Silver-loaded tannin polyphenol crosslinked polyvinyl alcohol antibacterial hydrogel and preparation method thereof

A technology of cross-linking polyvinyl alcohol and tannin polyphenols, which is applied in the fields of biomedical materials and polymer chemistry, can solve the problems that polyphenol-based hydrogels are rare and uncommon, and achieve short preparation time and adjustable performance Change, the effect of simple preparation method
CN112745515AActive Publication Date: 2021-05-04WUXI NO 2 PEOPLES HOSPITAL +1
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
WUXI NO 2 PEOPLES HOSPITAL
Publication Date
2021-05-04

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Abstract

The invention discloses silver-loaded tannin polyphenol cross-linked polyvinyl alcohol antibacterial hydrogel and a preparation method thereof, and belongs to the field of biomedical materials and polymer chemistry. The hydrogel is prepared from the following substances: tannin polyphenol, silver nitrate, polyvinyl alcohol and the balance of deionized water, and the antibacterial hydrogel with relatively high mechanical strength is prepared by ball milling and freezing and unfreezing methods. A characterization result shows that the hydrogel has relatively high water content, mechanical strength and high-dispersion silver nanoparticles. The preparation method has the advantages that tannin polyphenol is adopted in a hydrogel system for in-situ reduction of metal silver, introduction of other reducing agents is avoided, and in addition, a mechanical ball milling method is adopted in the preparation process, so that operation is simpler and more environmentally friendly.
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Description

technical field

[0001] The invention relates to a silver-loaded tannin polyphenol cross-linked polyvinyl alcohol antibacterial hydrogel and a preparation method thereof, belonging to the fields of biomedical materials and polymer chemistry. Background technique

[0002] Polyvinyl alcohol hydrogel is a water-soluble polymer material commonly used in medicine. It is widely used due to its low toxicity, high elastic modulus and mechanical strength, high water absorption, and good biocompatibility. In the biomedical fields such as wound dressings, artificial organ tissues, and drug sustained-release carriers. In recent years, in order to enrich the application range of polyvinyl alcohol hydrogel materials, many researchers have focused on functional modification of hydrogels. For example, the mechanical strength and water absorption properties of PVA hydrogels can be changed by introducing some natural organic macromolecules; the antifouling properties and antibacterial propert...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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