Substance for improving lethality of immune cells as well as preparation and application of substance

A technology of immune cells and lethality, applied in the field of medicine, can solve problems such as deficiency
CN112618718APending Publication Date: 2021-04-09HANDAN PHARMA
4 Cites 0 Cited by

Patent Information

Authority / Receiving Office
CN ยท China
Current Assignee / Owner
HANDAN PHARMA
Publication Date
2021-04-09

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

The invention discloses a substance for improving the lethality of immune cells as well as a preparation and application of the substance. The substance for improving the lethality of immune cells comprises one or more of berberine, benzoyloxypaeoniflorin, methylophiopogonone A, canadin(tetrahydroberberine), leucoside(kaempferol 3-O-sambubioside), cheilanthifoline, bucuculline, sibirioside A, harpagide, dendrobine, coptisine hydrochloride, coptisine, norisoboldine, ginsenoside Rg3, 3,5-Dicaffeoyl quinic acid, L-arginine, 3-O-feruloylquinic acid, lucidone, atractyloside A, ginsenoside Rh3, Cholan-24-oic acid, oleuropein, parishin A, parishin B, p-hydroxyphenylethyl trans-ferulate, Palbinone, pseudo-ginsenoside RT1, pimpinellin, 4-hydroxybenzoic acid, Eburicoic acid, alismoxide and alpha-cyperone. According to the substance disclosed by the invention, immunity-related genes such as CD46, MUC16, TGF-beta and the like and GAST and SS18 are selected as direct or indirect regulation and control target genes from genes of which the expression quantity is obviously changed in transcriptome analysis data.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The invention belongs to the technical field of medicine, and in particular relates to a substance for improving the lethality of immune cells, its preparation and application. Background technique

[0002] Chronic atrophic gastritis (CAG) is characterized by atrophy of gastric mucosal epithelium and glandular tissue, reduction in the number of mucosal cells, thinning of gastric mucosa, thickening of the submucosal layer, or accompanied by pyloric gland metaplasia and intestinal gland metaplasia, or abnormal Chronic digestive disease characterized by typical hyperplasia. my country is an area with a high incidence of gastric cancer, and the occurrence of most gastric cancer follows the gastric cancer occurrence model proposed by Correa cascade reaction: normal gastric mucosa - superficial gastritis - atrophic gastritis - small intestine-type intestinal metaplasia - large intestine-type intestinal metaplasia - Dysplasia (moderate to severe) - gastric ca...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More