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Compound lysozyme oral spray and preparation method thereof

A technology of oral spray and lysozyme, which is applied in the field of oral medicine, can solve problems such as unavailable prevention of oral diseases or daily oral cleaning, fresh breath, inconvenient driving for patients with oral diseases, and bacterial drug-resistant gastrointestinal problems, so as to achieve good prevention and Therapeutic effect, no toxic side effects, no drug dependence effect

Pending Publication Date: 2021-05-04
陕西新研药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Traditionally, antibiotics and antibacterial agents are used to kill oral pathogenic bacteria. For the convenience of use and quick effect, sprays are usually used for drug administration of oral diseases, but most of the sprays contain alcohol, which brings harm to patients with oral diseases such as driving. inconvenient
At the same time, antibiotics and bacteriostatic agents are likely to cause bacteria to develop drug resistance or side effects such as gastrointestinal discomfort, especially when oral diseases recur, the bactericidal effect of antibiotics and bacteriostatic agents will gradually decrease, affecting the therapeutic effect
Similarly, sprays containing antibiotics and antibacterial agents should not be used for a long time, and should not be used for daily health care to prevent oral diseases or for daily cleaning of the mouth and fresh breath

Method used

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  • Compound lysozyme oral spray and preparation method thereof
  • Compound lysozyme oral spray and preparation method thereof
  • Compound lysozyme oral spray and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] A kind of composite lysozyme oral spray, is made up of following raw material corresponding to weight part:

[0025] 1 part honeysuckle extract, 0.1 part astragalus extract, 0.3 part peppermint extract, 0.5 part licorice extract, 0.5 part pomegranate peel extract, 1 part xylitol, 15 parts lysozyme, 130 parts deionized water.

[0026] Honeysuckle extract, astragalus extract and peppermint extract are all made by water extraction.

[0027] The water extraction method is specifically to blend the corresponding raw materials and water according to the weight ratio of 1:10, then heat and boil for 1 hour, filter, and finally concentrate the obtained filtrate to 30% of the original volume.

[0028] Licorice extract and pomegranate peel extract are all made by alcohol extraction.

[0029] The alcohol extraction method is specifically to blend the corresponding raw materials with an ethanol solution with a volume concentration of 80% according to the weight ratio of 1:8, and th...

Embodiment 2

[0034] A kind of composite lysozyme oral spray, is made up of following raw material corresponding to weight part:

[0035] 1.5 parts honeysuckle extract, 0.2 parts astragalus extract, 0.5 parts peppermint extract, 0.8 parts licorice extract, 0.7 parts pomegranate peel extract, 2 parts xylitol, 18 parts lysozyme, 150 parts deionized water.

[0036] Honeysuckle extract, astragalus extract and peppermint extract are all made by water extraction.

[0037] The water extraction method is specifically to blend the corresponding raw materials and water according to the weight ratio of 1:10, then heat and boil for 1.3 hours, then filter, and finally concentrate the obtained filtrate to 32% of the original volume.

[0038] Licorice extract and pomegranate peel extract are all made by alcohol extraction.

[0039] The alcohol extraction method is specifically to blend the corresponding raw materials with an ethanol solution with a volume concentration of 80% according to the weight rati...

Embodiment 3

[0044] A kind of composite lysozyme oral spray, is made up of following raw material corresponding to weight part:

[0045] 2 parts honeysuckle extract, 0.3 parts astragalus extract, 0.6 parts peppermint extract, 1 part licorice extract, 1 part pomegranate peel extract, 3 parts xylitol, 20 parts lysozyme, 160 parts deionized water.

[0046] Honeysuckle extract, astragalus extract and peppermint extract are all made by water extraction.

[0047] The water extraction method is specifically to blend the corresponding raw materials and water according to the weight ratio of 1:10, then heat and boil for 1.5 hours, then filter, and finally concentrate the obtained filtrate to 35% of the original volume.

[0048] Licorice extract and pomegranate peel extract are all made by alcohol extraction.

[0049] The alcohol extraction method is specifically to blend the corresponding raw materials with an ethanol solution with a volume concentration of 80% according to the weight ratio of 1:8...

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Abstract

The invention discloses a compound lysozyme oral spray, and belongs to the technical field of oral medicines. The compound lysozyme oral spray is prepared from the following raw materials in parts by weight: 1-2 parts of a honeysuckle flower extract, 0.1-0.3 part of a radix astragali seu hedysari extract, 0.3-0.6 part of a herba menthae extract, 0.5-1 part of a liquorice root extract, 0.5-1 part of a pomegranate peel extract, 1-3 parts of xylitol, 15-20 parts of lysozyme and 130-160 parts of deionized water. The compound lysozyme oral spray does not contain alcohol, all components are extracted from natural products, and the compound lysozyme oral spray is free of toxic and side effects, free of drug dependence and good in use effect.

Description

technical field [0001] The invention belongs to the technical field of oral medicine, and in particular relates to a compound lysozyme oral spray and a preparation method thereof. Background technique [0002] The oral cavity is an important part of the digestive and respiratory systems of the human body. With the aggravation of air pollution and environmental deterioration, oral diseases are on the rise. [0003] Oral diseases are mostly caused by oral bacteria, such as oral ulcers, periodontal disease, tongue disease, dental caries, bad breath, pharyngitis, etc. Modern medicine believes that oral diseases can cause sepsis, diabetes, heart disease, etc. Therefore, killing oral pathogenic bacteria is the key to treating and preventing oral diseases. [0004] Traditionally, antibiotics and antibacterial agents are used to kill oral pathogenic bacteria. For the convenience of use and quick effect, sprays are usually used for drug administration of oral diseases, but most of t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/47A61K36/534A61K9/12A61K47/10A61P1/02A61P11/04
CPCA61K36/355A61K36/481A61K36/534A61K36/484A61K36/185A61K38/47A61K9/006A61K47/10A61P1/02A61P11/04A61K9/12A61K2236/331A61K2236/39A61K2236/333A61K2300/00
Inventor 张军文
Owner 陕西新研药业有限公司