steps:

[0039] S1. Base material grinding and polishing: select a suitable porous bone implant base material, and use a grinding and polishing machine to grind and polish the surface of the base material;

[0040] S2. Substrate pickling: After the surface of the substrate is ground and polished, it is sent to the pickling pool. The substrate is initially pickled by the pickling solution in the pickling pool, and the substrate is treated with deionized water after pickling. to clean,

[0041] S3. Ultrasonic cleaning of the base material: put the cleaned base material into the ultrasonic cleaning machine for ultrasoni...

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Abstract

The invention discloses an antibacterial treatment method of an antibacterial three-dimensional porous bone implant material. The method comprises the following production raw materials and processingequipment of a porous bone implant base material, a pickling tank, an ultrasonic cleaning machine, a grinding and polishing machine, a vacuum furnace and a multi-arc ion plating machine. Compared with other production technologies, the technology is mature, the glow discharge principle is adopted, ions formed by collision of particles accelerated at an electric field with nitrogen-containing gasmolecules and atoms are adsorbed on the surface of the base material, the surface of the base material is modified, the surface of the base material is coated with a film through the multi-arc ion plating machine, the surface of the base material is coated with a layer of TiN, and nitrogen ions are injected into the surface of the base material to modify the base material. The TiN coating is plated on the surface of the base material, and the TiN coating and the base material are matched with each other, so that the abrasion resistance of the base material after implantation is comprehensivelyimproved, the friction coefficient is reduced, metal ions and particles generated due to abrasion in the implantation use process of the base material are reduced, the antibacterial property of the base material is prevented from being lowered by the metal ions, and the antibacterial effect of the base material after implantation is improved from the aspect of reducing base material losses.

Description

technical field [0001] The invention relates to a bone implant production process, and more specifically, relates to an antibacterial treatment method for an antibacterial three-dimensional porous bone implant material. Background technique [0002] With the improvement of medical technology and the development of economic level, various implants such as titanium and titanium alloys used for orthopedic replacement, orthopedics, and fixation are more and more used in surgery. In recent years, porous bone implant materials , such as 3D printing titanium alloy and porous tantalum metal, have also been commercially applied clinically as bone implant materials, achieving the purpose of solving the pain of patients and restoring function. Putting implant materials in the human body is a traumatic Surgery, postoperative complications are also prone to occur, especially the related infection caused by implants has become the most serious and even catastrophic complication, especiall...

Claims

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Application Information

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IPC IPC(8): C23C8/36C23C8/02C23C14/06C23C14/32A61L27/56A61L27/30A61L27/06
CPCA61L27/06A61L27/306A61L27/56A61L2400/18A61L2420/02A61L2430/02C23C8/02C23C8/36C23C14/0641C23C14/325
Inventor 李炳亮
Owner 李炳亮