Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

A kind of nasturtium extract, antibacterial composition and application

A technology of nasturtium lotus extract and antibacterial composition, applied in the field of traditional Chinese medicine extracts, can solve the problems of enhancing curative effect, toxic and side effects, reducing drug absorption and utilization, etc.

Active Publication Date: 2021-12-31
CHENGDE TIANYUAN PHARMACEUTICAL INDUSTRY CO LTD
View PDF1 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the combination of Chinese and Western medicine has certain complexity, which may enhance the curative effect, reduce the curative effect or even produce toxic and side effects.
And for antibacterial western medicines such as azithromycin, cephalosporin antibiotics, etc., although the antibacterial effect is excellent, most of them have certain gastrointestinal reactions, and even cause gastrointestinal dysfunction and reduce the absorption and utilization of drugs.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A kind of nasturtium extract, antibacterial composition and application
  • A kind of nasturtium extract, antibacterial composition and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] The present embodiment provides a nasturtium extract, preparation method includes the following steps:

[0024] Step a, the fried carbon nasturtium, nasturtium fried carbon equivalent is placed after pH 6 to 5.5 times the weight (adjusted with citric acid pH) in water, adding the equivalent of 2.0% by weight of nasturtium cellulose fried carbon after enzyme was stirred at 40 ~ 45 ℃ hydrolysis 2.5h, then warmed to 95 ℃, 10min maintaining enzyme inactivation;

[0025] Step B, the material after the enzymatic hydrolysis speed centrifuged at 3200r / min in 7min, supernatant, ethanol was added to the ethanol concentration of 70% by volume percent, was allowed to stand for 18 h, the precipitate was removed. The feed solution at 40 ~ 50 ℃ dried in vacuo to obtain.

Embodiment 2

[0027] The present embodiment provides a nasturtium extract, preparation method includes the following steps:

[0028] Step a, the fried carbon nasturtium, nasturtium fried carbon equivalent is placed after pH 4 to 5 times the weight (adjusted with citric acid pH) in water, adding the equivalent of 1.5% by weight of the fried carbon nasturtium cellulose enzyme was stirred at 40 ~ 45 ℃ hydrolysis 3h, then warmed to 95 ℃, 15min maintaining enzyme inactivation;

[0029] Step B, the material after the enzymatic hydrolysis speed centrifugation 8min at 3000r / min, the supernatant, the concentration of ethanol was added to a volume percentage of 75% ethanol, allowed to stand for 12h, the precipitate was removed. The feed solution at 40 ~ 60 ℃ spray-dried to obtain.

Embodiment 3

[0031] The present embodiment provides a nasturtium extract, preparation method includes the following steps:

[0032] Step a, the fried carbon nasturtium, nasturtium fried carbon equivalent is placed after pH 7 times the weight of 6 (citric acid adjusted pH) in water, adding the equivalent of 2.5% by weight of the fried carbon nasturtium cellulose enzyme was stirred at 40 ~ 45 ℃ hydrolysis 2h, then warmed to 90 ℃, 15min maintaining enzyme inactivation;

[0033] Step B, the material after the enzymatic hydrolysis speed centrifuged at 3500r / min in 5min, supernatant, ethanol was added to the ethanol concentration of 75% by volume percent, was allowed to stand 24h, the precipitate was removed. The material was freeze-dried to obtain.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to the technical field of extracts of traditional Chinese medicines, in particular to an extract of nasturtium and its application, and an antibacterial composition containing the extract of nasturtium. The nasturtium extract is prepared by roasting charcoal, enzymatic hydrolysis and alcohol precipitation, and has good antibacterial effect and mild medicinal properties. When the nasturtium extract is used in combination with azithromycin, the antibacterial effect can be enhanced, the gastrointestinal reaction of azithromycin can be alleviated, and the patient's discomfort during the medication process can be reduced.

Description

Technical field [0001] Technical Field The present invention relates to herbal extracts, particularly to a nasturtium extract and its application, and nasturtium extract containing the antimicrobial composition. Background technique [0002] Ranunculaceae Trollius nasturtium plants containing Orientin, vitexin, 3,4-dimethoxy-benzamide, Li Lu amide, palmitic acid, alkaloids, coumarins, terpenoids steroids ingredients, it is possible detoxification, swelling, eyesight, having antibacterial, antioxidant, anticancer, antihypertensive, antiinflammatory and antispasmodic action, clinically useful for the treatment of acute and chronic tonsillitis, acute otitis media, acute myringitis, acute conjunctivitis Wait. [0003] Antibacterial, traditional Chinese medicinal often in combination with western medicine to improve efficacy. Golden Lotus as a clearing and detoxifying Chinese medicine, Chinese medicine was also to be combined with Western medicine. But Chinese and Western medicine com...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/71A61K33/44A61K31/7052A61K47/12A61P31/04A61K133/00
CPCA61K36/71A61K33/44A61K31/7052A61K47/12A61P31/04A61K2300/00
Inventor 周印军于海霞
Owner CHENGDE TIANYUAN PHARMACEUTICAL INDUSTRY CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com