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Natural plant-derived bacteriostatic composition and application thereof

A technology of natural plants and compositions, applied in the direction of medical preparations containing active ingredients, cosmetic preparations, skin care preparations, etc., can solve the problems of deep color without antiseptic ingredients, poor broad-spectrum antibacterial properties, single application research, etc. , to achieve the effects of reducing the risk of irritation, improving the safety of cosmetics, and simplifying the preparation process

Pending Publication Date: 2021-03-19
JIANGSU NAIQUE BIOLOGICAL ENG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the existing non-preservative compositions have the following defects: the application research on cosmetic antiseptics is relatively single, some non-corrosion components are too dark in color and heavy in raw material taste, and their broad-spectrum antibacterial properties are worse than chemical preservatives, and some may even bring to allergies
The development of raw materials to replace preservatives is a very promising job, but the existing natural preservatives have poor antiseptic properties. The cosmetics industry urgently needs a composition with strong antiseptic properties to replace existing products. meet higher requirements

Method used

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  • Natural plant-derived bacteriostatic composition and application thereof
  • Natural plant-derived bacteriostatic composition and application thereof
  • Natural plant-derived bacteriostatic composition and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] 1. Preparation of Radix Paeoniae Alba extract: Get 1 kg of Radix Paeoniae Alba, add 15 kg of water to soak for 24 hours, then boil and extract for 2 hours, filter to obtain the Radix Paeoniae Alba extract; pass the Radix Paeoniae Alba extract over 2 kg of neutral alumina ( National Medicine Reagent 20002360) column, wash away the residual extract with purified water (5kg) 5 times the weight of the material, elute the neutral alumina column with 95% ethanol (5kg) 5 times the weight of the material, collect the ethanol eluate and decompress Dried to obtain Radix Paeoniae Alba extract 65g, set aside;

[0023] 2. Preparation of Artemisia capillaris extract: Take 1Kg of the clean Artemisia capillaris, add 20kg of water to soak for 24 hours, then boil and extract for 2 hours, filter to obtain Artemisia capillaris extract; take Artemisia capillaris extract and concentrate to 1 time the weight of the medicinal material, adding 1 kg of petroleum ether for extraction twice, conce...

Embodiment 2

[0026] 1. Preparation of Radix Paeoniae Alba extract: Get 1 kg of Radix Paeoniae Alba, add 20 kg of water to soak for 24 hours, then boil and extract for 2 hours, filter to obtain the Radix Paeoniae Alba extract; pass the Radix Paeoniae Alba extract over 3 kg of neutral alumina ( National Medicine Reagent 20002360) column, wash away the residual extract with purified water (4kg) 4 times the weight of the material, elute the neutral alumina column with 95% ethanol (5kg) 5 times the weight of the material, collect the ethanol eluate, concentrate Dried to obtain Radix Paeoniae Alba extract 56.5g, for subsequent use;

[0027] 2. Preparation of Artemisia capillaris extract: Take 1Kg of the clean Artemisia capillaris, add 15kg of water to soak for 24 hours, then boil and extract for 2 hours, filter to obtain Artemisia capillaris extract; take the above-mentioned Artemisia capillaris extract and concentrate to 1 time of the weight of the medicinal material, add 1 kg of petroleum ethe...

Embodiment 3

[0030] 1. Preparation of Radix Paeoniae Alba extract: Get 1 kg of Radix Paeoniae Alba, add 15 kg of water to soak for 24 hours, then boil and extract for 2 hours, filter to obtain the Radix Paeoniae Alba extract; pass the Radix Paeoniae Alba extract over 3 kg of neutral alumina ( National Medicine Reagent 20002360) column, wash away the residual extract with purified water (3kg) with a weight of 3 materials, and elute the neutral alumina column with 95% ethanol (4kg) 4 times the weight of materials, collect the ethanol eluate, concentrate and dry , obtain Radix Paeoniae Alba extract 58g, set aside;

[0031] 2. Preparation of Artemisia capillaris extract: Take 1Kg of the clean Artemisia capillaris, add 20kg of water to soak for 24 hours, then boil and extract for 2 hours, filter to obtain Artemisia capillaris extract; take the above Artemisia capillaris extract Concentrate to 1 time of the weight of the medicinal material, add 1 kg of medicinal material to extract twice with pe...

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Abstract

The invention discloses a natural plant-derived bacteriostatic composition and application thereof. The natural plant-derived bacteriostatic composition comprises a white paeony root extract and an artemisia capillaris extract, wherein the mass ratio of the white paeony root extract to the artemisia capillaries extract is (65-80): (20-35). The bacteriostatic composition disclosed by the inventionhas a synergistic bacteriostatic effect, is simple in preparation process and good in water solubility, can replace chemical preservatives, is added into various emulsion cream skin care product units, is mild and non-irritant, and is suitable for various crowds.

Description

technical field [0001] The invention relates to the field of daily cosmetics, in particular to a cosmetic auxiliary agent, in particular to a natural plant-derived bacteriostatic composition and its application. Background technique [0002] Cosmetics usually contain rich nutrients, which are especially suitable for the growth of microorganisms. The purpose of adding preservatives to cosmetics is to inhibit the growth and generation of bacteria, avoid deterioration of cosmetics and maintain freshness and persistence. Most of the preservatives used in cosmetics are artificial synthetic substances that are simple to manufacture, low in unit price and easy to mass-produce. Representative of the above-mentioned preservatives are: methyl benzoate, ethyl p-hydroxybenzoate, propyl p-hydroxybenzoate, butyl p-hydroxybenzoate, etc. and quaternary ammonium salt-15, imidazolidinyl urea, bis(hydroxybenzoate) Methyl) imidazolidinyl urea, phenoxyethanol, benzalkonium chloride, triclosan a...

Claims

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Application Information

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IPC IPC(8): A61K8/9789A61Q19/00
CPCA61K8/9789A61Q19/00A61K2800/524A61K2800/72
Inventor 王明月魏元刚
Owner JIANGSU NAIQUE BIOLOGICAL ENG
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