Artemisia flavonoids and its preparation method and application
A technology of flavonoids and artemisinin, applied in the direction of active ingredients of heterocyclic compounds, cosmetic preparations, applications, etc., can solve the problems of biological activity to be strengthened, achieve high effective utilization rate of raw materials, increase utilization rate, and inhibit tyramine Effect of Acidase Activity
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment 1
[0072] A method of preparation of oxette flavonoid compound, including the following specific steps:
[0073] 1) Add the above 32L water to 2.5kg of oxette medicinal materials, and the first decoction filter is carried out in a 500L sandwich pot, and the boiling temperature is 180 ° C, decoction time is 120min, stir all 20 minutes, filtered through 100 mesh screen It obtains the segmented I and the liquid I. The second decoction filter is added to the above-mentioned drug residue I, and the boiling temperature is 180 ° C, decoction time is 30 min, stirred once every 20 minutes, filtered through 100 mesh screen It is obtained from the segments II and the drug solution II; discard the segments II, and then mix the above liquid II and the above liquid solution II together to obtain the above filtration liquid;
[0074] 2) The above-described filtration liquid was stirred and concentrated, and the density of the above filtration liquid was detected. When the density of the above-descr...
Embodiment 2
[0086] A method of preparation of oxette flavonoid compound, including the following specific steps:
[0087] 1) Crushing 2.5 kg of oxinin medicinal materials to over 100 mesh sieves, then adding a volume concentration of 85% to Niu Nikin, and the material is 1 g: 150 mL, and then at a frequency of 50 kHz, the power is 300W. Ultrasound extraction 3 times, single extraction time is 45min, combined with each extraction filtrate, recover ethanol under reduced pressure, to obtain a concentrated liquid, then place the concentrate in -80 ° C, refrigerate, to obtain ethanol of oxette medicinal Extract;
[0088] 2) Take the ethanol extract of the catasil medicinal material to dissolve with water, then extract 4 times with ethyl acetate and polyethylene glycol mixed solvent, combined with the extract, and reduce the solvent at 50 ° C, the resulting bold material is spare; the above acetic acid The volume ratio of ethyl acetate and polyethylene glycol in ethyl ester and polyethylene glycol ...
Embodiment 3
[0092] Structural identification of Niu Tenten flavonoids: Comprehensive IR, MS, 1 H-NMR, 13 C-NMR and other techniques analyze the material structure. The experimental sample is the oxinous flavonoid compound of the octhilica.
[0093] Measurement results: Niu Tenten flavonoid compound: light yellow crystallization, excimer ion peak 415.4125 [M + H] + Combine 1 H-NMR and 13 C-NMR infers its molecular formula C 22 Hide 22 O 8 . Infrared map (IR): 3423.4cm -1 A absorption peak shows a hydroxyl group, 2015.3cm -1 A absorption peak is shown in -c = C- existence, 1703.1cm -1 The absorption peak shows that there is a benzene ring, 1146.5cm -1 The absorption peak is displayed in C-O existence.
[0094] use 1 H-NMR and 13 The C-NMR spectrum is abbreviated with hydrogen and carbon signals, and the signal belongs are as follows:
[0095] 1 H-NMR (DMSO-D 6 500MHz, PPM): Δ7.03 (1H, S, J = 1.5 Hz, CH), 6.81 (1H, S, J = 7.5 Hz, CH), 6.81 (1H, S, J = 7.5, 1.5 Hz, CH ), 6.14 (1H, S, J = 1.0 Hz, ...
PUM
Login to View More Abstract
Description
Claims
Application Information
Login to View More