Polyglycolide copolymer and preparation tehreof
A polyglycolide and copolymer technology, applied in the field of degradable copolymers and its preparation, can solve the problems of poor mechanical and mechanical properties
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Embodiment 1
[0054] Example 1: Polyglycolide (or polyglycolic acid (PGA))
[0055] Glycolide and 0.01 parts by weight of ring-opening polymerization catalyst tin dichloride dihydrate were mixed uniformly at 120° C. for 60 minutes in a prefabricated tank reactor in an amount of 0.01 parts by weight relative to the weight of glycolide.
[0056] The materials in the prefabricated tank reactor were introduced into the polymerization reactor, and reacted at 200° C. and an absolute pressure of 0.1 MPa for 300 minutes. The polymerization reactor is a plug flow reactor, which can be a static mixer, a twin screw device or a horizontal disc reactor.
[0057] The contents of the polymerization reactor were introduced into the optimized reactor at a mixing speed of 200 RPM at 220 °C and an absolute pressure of 50 Pa. The reaction time was 30 minutes. As a result, polyglycolide was produced.
Embodiment 2
[0058] Example 2: Characterization
[0059] 1. Weight average molecular weight and its distribution
[0060] The sample was dissolved in 5 mmol / L sodium trifluoroacetate in hexafluoroisopropanol solution to prepare a 0.05-0.3 wt% (mass fraction) solution. The solution was then filtered through a polytetrafluoroethylene filter with a pore size of 0.4 μm. 20 μL of the filtered solution was added to a gel permeation chromatography (GPC) injector to determine the molecular weight of the sample. Five standard molecular weights of methyl methacrylate with different molecular weights were used for molecular weight calibration.
[0061] 2. Tensile strength test
[0062]The tensile strength is tested according to GB / T1040 1-2006, and the tensile speed is 50mm / min.
[0063] 3. Melt index (MFR) test
[0064] The melt index (MFR) of the copolymer is tested as follows: 1) the copolymer is dried at 105° C. in a vacuum drying oven; 2) the test temperature of the test instrument is set t...
Embodiment 3
[0067] Example 3: Copolymer
[0068] Prepare polyglycolide (PGA), copolymer 1-6 and polylactic acid (PLA) as comparison with polyglycolide described in embodiment 1 and one or more additives, then according to embodiment 2 Characterized by the method described above. Table 1 shows the composition and properties of these copolymers.
[0069] PGA was pelletized at an extrusion temperature of 250°C by putting polyglycolide and 0.06wt% Irganox 168 and 0.03wt% Irganox MD-1025 additives based on the total weight of the copolymer into a twin-screw extruder And prepared. The pellets were dried at 120°C for 4 hours and molded into strips for testing using an injection molding machine at an injection temperature of 250°C and a molding temperature of 100°C. The test results are shown in Table 1.
[0070] Copolymer 1 puts polyglycolide and the Irganox 168 based on the total weight of copolymer 0.06wt%, the Irganox MD-1025 of 0.03wt% and the ADR4368 additive of 0.2wt% into the twin-scr...
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